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Biomedical subjects

T Wakao

Publications and source records attributed to T Wakao.

At least 37 records · Page 2Linked to original sources

Malignant melanoma of the spinal epidural space metastasized from the enucleated left eye after nine years without symptoms: report of a case.

A case of flaccid paraplegia due to a metastatic spinal epidural melanoma is reported. Symptoms occurred approximately 9 years after the enucleation of the left eye. A solid melanotic mass was removed almost totally. Three years after the operation, the patient had not regained the motility of the lower limbs. The need for long term follow-up and management of patients with such problems is discussed, and the pertinent literature is reviewed.

Choroid↗

[A choroid plexus papilloma of the third ventricle in the neonatal period--a case report].

The incidence of choroid plexus papilloma is about 0.5% of all intracranial tumors, but choroid plexus papilloma in the third ventricle is rare. Fortuna reported 56 cases of choroid plexus papilloma of the third ventricle in 1979. Among them, the neoplasm of the third ventricle in the neonatal period was not found. This report is a case of choroid plexus papilloma of the third ventricle in the neonatal period. A 34 day-old female was admitted to our service with complaints of head enlargement, vomiting, and convulsive seizures on January 8, 1981. Enlarged head had been noticed by her family within the first two weeks. On admission, a marked congenital hydrocephalus was diagnosed by CT scan with symmetrical dilated ventricles and no abnormal high or low density area, and V-P shunt was performed on the next day. But several days later, she suffered from progressive abdominal distension, which was disclosed due to CSF overproduction by a choroid plexus papilloma. When the tumor was recognised by enhanced CT scan, her general condition was too poor to attempt a surgical procedure, and she died on March, 19, 1981. Histologically the neoplasm was a typical choroid plexus papilloma of the third ventricle. So far as we know, this case is the first one of the choroid plexus papilloma of the third ventricle in the neonatal period.

Cerebral Ventricle Neoplasms↗

Giant serpentine aneurysm of the posterior cerebral artery.

We are reporting an unusual case of a giant serpentine aneurysm of the posterior cerebral artery (PCA). We were unable to find a report in the literature of a similar aneurysm. The microsurgical pterional approach was used for temporary clipping of the P-2 segment of the PCA, and the aneurysm was trapped successfully and excised. The discussion includes the operative approach to the giant serpentine aneurysm.

Cerebral Angiography↗

Sensitized T-lymphocytes against paternal histocompatibility antigens cause intrauterine fetal death and growth retardation.

The influence on pregnancy of sensitized T lymphocytes against male histocompatibility antigens was investigated using inbred strain mice. Number of abortion, litter size, fetal weight and placental weight were studied on 18th day of pregnancy in the mice which were administered intravenously with T lymphocyte enriched fraction of sensitized spleen cells against allogeneic male histocompatibility antigens. The incidence of abortion in the experimental mice was higher than that in control mice. Mean fetal weight in the experimental mice was less than that in the control mice although mean placental weight in the experimental mice was unaffected. Those results show that immunologic interruption of pregnancy due to histoincompatibility between mother and fetus can occur and that the immunologic interruption of pregnancy is caused by sensitized T lymphocytes against paternal inherited histocompatibility antigens. Possible process of the immunologic interruption of pregnancy is discussed.

Animals↗