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T Wada

Publications and source records attributed to T Wada.

At least 793 records · Page 44Linked to original sources
PubMed1988

[A case of anaplastic astrocytoma associated with pituitary adenoma].

A case of anaplastic astrocytoma associated with pituitary adenoma is reported. The patient was a 33-year-old male, who was admitted with complaints of sensory aphasia, slight left motor paresis, and visual field defects. Neurological examination disclosed sensory and motor aphasia, Gerstmann's syndrome, slight left motor paresis, right homonymous hemianopsia, and bilateral choked discs. Computed tomography revealed a low density mass lesion with slight enhancement in the left temporal region and a ring-like enhanced mass lesion in the suprasellar region. In MRI, both the left temporal and the suprasellar lesions are depicted as low signal intensity areas in T1 weighted imaging, but as high signal intensity areas in T2 weighted imaging. Craniotomy was performed and both tumors were almost totally removed. The tumor in the left temporal region was diagnosed as anaplastic astrocytoma and the other in the suprasellar region was diagnosed as chromophobe adenoma. Multiple primary intracranial tumors of different cell types are rare. About a hundred cases can be found in medical literature. More than two thirds of them are cases of glioma associated with meningioma, but other combinations of tumors are extremely rare. We now report this case of astrocytoma associated with pituitary adenoma. In the literature, there are only 5 cases of similar combination. It is believed that astrocytoma and pituitary adenoma are histologically different. In three of five reported cases, the tumors were in close proximity to each other, but it is doubtful that their close proximity was related to the fact that they developed concurrently.

Adenoma↗
PubMed1988

Tris(2,4,6-tribromophenoxy)dichlorophosphorane as a condensing agent: a new type of activation of phosphodiester components in the phosphotriester method.

The title compound (BDCP) was found to be effective for the rapid internucleotidic bond formation in the presence of 3-nitro-1,2,4-triazole (NT). Mechanism of the condensation reaction was elucidated by means of 31P-NMR. It was proved that there was no active species but the desired nucleotide derivatives, phosphorochloridate and phosphorylnitrotriazole, in the reaction mixture. Thus, the side-reaction of excess condensing agent in the conventional phosphotriester method was overcome.

Indicators and Reagents↗
PubMed1988

[Effect of hypertension on asymmetrical septal hypertrophy: an echocardiographic study].

The effect of hypertension on asymmetrical septal hypertrophy was studied by echocardiography to differentiate idiopathic asymmetrical septal hypertrophy (ASH) from ASH with hypertension. One hundred eight patients with ASH proven by echocardiography were categorized in two groups; 53 patients with hypertension (greater than 160 systolic, greater than 95 diastolic) (hypertensive group: HT) and 55 patients with normal blood pressure (normotensive group: NT). Septal hypertrophy was classified as mid-portion (M-type), diffuse (D-type), and basal (B-type) hypertrophy by the long-axis view, and also diffuse (I-type), anterolateral (II-type), anteroseptal (III-type), and anterior septal (IV-type) by the short-axis view, respectively. Endomyocardial biopsy and left ventriculography were performed in 50 patients (18 hypertensives and 32 normotensives). In the hypertensive group, 45%, 30%, and 25% of cases had diffuse, basal and mid-portion hypertrophy, respectively. There was no case in the basal hypertrophy whose biopsy findings were compatible with hypertrophic cardiomyopathy. In the normotensive group, 78% and 22% of patients had midportion and diffuse hypertrophy, respectively, but none of them had the basal hypertrophy. Type IV was seen in only six patients in the normotensive group.

Adult↗
PubMed1988

Evaluation of media, protein supplements and potassium concentration for human in vitro fertilization and embryo transfer by preimplanted mouse embryo development.

A two-cell mouse embryo was used to investigate the effect of three different media and protein supplements together with different potassium (K+) concentrations on embryo development. The embryos of the ICR mouse showed higher expanded blastocyst rates in Biggers-Whitten- Whittingham (BWW) than in Ham's F10 (F10) and Whittingham's T6 (T6). The embryos of the C57BL X CBA strain showed the highest hatching rate in BWW but the expanded blastocyst rate was highest in F10. Embryos from both strains developed more rapidly with BSA supplement with no difference between human serum (HS) and fetal cord serum (FCS). Relatively higher K+ concentrations (7.7 mM and 17.8 mM) suppressed 2-cell mouse embryo development. F10 and BWW were used for human in vitro fertilization and embryo transfer (IVF-ET). The fertilization rate was significantly higher in BWW than in F10. Two viable pregnancies were obtained in BWW cycles. This study supports the use of BWW over other standard media for human IVF-ET.

Animals↗
PubMed1987

Phase-dependent shift of free-running human circadian rhythms in response to a single bright light pulse.

Responsiveness of free-running human circadian rhythms to a single pulse of bright light was examined in a temporal isolation unit. Bright light (5000 lx) of either 3 or 6 h duration, applied during the early subjective day, produced phase-advance shifts in both the sleep-wake cycle and the rhythm of rectal temperature; the light pulse had essentially no effect on the phase of the circadian rhythms, when it was introduced during the late subjective day or the early subjective night. The results indicate that bright light can reset the human circadian pacemaker.

Body Temperature↗