Search PubMed⌕ Search

Biomedical subjects

T W Tao

Publications and source records attributed to T W Tao.

29 records · Page 2Linked to original sources
PubMed1976

[Human non-epithelial tumors in "nude" mice: morphology and growth characteristics].

Morphology and growth characteristics of an osteosarcoma and a glioblastoma are described after direct transplantation in nude (thymusless) mice. In osteosarcoma neither characteristic had changed after 14 months' observation. In contrast, some of the glioblastoma transplants (22 months' observation) showed dedifferentiation of morphology and grew faster than others derived from the same biopsy. The possible reasons for the different growth pattern of the two tumors are discussed.

Animals↗
PubMed1976

Reconstitution capacity of bone marrow cells from nude mice in radiation chimeras.

Lethally irradiated mice were reconstituted with bone marrow cells from 'nude' or normal mice. It was found that the radioprotective capacity of bone marrow cells from normal and thymusless 'nude' mice is similar and that the immune responses to sheep red cells in radiation chimeras reconstituted with normal and nude bone marrow cells are also similar. Bone marrow cells from nude mice, in spite of the lack of the thymus, develop into hematopoietic cells and contain also T-precursor cells.

Animals↗
PubMed1975

The immune response of mice to phiX174. The potentiation of B-cell immunity and the suppression of T-cell help by pertussis vaccine.

The primary and secondary responses to phiX174 have been studied in T cell-deprived (T- minus) and control CBA mice including sham-operated (T+) and normal mice. The effect of pertussis on the immune response of these mice has been measured. It is concluded that: (1) the gammaG and memory responses to phiX are produced in T- minus mice even though greatly reduced in comparison with T+ and normal mice; (2) pertussis appears to enhance the gammaG response in T- minus mice while suppressing it in T+ and normal mice.

Adjuvants, Immunologic↗
PubMed1966

Primary-type antibody response in vitro.

Organ cultures of lymph nodes obtained from nonimmunized rabbits were incubated with bacteriophage d, X174; as a result, 19S antibody was produced first, and then 7S antibody. Differences between this response and the secondary response to d? X174 induced in vitro suggest that the foriiier is a primary response.

Animals↗