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Biomedical subjects

T W Miller

Publications and source records attributed to T W Miller.

At least 55 records · Page 3Linked to original sources
PubMed1987

Disputed child custody: strategies and issues in mediation.

Disputed child custody is a significant life stressor for both adults and children. Recent efforts have been made to develop a model for family mediation and subsequent clinical strategies that can attempt to address the stressors involved in divorce and perhaps resolve, through mediation, the posttrauma stress experienced by both spouses and children. Reviewed is the literature on the impact of separation and divorce on families and the use of family mediation to resolve disputes. It further addresses psychologic factors involved in the mediation process and the possible effects of mediation on divorce. An established family mediation model for treatment is presented in detail, as are clinical issues often addressed in the family mediation process. Issues and import for clinical application and research are offered.

Child↗
PubMed1986

Effects of short-term denervation on avian muscle spindle structure.

The role of the nerve in maintaining the ultrastructural integrity of avian muscle spindles was investigated by denervating the pigeon's extensor digitorum communis for periods of 10, 19, and 28 days. The equatorial region of control intrafusal fibers had a reduced density of myofilaments. Sensory endings contained mitochondria and structures resembling synaptic vesicles, and were associated with satellite cells. In the polar region, fibers had a high concentration of myofilaments; small motor endings, unlike sensory endings, lay outside of the fiber's basal lamina. The outer capsule consisted of thin, tightly layered cells which gradually became reduced in number distal to the equatorial region. In both equatorial and polar regions the capsule became more disrupted with longer denervation periods, and lysosomes and phagocytes became more abundant. The equatorial region of denervated fibers contained many myofibrils and some had peripherally-located nuclei, unlike the controls; sensory terminals were absent. The polar region of some fibers had disorganized myofilaments and others had a reduced myofilament density. Fiber diameters increased significantly in both regions. Thus, denervated intrafusal fibers lost some characteristics which distinguish them from extrafusal fibers.

Animals↗
PubMed1985

The lack of antifungal activity by avermectin B1a.

Streptomyces avermitilis produces avermectin, oligomycin and a polyene antifungal. The latter two compounds account for the antifungal activity in the methanol extracts of the fermentation broth. Pure avermectin does not inhibit fungi or affect fungal chitin metabolism.

Antifungal Agents↗
PubMed1984

Ischemic degeneration of the avian muscle spindle.

The neurovascular supply to the pigeon's extensor digitorum communis muscle was disrupted. The muscle spindles were studied by light and electron microscopy to determine whether their degeneration was compatible with regeneration by activation of satellite cells within an intact spindle capsule. The denervation and ischemia induced intrafusal muscle fiber necrosis and degeneration of the sarcolemma and basal lamina. The muscle fibers in the equatorial region were often absent and their sites were indicated by collagenous caps which usually covered the sensory nerve terminal regions. These collagenous caps enclosed amorphous material derived from the intrafusal fibers and degenerating mitochondria from the sensory terminals. In this equatorial region, the basal lamina was present only under the collagenous cap and was disrupted elsewere . The cells of the muscle spindle capsule were more sparse or absent, but the collagen content had increased. The sheath lacked continuity, containing numerous gaps. These observations indicate that the basal lamina does not remain intact, and regeneration may not occur by activation of satellite cells within the former basal lamina, as reported for regenerating rat muscle spindles. This suggests that the mechanisms of regeneration of muscle spindles in rat and pigeon muscle may not be similar.

Animals↗