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Biomedical subjects

T V Savchenko

Publications and source records attributed to T V Savchenko.

At least 55 records · Page 3Linked to original sources
PubMed1979

[Effect of thyroxine on the duration of the phases of the hepatocyte mitotic cycle at different times of day].

The lengths of the synthetic phase (S) and postsynthetic gap plus a half of the mitotic time (G2+1/2 M) has been investigated in hepatocytes of control and thyroxine-treated male white rats using percent labeled mitosis curves after injection of isotope at 10, 16, 22 and 4 o'clock. In the control, the minimum lengths of G2 lasted 3.0 hours without being changed during 24 hours. On the contrary, G2+1/2 M and S varied from 3.2 to 4.4 and from 8.0 to 9.5 hours, accordingly. A prolonged administration or hormone induced changes in duration of all the above phases whose alterations in thyroxine-treated group of animals showed 2.0--3.0, 2.9--3.4 and 6.4--11.3 hours, respectively. During 24 hours, there was observed a characteristic pattern of changes in the labeling index (LI) of both groups of animals. It has been established for both the groups that the increased in LI coincides with the shortening of S-phase. The data allow to conclude that some intracycle mechanisms may exist controlling the cell division and exerting their effects on the cells at the end of G1-phase and during G2-phase. Thyroxine is a regulator of cell proliferation, and its effect was found to occur due to the intracycle mechanisms of cell cycle kinetics.

Animals↗
PubMed1979

[Correction of the lymph outflow using a lymphovenous anastomosis].

The authors report that the operation of end-to-side lympho-venous anastomosis was developed in experiment by submersion. In clinical conditions the operation was performed on 22 patients with chronic postthrombic venous insufficiency of lower extremities. The best results were obtained in patients with secondary lymphostasis and in edematic form of postthrombic venous insufficiency. In diseases of the veins operations were performed as a preliminary step of the surgical correction of the venous outflow. Remote results were observed during one year.

Adult↗
PubMed1976

[Diagnosis and treatment of post-traumatic chronic venous insufficiency of the lower limbs].

The authors report 87 observations on posttraumatic chronic lymphovenous insufficiency of the lower extremities. Basic methods of examination of such patients; rheovasography, polarography, thermography, veno- and lymphography are described. Grounds are given for the complex treatment of chronic lymphovenous insufficiency after A.V. Vishnevsky and A.A. Vishnevsky technic and the procedure of fibrolysis with supra- and subfascial ligation of communicating veins.

Adult↗