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T V DiSilvio

Publications and source records attributed to T V DiSilvio.

4 recordsLinked to original sources

Computer-assisted quality control: considerations for program design.

A well-designed laboratory computer system has the potential of enhancing all phases of quality control. Of most importance is the choice of an underlying approach that is statistically valid and robust. Specification of quality goals, participation in regional programs, and use of a flexible multi-rule approach are recommended. Careful attention to general and specific design is necessary to achieve full system potential. The design process must include detailed consideration of file and record structure, data integrity, flexibility of input and output, and display and report formats. For statistical run evaluation, theoretic validity, operational process, and ease of understanding by the user must be considered.

Computers

Additional day-to-day precision estimates based on regional chemistry quality control data.

State-of-the-art precision values are presented for the following serum constituents: aldolase (EC 4.1.2.13), alpha-hydroxybutyrate dehydrogenase (EC 1.1.1.30), cholinesterase (EC 3.1.1.8), cortisol, gamma glutamyl transferase (EC 2.3.2.2), haptoglobin, immunoglobulins, lactic acid, leucine aminopeptidase (EC 3.4.1.1), total lipids, osmolality, protein fractions, T3 uptake, thyroxine and vitamin B12. Precision estimates are based on values reported for four lyophilized serum pools analyzed by participants in the Pennsylvania Association of Clinical Pathologists regional quality control program for clinical chemistry, during 1976, 1977 and 1978. Use of the upper limit of the "most common range" of precision (that range including the 75 percent most precise laboratories) as a warning level for trouble-shooting is advocated.

Blood Chemical Analysis