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Biomedical subjects

T V Baĭdina

Publications and source records attributed to T V Baĭdina.

8 recordsLinked to original sources
PubMed2006

[Method for determining leukocytic lipid-releasing capacity in the diagnosis of mechanisms responsible for atherogenesis in patients with coronary heart disease and ischemic stroke].

The authors have studied the mechanism responsible for neutrophilic accumulation and release of protein-lipid complexes in patients with atherosclerosis and the clinical value of this reaction. They present the results of experimental studies and clinical observations in the groups of patients with ischemic stroke, coronary heart disease, bronchial asthma, chronic obstructive pulmonary disease, and rheumatoid arthritis. Whether the process of neutrophilic and release of protein-lipid can be in vitro modulated in a 3-day culture has been demonstrated. The high diagnostic value of the method for determining the lipid-releasing capacity of leukocytes is shown. Some proteins involving in the formation of pathogenic protein-lipid complexes are identified. There is evidence for the use of new differential criteria for visceral diseases originating from atherosclerosis.

Adolescent↗
PubMed2006

[Leucocytes' ability to accumulate and secrete cholesterol is a nonspecific factor of immune inflammation in patients with atherothrombotic stroke].

The aim of the study was investigation of nonspecific inflammation markers in atherosclerotic injury of major arteries of the head (MAH). A complex study, including duplex ultrasonography, CT, measurement of cholesterol and its fractions, has been conducted in 85 patients with atherothrombotic (72 patients) and lacunar (23 patients) stroke. The ability of leucocytes' culture to accumulate and secrete cholesterol in vitro was studied as a nonspecific inflammatory marker of lesion of atherosclerotic MAH. A high level of this index was characteristic of atherothrombotic type of stroke comparing to lacunar stroke and the control group. Furthermore, high levels of this index correlated with severity of atherosclerotic injury of MAH, in particular with plaques. The dynamics of the index after 24-day therapy by statins (vasilip) is presented. We suppose that the protective influence of statins in patients after ischemic stroke may be caused by the effects on the level of immune competent cells including reducing leucocytes ability to accumulate and secrete protein-lipid complexes.

Adult↗
PubMed2005

[Endothelium dysfunction in patients with ischemic stroke].

A vasomotor endothelial function has been studied in 57 patients with ischemic stroke using ultrasound by the reaction of the brachial artery to reactive hyperemia. The duplex scanning of brachyocephalic arteries was conducted. Twenty-four patients had impaired endothelial-dependent vasodilatation. Endothelial dysfunction was associated with cholesterol blood level and smoking. Aging, positive family history and arterial hypertension did not affect this parameter. A level of vasomotor dysfunction correlated with intima-media correlation, the presence of plaques in the carotid arteries and internal carotid artery occlusion. Impaired endothelial-dependent vascular relaxation occurred more frequently in atherothrombotic than in lacunar stroke and in patients with a severe brain damage.

Adult↗
PubMed1993

[Multiple sclerosis: acute state or malignant course?].

Multiple sclerosis (MS) which had developed in a 19-year-old female patient took a malignant course and terminated fatally three years after first symptoms. The case was characterized by an acute onset, seven severe exacerbations against combined pyramidal, cerebellar, visual, psychopathological and hyperkinetic disorders. The authors believe improper application of the term "acute" to rapid lethal outcome cases. In their opinion, they should be called cases of MS malignant course, the latter implying an unfavourable outcome of MS due to primarily truncal location of the demyelination process.

Acute Disease↗
PubMed1990

[Multiple sclerosis in childhood].

The authors discuss the problems of the age-associated range of multiple sclerosis, characteristics of its clinical manifestations and course in childhood. Provide two cases of multiple sclerosis that had set in 11-year- and 14-year-old children. The first case was marked by a polysymptomatic debut with retrobulbar neuritis of the optical nerves, astereognosis and atetoid hyperkinesis in the hand. The second case was characterized by remitting oculomotor, vestibular, pyramidal disorders associated with facial neuropathy.

Athetosis↗
PubMed1988

[Suprasegmental autonomic regulation in syringomyelia patients and its alteration during radionuclide therapy].

Limbic-reticular dysfunction due to pathologic rearrangement in functional intracentral relations was evidenced in 85 syringomyelic patients. The dysfunction was initiated by the syringomyelic inflicted focus within the brainstem (syringobulbia) or spinal cord. Displayed were the psychoemotional, unspecific activational and hemodynamic correlates of this pathophysiological phenomenon. This is the first description of the radioactive iodine positive effect on limbic-reticular dysfunction in syringomyelia.

Adult↗
PubMedDate not supplied

[Changes in poststroke asthenia in the course of rehabilitation].

Questionnaire (asthenia MFI) survey of 2043 patients early in rehabilitation after ischemic stroke in the territory of the carotid arteries was made. Asthenia was detected in 81% patients with elevated total score, physical, psychic asthenia, hypoactivity and low motivation. Asthenia was secondary and correlated with social maladaptation. Rehabilitation in a specialized neurological department of health resort Ust-Kachka leads to positive changes in the above indices.

Adult↗