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Biomedical subjects

T Ueo

Publications and source records attributed to T Ueo.

At least 37 records · Page 2Linked to original sources

Arthroscopic resection of the shelf (mediopatellar plica) in the knee under local anesthesia in outpatient clinic.

Forty-two knees with symptomatic mediopatellar plicae (shelves) were managed using the operative method under local anesthesia. Of these, thirty-one knees had isolated mediopatellar plicae, and eleven had other associated intra-articular pathologic condition, such as meniscal tear, lateral patellar tracking, osteochondritis dissecans, and minor osteoarthritic changes. The clinical results were excellent or good in thirty-seven (88%) patients, fair in five patients after an average follow-up of twenty-five months. No case showed deterioration after surgery. Because there are no definitive criteria for the indication of shelf resection, arthroscopic resection of the shelf under local anesthesia is recommended if there is any possibility of it being the cause of knee pain.

Adolescent↗

Ultrasound diagnosis of pathology of the anterior and posterior cruciate ligaments of the knee joint.

We established a method of diagnosing pathologic conditions of both the anterior cruciate ligament (ACL) and the posterior cruciate ligament (PCL) by using ultrasound. Normal ACL and PCL were delineated as hyperechoic images on the screen in sagittal and transverse sections. On the other hand, no image of the ligament could be seen when the ligament was ruptured. We examined nine ACL and five PCL injuries by our method. This is a safe and an effective method of determining the rupture of ACL and PCL.

Anterior Cruciate Ligament↗

Rupture of the labra acetabularis as a cause of hip pain detected arthroscopically, and partial limbectomy for successful pain relief.

We describe two patients who had pain of unknown cause in the right hip for many years. Plain roentgenograms results were normal, and arthrography did not reveal any abnormal findings. Because clinical examinations strongly suggested internal derangement of the hip, arthroscopies of the hips were performed. The labra acetabularis were observed to be ruptured at the posterior margin of the acetabulum. Partial limbectomies were performed by the posterior approach, and the patients showed marked decrease in hip pain postoperatively. This report shows that a solitary lesion of fibrocartilaginous tissue of the hip can cause hip pain. These conditions can be easily misdiagnosed as sciatica.

Acetabulum↗

Effectiveness of lymphocytapheresis in a patient with ankylosing spondylitis.

Immunomodulation by lymphocytapheresis (LCA) was carried out in a patient with ankylosing spondylitis (AS) who suffered severe pain in joints and back. LCA was performed once a week and 3 x 10 9 lymphocytes were extracted each time. Fifteen courses of LCA were completed. The joint score was gradually decreased and the improvement was maintained 11 months after treatment. The population of NK cells detected by Leu-7 and Leu-11 monoclonal antibodies decreased and HLA-DR positive CD3 cells increased during and after the treatment. The effectiveness of LCA in AS may confirm the participation of immunological mechanisms in the pathogenesis of AS.

Adult↗

Five-year results of bipolar arthroplasty with bone grafts and reamed acetabula for osteoarthritis in young adults.

Bateman universal proximal femoral arthroplasty combined with acetabular reaming was performed in 35 cases of osteoarthritis of the hip joint. The patients were from 21 to 59 years of age (average, 41 years of age) at the time of operation. The postoperative outcome for a middle term ranging from two to eight years, with an average of five years and nine months, was studied along with postoperative migration of the outer head. The clinical outcome, assessed by the evaluation criteria for hip function proposed by the Japanese Orthopaedic Association, was favorable. A stable average score of greater than 80 occurred for eight years postoperatively; the average preoperative score was 45. Of the 35 cases, seven cases (20%) had an upward migration of the outer head, and one case (2.9%) had an inward migration of 5 mm or more, but the migration did not affect the clinical outcome in any case. There was no certain relationship between the degree of rotation of the outer head and the extent of its migration. Migration of the outer head was prevented by postoperative exercise, in which total loading was initiated after the completion of the radiolucent zone around the outer head and its circumferential zone of osteosclerosis.

Acetabulum↗

Biomechanical analysis of Perthes' disease using the finite element method: the role of swelling of articular cartilage.

Radiologically, widening of the joint space in the hip affected with Perthes' disease is encountered in the very early stage of the disease when no changes are yet noted in the bone. This suggests that swelling of the articular cartilage may be taking place in the affected joint. Since the intra-articular volume of a ball-and-socket joint with a deep fossa, such as the hip joint, cannot be readily altered, this swelling is expected to exert a marked imbibitional pressure within the bone of the femoral head. We speculated that this biomechanical factor might play an important role in the development of Perthes' disease. A two-dimensional finite-element model with 853 elements was constructed to simulate the hip joint of a child. Stress distribution in epiphyseal bone of the femoral head was computed under the condition of swelling of articular cartilage, and biomechanical effects of the imbibitional pressure on the epiphysis were investigated. On the assumption that high stress concentrated in the bone caused collapse and necrosis, the process of development of Perthes' disease was simulated. The results of simulation using theoretical values were in close agreement with such clinical findings as destruction of the lateral portion of the epiphysis in the early stage, final fragmentation of the epiphyseal bone, and metaphyseal bone destruction.

Biomechanical Phenomena↗

Scintigraphy in nontraumatic femoral head necrosis.

We performed serial 99mTc-MDP bone scintigraphy of nontraumatic femoral head necrosis in 14 hips of 10 patients. The uptake of isotope was decreased in the very early stage, and either variable or increased at the stage when symptoms appeared. A variable uptake changed to increased uptake in 3 of 10 patients, but there was no hip in which an increased uptake changed to a variable uptake. No relationship was demonstrated between the scintigraphic appearance of the femoral head and the pain and function of the hip.

Adult↗

Biomechanical aspects of the development of aseptic necrosis of the femoral head.

With the advancement of computer technology it has been possible to determine stress distribution in bone by the finite-element method (FEM), for a pathomechanical analysis of aseptic necrosis of the femoral head. Development of aseptic necrosis of the femoral head has been considered to be coincident with ischemic changes in the bone. However, the area of necrosis in the femoral head does not correspond to vascular distribution. We speculated that not only biological, but also biomechanical factors might play an important role in the development of femoral head necrosis. A two-dimensional finite-element model, with 801 elements and 454 nodes, was constructed to mimic the hip joint. Conditions for the disease were simulated on the assumption that concentrated areas of high stress cause changes in the biomechanical properties of bone, according to Wolff's law, such as necrosis or sclerosis. Results of the simulation correlated well with clinical findings. Biomechanical factors should be considered, not only to prevent the collapse of bone structure but also to limit the spread of bone necrosis in the early phase of the disease.

Biomechanical Phenomena↗

The effect of thoracic duct drainage on lymphocyte dynamics and clinical symptoms in patients with rheumatoid arthritis.

Thoracic duct drainage (TDD) was performed in 4 patients with severe rheumatoid arthritis. Clinical effects were apparent in all during drainage, but the term of TDD and the cumulative number of lymphocytes drained had no direct relation to the improvement of clinical symptoms. The number of lymphocytes in the peripheral blood increased despite discharge of lymphocytes from the thoracic duct in the very early stage of drainage, suggesting that lymph drainage from thoracic duct accelerates migration of lymphocytes from lymphocyte pools to the blood stream. Biopsy specimens of synovial membranes obtained post-TDD showed marked decrease of mononuclear cell infiltration as compared to the specimens obtained preoperatively. These findings suggest that clinical effectiveness may be due not only to systemic immunosuppression induced by lymphocyte depletion but also to accelerated migration of inflammatory cells from the synovial tissues to the blood stream occurring with dynamic change of lymph flow during TDD.

Adult↗

Linear melorheostotic scleroderma with hypertrichosis.

On the basis of clinical features and histological findings, cutaneous manifestations of linear melorheostotic scleroderma are apparently derived from a localized proliferative disorder and are not secondary to bone changes. If the hypertrichosis has the same origin as the osteocutaneous changes, melorheostosis may represent a congenital disorder with both ectodermic and mesodermic components.

Adult↗