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Biomedical subjects

T Tulandi

Publications and source records attributed to T Tulandi.

At least 109 records · Page 6Linked to original sources
PubMed1988

Closure of laparotomy incisions with or without peritoneal suturing and second-look laparoscopy.

The effect of peritoneal closure after reproductive surgery by Pfannenstiel incisions was studied clinically and by second-look laparoscopy. No difference was found in the length of hospital stay, the incidence of wound complications, and other postoperative complications after abdominal closure with (group peritoneal closure, n = 168) or without peritoneal suturing (group no peritoneal closure, n = 165). The laparoscopic findings of 63 patients in the group with peritoneal closure and 57 patients in the group without closure were compared with those in 150 infertile women with no history of abdominal surgery (control group). No adhesions to the anterior abdominal wall were found in the control group. The incidence of these adhesions was not statistically different between the group with peritoneal closure (22.2%) and the group without peritoneal closure (15.8%). This study suggests that there is no difference in postoperative complications, wound healing, and adhesions to previous laparotomy incisions after laparotomy closure with or without peritoneal suturing.

Adult↗
PubMed1988

Tubal occlusion as a result of retained ectopic pregnancy: a case report.

During a laparoscopic examination for infertility, a retained ectopic pregnancy was unexpectedly found occluding the fallopian tube. This case report raises concerns that observant management and medical treatment of ectopic pregnancy may lead to intratubal retention of and occlusion by chorionic tissue.

Adult↗
PubMed1988

Histopathologic study of ampullary and isthmic tubal ectopic pregnancy.

A histopathologic study of 84 ampullary and seven isthmic tubal ectopic pregnancies was conducted. In 52.2% of ampullary pregnancies, the gestations were found intraluminally, and in most of these cases (85.1%), the muscularis was preserved. In isthmic pregnancies, the gestations were usually found extraluminally or both intraluminally and extraluminally. The disruption of the tubal wall was more extensive in isthmic pregnancy. This study suggests that in isthmic pregnancy, the trophoblast penetrates the tubal wall relatively early. It appears that linear salpingostomy could be done for ampullary pregnancy without jeopardizing luminal integrity. Its use for isthmic pregnancy is still unclear.

Fallopian Tubes↗
PubMed1988

Reproductive performance of women after two tubal ectopic pregnancies.

Twenty-four women who had undergone total salpingectomy due to ectopic pregnancy and who subsequently underwent a laparotomy for a second ectopic pregnancy in their opposite tube were treated by the author. Treatment consisted of linear salpingostomy (n = 20) and partial salpingectomy (n = 4). The intrauterine pregnancy rate after linear salpingostomy in women who attempted to conceive was 50%, and the incidence of a third ectopic pregnancy was 27.8%. These findings suggest that linear salpingostomy should be considered in the management of a second tubal pregnancy in women with a single tube. The high incidence of a third ectopic pregnancy, however, is concerning.

Adult↗
PubMed1987

Effect of estrogen on the growth hormone response to the alpha-adrenergic agonist clonidine in women with menopausal flushing.

The serum GH response to the alpha 2-adrenergic receptor agonist clonidine (0.15 mg, iv) was measured in 8 postmenopausal women with hot flushes before and during treatment with the conjugated estrogen premarin (1.25 mg, orally daily for 4 weeks), 9 normal premenopausal women, and 12 normal men. The men had a significantly greater GH response than did the age-matched premenopausal women (P less than 0.05). The mean individual peak GH response was significantly higher in the premenopausal compared with the postmenopausal women (P less than 0.05). Premarin decreased the number of hot flushes (P less than 0.01), but had no effect on the GH response to clonidine. These results suggest that estrogens do not enhance alpha 2-adrenergic mechanisms that regulate GH secretion and that improvement in menopausal flushing after estrogen therapy is not mediated by an effect on central alpha 2-adrenergic function.

Adrenergic alpha-Agonists↗
PubMed1987

Diabetes insipidus: a postpartum complication.

Sheehan's syndrome and diabetes insipidus were diagnosed in a 31-year-old woman seven months after postpartum bleeding with a short duration of hypotension. The diagnosis of diabetes insipidus was established by the inability to concentrate urine during water deprivation and the marked increase in urinary osmolality after administration of 1-Desamino-8-D-arginine-vasopressin (DDAVP). Obstetricians should be aware of diabetes insipidus as a postpartum complication.

Adult↗
PubMed1986

Effect of guanfacine, an alpha-adrenergic agonist, on menopausal flushing.

The effect of guanfacine (0.5 mg/day), an alpha-adrenergic agonist, on menopausal flushing, was studied in a double-blind, placebo-controlled crossover study in 11 patients. Both guanfacine and placebo significantly decreased the total number of flushes from baseline values. There was, however, no significant difference between placebo and guanfacine. Larger doses of guanfacine may be required to exert a therapeutic effect similar to that reported in the literature with the alpha-adrenergic agents, clonidine and alpha-methyldopa.

Climacteric↗
PubMed1986

Salpingo-ovariolysis: a comparison between laser surgery and electrosurgery.

A prospective, randomized study comparing the result of salpingo-ovariolysis using the carbon dioxide (CO2) laser and the microdiathermy needle was conducted. The pregnancy rate after laser surgery was 53.3% (n = 30) and after electrosurgery was 51.5% (n = 33) at 2-year follow-up. Although the surgery-conception interval after laser surgery (9.9 +/- 2.0 months) tended to be shorter than after electrosurgery (13.1 +/- 2.0 months), no statistical difference was reached. This report suggests that there is no difference between the pregnancy rate after salpingo-ovariolysis with the use of the CO2 laser or with the use of the microdiathermy needle. The surgery-conception interval, however, tends to be shorter after laser surgery. A larger series of patients is required to clarify the latter.

Adult↗
PubMed1986

Induction of fertility in a man with hypogonadotropic hypogonadism with very low seminal volume.

Pituitary function studies were performed on a 31-year-old man who had oligospermia and a very low seminal volume (0.1 ml). The low testosterone and gonadotropin levels, the remarkable testosterone response to human chorionic gonadotropin (hCG) stimulation, and the sluggish luteinizing hormone (LH) response to luteinizing hormone stimulating hormone (LH-RH) stimulation suggested the presence of hypogonadotropic hypogonadism. Treatment with a combination of human menopausal gonadotropin (hMG)-hCG resulted in the increase in the volume of seminal fluid and the sperm density. His wife achieved two pregnancies during the treatment. This report indicates that the findings of oligospermia and very low seminal volume should be followed by an investigation of the hypothalamo-pituitary testicular axis. Fertility in men with hypogonadotropic hypogonadism can be effectively induced with a combination of hMG-hCG treatment.

Adult↗
PubMed1985

Effect of naloxone on menopausal flushes, skin temperature, and luteinizing hormone secretion.

The effect of naloxone (1.4 mg/hr for 3 hours) on subjectively experienced menopausal flushes, skin temperature, and luteinizing hormone secretion was investigated in seven women in a double-blind, saline-controlled, crossover study. Naloxone had no effect on the number of subjective flushes, episodic skin temperature elevation, luteinizing hormone pulses, variability of luteinizing hormone secretion, or total luteinizing hormone secretion. This study suggests that a naloxone-sensitive opioid mechanism is not active in modulating luteinizing hormone secretion in the postmenopausal woman and that opioid receptor blockade is not effective in altering the frequency of menopausal flushes.

Climacteric↗
PubMed1985

Plasma cortisol concentrations in women with menopausal flushes.

A wide variety of stressful stimuli has been shown to increase cortisol secretion. Women with post-menopausal flushes report that their flushes cause acute physical discomfort. We studied the effect of hot flushes on plasma cortisol concentrations in 7 women with frequent post-menopausal flushes. Subjects were monitored subjectively and objectively with a skin temperature recorder over a 3-h period (8:00-11:00 a.m.). The 8:00 a.m. cortisol levels were the highest. These were followed by a decline in plasma levels, suggesting the normal circadian variation in cortisol concentrations. No increase in plasma cortisol levels was found during or after the flush episodes. These results suggest that, in our experimental setting, post-menopausal flushes do not increase cortisol secretion.

Circadian Rhythm↗
PubMed1985

A comparison between laser surgery and electrosurgery for bilateral hydrosalpinx: a 2-year follow-up.

The overall pregnancy rate after salpingostomy in women with complete bilateral terminal tubal occlusions was 26.9%. No difference was found in the intrauterine pregnancy rate and the surgery-conception interval between salpingostomy with the CO2 laser or the microdiathermy needle at a 2-year follow-up. The advantage of the CO2 laser in other reproductive surgery remains to be seen.

Adult↗