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Biomedical subjects

T Tsuzuki

Publications and source records attributed to T Tsuzuki.

At least 199 records · Page 11Linked to original sources
PubMed1981

Hepatic resection upon patients with jaundice.

Fourteen jaundiced patients with carcinoma at the bifurcation of the hepatic ducts, primary carcinoma of the liver and congenital cystic dilation of the intrahepatic bile ducts underwent hepatic resection without an operative mortality after the jaundice was relieved preoperatively. All patients did well, with jaundice and fever being absent postoperatively, although nine patients died of a recurrence of carcinoma in the follow-up period. It is now clear that the jaundiced patient become candidates for hepatic resection.

Adult↗
PubMed1981

Surgical anatomy of the hepatic veins and the inferior vena cava.

Accurate knowledge of the surgical anatomy of the hepatic veins and inferior vena cava is indispensable for surgeons, since catastrophes usually occur in this area. Material from 83 autopsies was examined concerning the patterns of ramifications of the hepatic veins along with right suprarenal and inferior phrenic veins as well as the length of the various segments of the inferior vena cava. Various maneuvers performed during operations on the liver are dependent upon the surgical anatomy of the hepatic veins and the inferior vena cava.

Adolescent↗
PubMed1979

Lambda bacteriophage-mediated transduction of ColE1 deoxyribonucleic acid having a lambda bacteriophage-cohesive end site: selection of packageable-length deoxyribonucleic acid.

An in vitro recombinant ColE1-cos lambda deoxyribonucleic acid (DNA) molecule, pKY96, has 70% of the length of lambda phage DNA. The process of lambda phage-mediated transduction of pKY96 generated a small amount of transducing phage particles containing ColE1-cos lambda DNA molecules of 80 or 101% of the length of lambda phage DNA, in addition to those containing original pKY96 DNA molecules. The newly isolated larger plasmid DNAs were transduced 100 times more efficiently than pKY96 DNA. Their structures were compared with that of a prototype pKY96 DNA, and the mechanism of the formation of these molecules is discussed.

Bacteriophage lambda↗
PubMed1979

Hepatoma with obstructive jaundice due to the migration of a tumor mass in the biliary tract: report of a successful resection.

A 51-year-old man underwent extended right lobectomy for hepatoma of the right lobe with obstructive jaundice due to migration of the tumor mass in the common and bilateral hepatic ducts. Severe jaundice amounting to 32.6 mg% and suppurative cholangitis were relieved by drainage through the cannulation into the hepatic ducts of the bilateral lobes. Although hepatoma was combined with liver cirrhosis, the patient could tolerate extended right lobectomy. The patient is doing relatively well without jaundice 2 years after operation, but a recurrent tumor appeared on the celiac angiogram taken 1 year and 6 months following operation. This is the fourth report on hepatic resection of such cases, and difficult problems involved with that procedure are presented and discussed.

Carcinoma, Hepatocellular↗
PubMed1978

Carcinoma of the proximal bile ducts.

The records of 31 patients with carcinoma of the proximal bile ducts were reviewed and the operative procedures, results, causes of deaths and autopsy findings were analyzed and correlated. Ten poor risk patients were treated by external drainage and died of jaundice or abscesses of the liver within six months. However, one patient survived 13 months after effective bilateral drainage. Twelve patients underwent intubation through the tumor into the hepatic ducts with or without postoperative irradiation. Four patients with irradiation survived 42, 15, 15 and ten months, while eight patients without irradiation died within six months. Autopsy findings of two patients who survived 15 months revealed metastases to the various organs. Four patients underwent resection. A patient who underwent resection of the common hepatic duct and hepaticoduodenostomy died of ascending cholangitis nine months postoperatively, while a patient treated by resection of the common hepatic duct with hepaticojejunostomy died of a recurrence 25 months postoperatively. Two patients underwent left hepatic lobectomy and resection of the right hepatic duct followed by hepatojejunostomy. One patient survived 25 months and died of a reccurrence, while the other patient died of abscesses of the liver ten months postoperatively.

Adenocarcinoma↗
PubMedDate not supplied

Aggressive surgery for pancreatic duct cell cancer: feasibility, validity, limitations.

Pancreatic duct cell cancer is characterized by a low resectability rate and a low long-term survival rate. Between September 1974 and December 1992 in our institution, 149 (59%) of the 253 patients with this cancer underwent resection. The operative procedures were pancreatoduodenectomy in 105 patients, total pancreatectomy in 36, and distal pancreatectomy in 8. The tumor was extirpated with extensive dissection of the lymph nodes and excision of the nerve plexus in the retroperitoneum. Of the 149 patients, 79 (53%) underwent combined resection of the pancreas and the portal vein; 16 of the 79 patients also underwent resection of the adjacent arteries. Three patients died within 30 days after surgery, and 17 other patients succumbed within 2 to 7 months. The mortality among patients undergoing pancreatectomy and resection of the portal vein (9.5%) was similar to that of patients with pancreatectomy alone (10%). Curative resection was necessary for long-term survival. The 5-year survival rate in 61 patients with the curative resection was 15%. Ten patients lived more than 5 years. Even patients with lymph node metastases and cancer invasion of the portal vein had a prolonged survival. Intraoperative irradiation was carried out in 35 patients to improve the survival rate, but without success. Infusion chemotherapy with 5-fluorouracil via the portal vein was tried in 25 patients, resulting in a decrease in liver metastasis. We have made some progress in the first step toward improving treatment, although we are far from the goal and it is necessary to conduct additional trials.

Adult↗