Search PubMedSearch

Biomedical subjects

T Tot

Publications and source records attributed to T Tot.

6 recordsLinked to original sources

[An experimental model of ischemic lesions of the small intestine].

Ischemic (necrotic) lesions of the small intestine are caused by the influence of elevated environment temperature on the rat. The initial change which was gained was a subnuclear vacuolization of the absorptive cells on the tips of the intestinal villi. Later on, the vacuoles blend into the subnuclear space which contains a serous exudate in some places. With the expansion of the subnuclear space the epithelium separates from the stroma, and after it's desquamation there comes to an autolysis of the denuded stroma of the intestinal villi. The lesions are comparable with lesions of the small intestine caused by hypothermia, shock, mesenterial blood vessel ligation in experimental models of other authors, and with ischemic lesions of the small intestine in humans as well. These changes can be considered as a nonspecific consequence of mesenterial ischemia in the appearance of which vascular factors play a key role.

Animals

[Sudden death due to dysplasia of the right ventricle].

The authors present two cases of arrhythmogenic right ventricular dysplasia in two young males, who had died by sudden death. A brief presentation is given of the clinical manifestation, uninvasive and invasive diagnostic possibilities, of the pathoanatomic finding and the pathohistological presentation, and the possibilities of treatment.

Adolescent

[Multiple gastrointestinal polyps].

A case of a ten year old adopted girl is presented, who had gastrointestinal disturbances, anal pruritus and relapses of urticaria from her fourth year of age. By means of radiological and endoscopis analysis, multiple gastrointestinal polyposis was established. Pathohistological examination of the polyp indicated that tubular adenomas were in question, therefore in the case of this girl it can be stated that she has diffuse tubular gastrointestinal adenomatous polyposis, which is a characteristic of Gardner's syndrome. At the moment of the setting of the diagnosis, the girl had no skin changes nor did she have any radiological changes on the bones of her skull. The first skin changes appeared one year after the diagnosis was set, and they were in the form of maculopapular nodules, comedos of the closed and open type on the forehead and chin.

Child

[Characteristics of colonic carcinoma in our material].

By analyzing the characteristics of colonic carcinoma on the ten-year material of the Department for pathology of the Senta Hospital we came to a conclusion that this disease has a greater part in the mortality structure of the region along the river Tisa in relation to the Vojvodina average. Some morphologically prognostic elements (the tumor type, the intensity of peritumoral lymphocytic infiltration) do not show any significant deviations from literature facts, while tumor differentiation, the type of invasion and grading according to Dukes indicate a less favorable situation in our surroundings. An attempt was made to evidence the relation between colonic adenoma and carcinoma on the basis of classic morphology and the presence of nucleolar organizers. Our results indicate the insufficient discovering of precancerous states and early stadiums of colonic cancer in our surroundings.

Adult

[Results of laryngo-microscopic examinations over a 10-year period at the ORL Department of the Senta Hospital].

In the period from 1980-1989, 199 laryngomicroscopical examinations were conducted at our department. There were 20 cases of laryngeal carcinoma, 55 cases of keratosis with the presence of dysplasia in 21.8%, as well as 19 papillomas in adult individuals. In our material keratoses appear a few years before the onset of laryngeal carcinoma in an average statistical distribution. With one exception, the carcinomas were detected before the appearance of metastases. Our data indicate the exceptional benefit of laryngomicroscopy in the detection of precancerous lesions and carcinoma of the larynx.

Adolescent

[Precancerous lesions in the gastrointestinal tract. I. The stomach].

Detection of precancerous lesions and early phases of stomach carcinoma is the basic aim in the fight against this malignant tumour of a very bad prognosis. On the basis of data from contemporary literature, the basic elements of epidemiology and pathology of stomach precancerous lesions are presented in this paper. Chronic gastritis, intestinal metaplasias, dysplasias, chronic stomach ulcer and the state after the stomach resection due to benign disease are dealt with from that aspect. The terms of precancerous states are considered in the introductory part. Through the definition of specific morphological changes general practitioners could be given help in elucidating this problem more successfully.

Humans