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Biomedical subjects

T Tomiyama

Publications and source records attributed to T Tomiyama.

At least 145 records · Page 8Linked to original sources
PubMed1983

The relationship of renal histopathological lesions to immunoglobulin classes and complement fixation of anti-native DNA antibodies in systemic lupus erythematosus.

The relationship of renal immunohistopathological lesions to the immunoglobulin classes (Ig) and complement fixation (CF) of anti-native DNA antibodies (anti-nDNA) in sea was studied in 20 patients with systemic lupus erythematosus (SLE) on whom renal biopsy was performed. The Ig classes and CF of anti-nDNA were assessed by the indirect immunofluorescent and complement fixation methods employing kinetoplasts of Crithidia luciliae as substrate. The histopathologically active lesions of lupus nephritis showed a significant correlation with the IgG and complement fixation of anti-native DNA antibodies in sera. IgM anti-nDNA superiority was not necessarily observed in patients with inactive histological lesions, but rather in those with thickening of the glomerular basement membrane. The granular deposits of immunoglobulin or complement in the renal glomeruli showed a significant correlation with the presence of IgG and CF of anti-nDNA in sera, while the deposition of C3 in the glomeruli also showed a significant correlation with the CF of anti-nDNA.

Adult↗
PubMed1979

Exohemagglutinins: new products of vibrios.

A number of vibrio strains isolated from marine water produced high units of phytohemagglutinin-like agglutinins. Sugar specificity of the hemagglutinins was different from that of the sugar-binding bacterial toxins and that of the sugar-binding pili on the bacterial cell surfaces.

Agglutinins↗
PubMed1975

Passive hemagglutination reaction test using formalinized sheep erythrocytes treated with tannic acid and coated with proteast or elastase of Pseudomonas aeruginosa.

Methods were established for estimating antibodies of protease and elastase of Pseudomonas aeruginosa by passive hemagglutination (HA) tests using fixed sheep erythrocytes coated with each of the two enzymes. High antibody titers of protease and elastase were found in the HA tests on sera in some cases suffered from P. aeruginosa infection. The evaluation of the HA tests was discussed.

Animals↗
PubMedDate not supplied

Assessment of right hepatic artery involvement in patients with biliary tract cancer using color Doppler ultrasonography.

The accuracy of color Doppler ultrasonography (CDUS) in diagnosing right hepatic artery (RHA) involvement was preoperatively evaluated in 28 patients with biliary tract cancer. When a tumor partially or completely surrounded the RHA, the circumferential involvement was diagnosed as positive. With B-mode ultrasonography imaging alone in the 10 nonsurgical patients, the correspondence rates with angiography for the presence of invasion, absence of invasion, and overall were 33%, 0%, and 10%, respectively. However, CDUS allowed clearer visualization of the RHA than did B-mode imaging, and the correspondence rates of CDUS with angiography were 100%, 43%, and 60%, respectively. In the 13 surgical patients, the accuracy levels of B-mode imaging, CDUS, computed tomography, and angiography for the detection of RHA involvement were 46%, 77%, 58%, and 92%, respectively, when compared with surgical and histopathologic findings. Although the accuracy of CDUS was lower than that of angiography, it can be performed repeatedly and noninvasively. CDUS is expected to be useful for the initial assessment of RHA involvement.

Aged↗
PubMedDate not supplied

Safe percutaneous canalization of the biliary tree using a sheath in patients with malignant biliary stenosis.

BACKGROUND: Percutaneous canalization of the bile duct is essential for radiologic interventions of the biliary tract. This study discusses technical considerations for safe approaches for canalization of the bile duct when using a sheath. METHODS: During early and late periods, percutaneous canalization was performed in 104 patients and 79 patients with malignant biliary stenosis, respectively. The late period differed from the early period in that the bile duct was canalized with a previously placed sheath to prevent catheter dislodgement during the procedure. RESULTS: During the early and late periods, catheter dislodgement during canalization occurred in three of 104 patients (3%) and none of 79 patients (0%), respectively. The success rate of canalization without cholangioscopy in the late period (99%) was better than that in the early period (89%; p < 0.05). CONCLUSION: Placement of a sheath into the biliary tree increases the safety and success of canalization in patients with malignant stenosis.

Adult↗
PubMedDate not supplied

Catheter dislodgement of percutaneous transhepatic biliary drainage: identification of role of puncture sites and catheter sheath.

BACKGROUND: To identify the appropriate puncture points in the bile duct to avoid catheter dislodgement. METHODS: Percutaneous transhepatic biliary drainage catheters (n = 300) were placed in 242 patients. The frequency of dislodgement (complete dislodgement or bending of the catheter) was prospectively investigated. The puncture site of the bile duct was classified on the ultrasonographic findings as follows: Main-B3, main branch of the lateral inferior segment; peripheral-B3, peripheral branch of the lateral inferior segment; B2, lateral superior segment; left hepatic duct, proximal portion of the left hepatic duct; B8, anterior superior segment; B5, anterior inferior segment; B5 + 8, main bile duct of the anterior segment; B6, bile duct of posterior inferior segment; and right hepatic duct, proximal portion of the right hepatic duct. RESULTS: When a catheter without an outer sheath was used, catheter dislodgement in peripheral-B3 (2/11, 18%) was more common than in main-B3 (0/32, 0%; p < 0.05). In B5, catheter dislodgement (6/12, 50%) was more frequent than in B8 (3/20, 15%; p < 0.05) and in B6 (0/14, 0%; p < 0.005). When a catheter with an outer sheath was used, catheter dislodgement (2/207, 1%) was rare. CONCLUSION: Drainage from B5 and peripheral-B3 is associated with a high risk of dislodgement of the catheter. A catheter with an outer sheath was useful to prevent catheter dislodgement.

Adult↗
PubMedDate not supplied

Hyperechoic lines as a sonographic confirmatory sign during percutaneous transhepatic biliary drainage.

BACKGROUND: In ultrasonically guided percutaneous transhepatic biliary drainage, we often can recognize hyperechoic lines at the tip of the needle when the duct is penetrated successfully. We evaluated the frequency of this phenomenon and analyzed whether it was a useful sign for confirming successful bile duct puncture. METHODS: In 65 patients with biliary tract diseases, 84 catheters were placed in the course of 108 attempts at puncture. Results of puncture and the presence of hyperechoic lines were investigated prospectively. RESULTS: When the ultrasonographic findings showed hyperechoic lines, successful puncture was significantly more frequent than when the findings did not show hyperechoic lines (53/55, 96%, vs. 31/59, 53%; p < 0.0001). When we judged the hyperechoic lines as the sign of successful puncture, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 63%, 93%, 96%, 48%, and 71%, respectively. CONCLUSION: Hyperechoic lines are a useful confirmatory sign of successful puncture. However, absence of these lines was not invariably associated with unsuccessful puncture.

Aged↗