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Biomedical subjects

T Thrasher

Publications and source records attributed to T Thrasher.

5 recordsLinked to original sources
PubMed1989

Fallopian tube carcinoma: a clinicopathological study of 17 cases.

From 1969 through 1986, 17 patients with primary adenocarcinoma of the fallopian tube were treated at the Loma Linda University Medical Center. Stages I, II, and III of the disease were present in 6, 5, and 6 patients, respectively. The mean age of the patients was 59.9 years. Vaginal bleeding or discharge (57%), followed by abdominal pain or discomfort (29%), was the most common symptom in our patients. A palpable pelvic mass was detected in two-thirds of the patients. One case of carcinosarcoma, one case of mixed mesodermal tumor, and one case of endometrioid carcinoma are included. No patient in this series had a correct preoperative diagnosis. Therapy consisted of surgical resection, usually followed by various combinations of adjuvant radiation therapy and/or chemotherapy. The overall 5-year survival rate was 31%. Five patients (29%) are alive without evidence of disease. This study supports the need for collaboration among large centers to define the optimal adjuvant therapy of this disease. In the absence of the desired treatment protocols, such lesions should be approached in a manner similar to that used for ovarian cancers.

Adenocarcinoma↗
PubMed1988

Focal intestinal heating with regional abdominal hyperthermia.

The effect of regional abdominal heating on the small and large bowel was evaluated in three female research pigs. The BSD Annular Phased Array was used for heating. Blind-end catheters and a free peritoneal probe were surgically attached to small bowel, large bowel, liver, and kidney. Each pig underwent 4-8 heating sessions and was subsequently autopsied. There was no histologic evidence of acute bowel, liver, or kidney damage. There were significant differences in temperatures at the various sites. The average small bowel temperature was significantly higher than predicated by the free peritoneal probe or than seen in the liver or kidney. The large bowel temperatures averaged higher than the free peritoneal probe temperatures, but the difference was not significant. Liver and kidney temperatures approximate whole body temperature due to extensive vascular network. Although the elevated small bowel temperatures may be due in part to different position in relation to isotherms, the frequent occurrence of a large temperature difference suggests focal heating of fluid pockets in the small bowel.

Abdomen↗
PubMed1984

Microinvasive squamous carcinoma of the vulva: present status and reassessment.

A retrospective analysis of 24 patients with early invasive squamous carcinoma was performed. No nodal metastases were noted in these patients. Based on a review of the literature, no absolute definition of microinvasive carcinoma could be formulated, but a treatment outline has been formulated based on depth of invasion for Stage I lesions.

Adult↗