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Biomedical subjects

T Tanigaki

Publications and source records attributed to T Tanigaki.

50 records · Page 3Linked to original sources
PubMed1984

A case of epidermodysplasia verruciformis (Lewandowsky-Lutz, 1922) with skin cancer: histopathology of malignant cutaneous changes.

Histopathology of tumors which occurred on the face of a 34-year-old man with epidermodysplasia verruciformis was studied. The following three different types of histological changes were recognized in the tumors: (1) intraepidermal initial changes; (2) Bowen-like changes, and (3) squamous cell carcinoma. Carcinogenetic processes in this case were compatible with those reported by Todaro et al. in 1966, in which case tumors were caused in vitro by SV40 virus. According to their results, initial transformed cells were observed to occur at the lower layer of the epidermis. It seemed likely that viral infection occurred at the epidermal lower layer and immediately the infected cells divided and some of them changed to transformed cells which then abnormally proliferated to show a malignant feature. Similar histological changes were recognized and viral oncogenesis was suggested in this case too.

Adult↗
PubMed1982

New human papilloma virus isolated from epidermodysplasia verruciformis lesions.

Human papilloma virus (HPV) was isolated from red plaques of a patient (N. F.) with epidermodysplasia verruciformis. Electron microscopic examination showed characteristic particles of papilloma virus as icosahedrons about 45 nm in diameter. DNA was extracted from these particles, and closed-circular DNA (Form I) was purified by centrifugation in CsCl containing ethidium bromide. The molecular weight of the DNA was about 5.0 x 10(6). A physical map of the HPV DNA was constructed using several restriction enzymes. The restriction endonuclease cleavage pattern of the HPV DNA was different from those of other types of HPV reported thus far, suggesting that the isolate was a new, as yet unclassified, HPV.

Adult↗
PubMedDate not supplied

Massive hemoptysis due to Mycobacterium fortuitum infection controlled with bronchial artery embolization - a case report.

We reported a case of first reported pulmonary infection due to Mycobacterium fortuitum (M. fortuitum) with massive hemoptysis, successfully treated by bronchial artery embolization (BAE). A 78-year-old male was admitted to our hospital complaining of massive hemoptysis. A biochemical examination and DNA/DNA hybridization revealed M. fortuitum in the culture of his sputum. He was treated by BAE, and antituberculous agents and levofloxacin. The patient remains well without recurrence more than one and a half years after the admission.

Aged↗
PubMedDate not supplied

Long-standing hiccup in a patient with sarcoidosis.

The patient was a 67-year-old male. A diagnosis of sarcoidosis was made both by transbronchial lung biopsy and by scalene node biopsy. The findings of his chest roentgenogram were categorized as the group II. There were no symptoms during follow-up period of one year at the out-patient clinic with no medication. The chest X-ray findings of the patient were slowly progressive. Intractable hiccup developed one year after his first visit to the hospital. With administration of prednisolone, serum angiotensin converting enzyme level decreased promptly, and the incidence of the hiccup attack decreased. As the dose of prednisolone was tapered, the hiccup recurred. All the drugs used for hiccup including quinidine sulfate and metoclopramide was not effective. A thoracic CT revealed slight enlargement of mediastinal lymph nodes. A brain CT and a brain MRI demonstrated no abnormalities. Acetazolamide, which induces acidosis in brain extra-cellular fluid, worsened the symptoms. As prednisolone was given again, infiltrates on the chest roentgenogram began to resolve and the incidence of hiccup decreased. We concluded that the long-standing hiccup observed in this patient may be brought by the lesion in central nervous system due to sarcoidosis.

Aged↗