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Biomedical subjects

T Takemiya

Publications and source records attributed to T Takemiya.

33 records · Page 2Linked to original sources
PubMed1985

[Time-dependent measurement of differential digital plethysmogram in bicycle ergometer exercise].

Time-dependent measurements of differential digital plethysmogram during exercise were made on five male subjects. The results obtained were as follows; Differential digital plethysmogram (delta DPG) was obtained by using biophysical amplifier with the time constant of 0.03 seconds which minimized the fluctuation of the baseline in digital plethysmogram (DPG). A linear relationship was shown in P wave amplitude of both delta DPG and DPG. The decrease in delta DPG-P waves was observed in visual concentrations, mental learning and arithmetic, initial inspiratory phase with tachycardia, maximal inspiratory and/or expiratory breath holding, and head-up tilt at 60 degrees or over. The increase in delta DPG-P waves was obtained at the expiratory phase with bradycardia and in the effect of alcohol intake. During 15 minutes of bicycle ergometer exercise at 750 kpm/min, the P wave amplitude in delta DPG decreased to 77% of the control in the first one minute of exercise, and then gradually increased to 218% at the final stage of exercise (p less than 0.01). Heart rate measured simultaneously increased, as compared from the beginning of exercise. P wave amplitude and heart rate after exercise decreased progressively to the control level. It is suggested that the initial decrease in P wave amplitude of delta DPG couples with the dominant activity of the sympathetic vasoconstrictor, and the final increase in P waves is due to the compound factors of the increased cardiac output and arteriolar vasodilation.

Adult↗
PubMed1984

[An acute syndrome of opsoclonus and body tremulousness. A case report of benign encephalitis].

A 30-year-old woman was admitted to our hospital in May 1977, suffering from oscillation, body tremulousness and astasia-abasia. Two months prior to admission she had caught a common cold and felt paresthesia on the right arm. Three days before admission, she had photophobia, tremulousness of the trunk and head, and astasia-abasia. A neurological examination revealed difficulty in standing, and jerky movement of the body and right arm, her limbs were well coordinated. An ocular examination resulted in normal findings except for intermittent oscillation of the eyeballs. As the pupils and fundi were normal, so were the routine laboratory tests. The cerebrospinal fluid was clear and colorless under normal pressure, and showed no more than 6 mononuclear cells in any of the three examinations. CSF protein was registered 20 mg/dl, glucose 75 mg/dl, and no virus titers were elevated. Electroencephalogram was slightly abnormal due to a slowing of the Alpha wave in the background activity. Both computerized tomography and vertebral-angiography were normal. A slow and steady abatement of all symptoms started while she was taking steroid treatment in hospital. Electrooculogram showed irregular disconjugation of the eyes rotating or moving in horizontal and vertical direction. There movements conjugated or disconjugated in both eyes with 5-7 Hz of frequency and 10-20 degrees of amplitude. They decreased when the eyelids were closed or staying in a dark room. These ocular movements were regarded as opsoclonus. Then opsoclonus changed to flutter-like oscillation.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1983

[Central pontine myelinolysis--pathogenesis and review of the literature].

A 77-year-old, nonalcoholic man was admitted to the Omiya Red Cross Hospital with the complaint of fever and delirium state of two days' duration. Two months prior to admission he had had cough and sputum. Chest X-ray revealed honey comb lungs. Cultures of sputum revealed mycobacterium tuberculosis after eight weeks incubation. He had no liver disease in his past history. The patient appeared cachetic. His vital signs were as follows; temperature 38 degrees C, blood pressure 132/68 mmHg, with a pulse rate of 84/min. He was delirium and excited. Findings of the cranial, motor and sensory nerve examination were normal. Initial laboratory studies showed a serum sodium value of 133 mEq/l, potassium 4.5 mEq/l, chloride 98 mEq/l; a serum GOT value of 51 units, GPT 36 units; a total protein content of 7.8 g/dl and ESR rate of 87 mm/hr. Six days after admission, the patients' consciousness level began to stupor and nuchal rigidity was appeared. Spinal fluid examination revealed opening pressure 270 mm H2O, cell counts 720 (N 712, L 8)/cumm, sugar 57 mg/dl and protein 170 mg/dl. Spinal fluid cultures were positive in mycobacterium tuberculosis after eight weeks incubation. Laboratory studies showed a serum sodium value of 114 mEq/l, potassium 4.4 mEq/l, chloride 86 mEq/l, a serum osmorality (SeOs) 225 mOsm/l and urine osmorality (UOs) 958 mOsm/l.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗
PubMedDate not supplied

Effects of dilevalol in hypertension assessed by digital pulse plethysmography.

For two weeks, with the exception of one case involving long-term therapy, 15 hypertensive patients received 100 mg of dilevalol once daily and seven patients received 50 mg. Blood pressure and heart rate were measured and digital pulse plethysmography (DPG) was performed before and after the two-week trial. Systolic and diastolic blood pressure decreased significantly during treatment; heart rate did not change. There were also significant changes on the three DPG measures of vasodilatation: peak amplitude increased, the dicrotic index decreased, and peak amplitude on the differentiated DPG increased. A weak correlation was found between the changes in systolic blood pressure and changes in the two measures of DPG peak amplitude. It is concluded that dilevalol is effective in the treatment of hypertension and that DPG is a sensitive noninvasive method to measure vasodilatation.

Adult↗
PubMedDate not supplied

Somatosensory evoked potentials following voluntary movement during upper arm compression.

We examined the modulation of somatosensory evoked potentials (SEPs) during upper arm compression and following voluntary movement during upper arm compression. Most SEPs were significantly decreased, although some SEPs showed a slight, non-significant diminution. SEPs are mediated not only by myelinated fibers but also by mixed nerves and afferents from cutaneous, joints, and deep tissues, these being dependent upon the dorsal column-medical lemniscal system. Therefore, most of the diminution in SEPs found here may have been due to afferent occlusion from muscle, cutaneous, joints, and deep tissues, since normal SEPs are selectively modulated, corresponding to motor or mental tasks, regardless of whether gating is centrifugal or centripetal. In addition, the present experiments showed that all the SEPs at FZ, C3' and CZ were significantly decreased following voluntary movement at a pressure 25%-30% higher than the subject's systolic blood pressure. Comparing SEPs during upper arm compression and those following voluntary movement during upper arm compression at these pressures, we found that the SEPs at C3' were significantly diminished following voluntary movement during upper arm compression, with other SEPs showing slight, non-significant attenuation. In conclusion, it is possible that the diminution in SEPs following voluntary movement could be responsible for sensory inputs, however, when sensory inputs are present, centrifugal modulation would also be responsible for this diminution.

Adult↗