[Hormonal changes and physical growth in boys aged 7.5 to 15 years (author's transl)].
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Biomedical subjects
Publications and source records attributed to T Taguchi.
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Aortic specimens from 111 autopsy and 23 surgical cases were examined by light and electron microscopy. Differential mast cell counts were made of three aortic segments (ascending, thoracic, and abdominal) and layers (intimal, medial, adventitial). The mast cell counts varied considerably from case to case and sector to sector and generally showed no correlation with age, sex, or atherosclerotic severity. However, intimal mast cells were fewer in number in areas of lipid accumulation than in areas of diffuse intimal thickening without lipid accumulation. The reduction in the number of intimal mast cells may play a part in the localization of atherosclerosis.
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Two patients had two recurrent episodes each of acute suppurative thyroiditis. Circulating concentrations of plasma thyrotrophin, thyroxine, and triiodothyronine were within the range of normal. Antibodies to thyroid microsome or thyroglobulin were not found. Anaerobic bacteria such as Bacteroides, Peptostreptococcus, and Peptococcus were identified as causative agents, indicating that anaerobic organisms may play an important role in the pathologic process. The present cases are the third and fourth reported cases of recurrent acute suppurative thyroiditis in the literature.
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47 renal biopsies from 36 patients with SLE were examined in detail to compare with clinical courses and ultrastructural findings. Of 36 patients, 8 cases were free from renal involvement. The severity of electron dense deposits in glomeruli with lupus nephritis were generally well correlated with each clinical feature obtained. Moreover, mesangiocapillary cell proliferation was considered to be the main morphological promoting factor in poor prognosis of the lupus nephritis. Prominent circumferential subendothelial dense deposits were suggested to enhance to enhance the proliferation of mesangial cells, mostly with a mode of circumferential interposition. In each deposit with lapse of time and/or treatments, subepithelial deposits were gradually degraded to granular material but not lucent, though most subendothelial deposits rapidly disappeared without any remnant structure or with only a few flocculent materials. Mesangial deposits were mostly stabilized and rarely turned membranous.
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Isozyme pattern of pyruvate kinase in the liver of nude mice bearing Ehrlich ascites tumor changed markedly during tumor growth. The change in isozyme pattern of pyruvate kinase was not due to infiltration or metastasis of tumor cells in the liver. Such a change in isozyme pattern of pyruvate kinase was also found in the liver of nude mice bearing canine gastric leiomyosarcoma induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), but not in the liver of nude mice bearing MNNG-induced canine gastric adenocarcinoma or human gastric adenocarcinoma.
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