Biomedical subjects

T T Su

Publications and source records attributed to T T Su.

20 records · Page 2Linked to original sources

PubMed1978

Synthesis of spirofluorenes of biological interest.

1'-Substituted spiro[fluorene-9,3'-pyrrolidine-2',5'-diones], 1',1''' - (1,4-piperazinediyldimethylene) bis[spiro[fluorene-9,3'-pyrrolidine-2',5'-dione]], and 1'-arylspiro[fluorene-9,3'-pyrrolidines] were synthesized from spiro[fluorene-9,3'-tetrahydrofuran-2',5'-dione]. The rat passive cutaneous anaphylaxis assay showed that one compound possessed slight antiallergic activity. Synthesis of 3-substituted 1-aryl-4-oxospiro[azetidine-2,9'-fluorenes] and 1,1''-p-phenylenebis[4-oxospiro[azetidine-2,9'-fluorenes]] was achieved via the reaction of appropriate N-fluorenylideneanilines with tert-butylcyanoketene and cyclopentamethyleneketene, respectively.

Animals↗

PubMedDate not supplied

The regulation of cell growth and proliferation during organogenesis.

Both growth (increase in mass) and proliferation (increase in cell number) contribute to the formation of multicellular organisms. We would like to understand the mechanisms that normally regulate growth and proliferation because breakdown of these mechanisms may be the basis for uncontrolled growth and proliferation that are associated with cancerous transformation and tumor progression. We review here classical and recent literature from diverse experimental systems that pertains to the regulation of mass and cell number.

Animals↗