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Biomedical subjects

T T Pessi

Publications and source records attributed to T T Pessi.

12 recordsLinked to original sources

Nitrogen-calorie ratio during total parenteral nutrition in 1001 surgical patients treated in intensive care unit.

Nitrogen-calorie (non-nitrogen) ratio during total parenteral nutrition in 1001 successive surgical patients treated in intensive care unit of Tampere Central Hospital over two and a half years was studied. The mortal was three percent in the patients (N = 222) needing only intensive observation, seven per cent in the group (N = 544) needing intensive treatment and 54 per cent in the patients needing intensive therapy (N = 287). Complete parenteral nutrition was only one aspect of the total intensive treatment and it was fulfilled in harmony with the other forms of treatment to safe the life of these critically ill patients. Thus e.g. the clinical status, blood circulation, respiratory function, renal function, blood gas, blood glucose concentration, diuresis and excretion of urea were followed. Complete parenteral nutrition by 15 per cent fructose-glucose solution, 20 per cent fat emulsion (Intralipid), and/or aminoacid solution (Levamin forte, 1000 ml = 11 grams amino-nitrogen and 400 kcal) was given to 87.6 per cent of the patients for 3717 days of treatment. The results showed that nitrogen-calorie ratio during total parenteral nutrition in 1001 surgical patients treated in intensive care unit was 1:125, indicating a low amount of energy given for each gram of administered nitrogen. The nitrogen-calorie ratio for the patients who needed only intensive observation, intensive treatment or intensive therapy were: 1:112, 1:130 or 1:121, respectively.

Energy Intake

The intensive care of acute pancreatitis.

The results of medical and surgical treatment of 115 cases of acute pancreatitis treated in the surgical intensive care unit over a period of 8 years are reviewed. The death rate from acute pancreatitis fell during the period of study in the intensive care unit from 42.6% between 1969 and 1973, when drainage was used, to 22.9% between 1974 and 1976 when resection was performed, and in hospital from 8.2% to 5.8% respectively. The results improved as a consequence of adequate treatment of shock, complete intravenous feeding, accurate timing of surgery and the successful choice of operative procedures.

Acute Disease

Massive resection of the small bowel.

A report is presented on patients (no. = 43. 64 +/- 9 years, 30 men and 13 women) subjected to a massive small bowel resection (69 +/- 25 cm intestine left). The most usual indication was thromboembolism of the arteria mesenterica superioris, but there were also patients who had had intestinal by-pass, occlusion, trauma, tumor and invagination. The preoperative diagnosis was based on peritonitis, increasing abdominal symptoms, paralytic ileus, shock and fever. Fluid and electrolyte treatment, postoperative intensive care, intestinal decompression, parenteral nutrition and antibiotics were also employed. Postoperatively there was a significant decrease in serum protein (SP) (63 +/- 11 vs. 43 +/- 9 g/l) and blood hemoglobin (150 +/- 10 vs. 106 +/- 8 g/l) concentrations (Hb) and hematocrit (CHCT) (0.44 +/- 0.11 vs. 0.31 +/- 0.10). Also the number of patients with subnormal SP and Hb increased from five to nineteen and from fourteen to thirty-two, respectively. The operative mortality (within 30 days) was 60 percent (26/43). Those who survived were younger (59 +/- 8 vs. 67 +/- 9 years) and had higher SP (87 +/- 12 vs. 47 +/- 11 g/l), blood leukocyte count (22 +/- 6 vs. 14 +/- 5 X 10(9] and lower peroperative blood loss (291 +/- 43 vs. 448 +/- 67) than those who died. During the one to 14 year follow-up time nine (21% of all patients and 59% of those who were discharged) were still alive. Thus the patients subjected to a massive small bowel resection are old, have atherosclerotic cardiovascular diseases and preoperatively have peritonitis or severe abdominal complaints and an impaired nutritional state and fluid balance.

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