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Biomedical subjects

T Sueda

Publications and source records attributed to T Sueda.

At least 19 recordsLinked to original sources

Effect of venous valves on grafts for coronary artery bypass.

The effect of venous valves on blood flow and patency in grafts of the long saphenous vein for coronary artery bypass is examined. Our experimental model involved both diastolic-predominant blood flow and transient systolic regurgitation, and the waveform was similar to that of in vivo coronary circulation. In this model, blood flow was assessed in the presence or absence of venous valves. It was found that coronary artery blood flow was significantly greater in the presence of venous valves. Angioendoscopy showed that the movement of the graft valves was strong and rhythmic. It seems that valve preservation may be desirable in grafts for coronary artery bypass.

Angiography

Renal artery aneurysm: the significance of abdominal bruit and use of color Doppler.

A case of renal artery aneurysm is presented. The patient had no hypertension and no signs of arteriosclerosis obliterans or aortitis syndrome, except for abdominal bruit. A saccular aneurysm, 1 cm in diameter, was demonstrated by two-dimensional and color Doppler ultrasound and documented by angiography. The aneurysm was embolized by a steel coil. The abdominal bruit, though uncommon, is a very important bed-side sign of renal artery aneurysm, if the patient exhibits no arteriosclerosis obliterans or aortitis syndrome. Ultrasound Doppler is very useful in screening for aneurysm.

Aneurysm

Comparative study of cerebral protection during surgery of thoracic aortic aneurysm.

During the past 5 years, 30 cases of thoracic aortic aneurysm were treated. Selective cerebral perfusion (SCP) and retrograde cerebral perfusion (RCP) were conducted for cerebral protection during aortic cross clamping. SCP was carried out in 5 cases of dissecting aneurysm (all Stanford type A, including a case of AAE) and 3 cases of arch aneurysm. RCP was conducted in 5 cases of dissecting aneurysm (4 Stanford type A, 1 Stanford type B with retrograde dissection) and 2 cases of aortic arch aneurysm. The mean cerebral perfusion time of SCP exceeded that of RCP (89 +/- 26 min in SCP versus 61 +/- 33 min in RCP p < 0.05). The hospital mortality rate was 38% (SCP) and 29% (RCP). Neurological complications were prolonged unconsciousness (1/8 in SCP, 1/7 in RCP) and transient paralysis (0/8 in SCP, 1/7 in RCP). Although the mechanism for the cerebral protective effect of RCP is unknown, this perfusion method is easy and safe, requiring little time for ascending and/or arch aortic reconstruction.

Aged

[A case of rectus sheath hematoma].

The following is a rare case of rectus sheath hematoma. The patient was a 78-year-old man with a past history of axillo-femoral bypass operation. He contracted a cold, and when he coughed severely, acute lower abdominal pain occurred. Abdominal echography and CT scanning confirmed the presence of a hematoma in the rectus abdominis muscle. Before, patient was diagnosed as acute abdomen and surgery was performed. Recently, accurate diagnosis has been made easily by echography or CT.

Abdomen, Acute

Protection by coenzyme Q10 of canine myocardial reperfusion injury after preservation.

This study was undertaken to assess whether pretreatment of the donor heart with coenzyme Q10 could improve postischemic myocardial recovery. Coenzyme Q10 or its solvent was administered intravenously to donor dogs 1 hour before isolation of the heart. Each heart was stored in Euro-Collins solution at 4 degrees C for 6 or 24 hours and then was reperfused via the aorta with arterial blood of a supporting dog for 3 hours at 37 degrees C in a working mode. During preservation, adenosine triphosphate level was significantly reduced in the placebo group from 21.0 mumol/gm dry weight to 15.1 and 11.9 after 6 and 24 hours of preservation, respectively. Coenzyme Q10 pretreatment maintained the adenosine triphosphate level at 18.9 even after 24 hours of preservation. After reperfusion following 6 and 24 hours of preservation, the adenosine triphosphate level recovered to the original level in the coenzyme Q10 group, but it remained significantly low in the placebo group. Preservation and subsequent reperfusion caused a significant increase in the level of malondialdehyde of hearts in the placebo group, and coenzyme Q10 pretreatment completely suppressed the increase in the malondialdehyde level after reperfusion. Ventricular functions were improved in the coenzyme Q10 group. These results support the concept that free radicals play an important role in myocardial injury during preservation and subsequent reperfusion and suggest that pretreatment of the heart with coenzyme Q10 is effective in preventing such injury that may develop after reperfusion.

Adenosine Triphosphate

[A case of infective endocarditis of the tricuspid valve repaired by vegetectomy and annuloplasty].

A successful repair of infective endocarditis of the tricuspid valve in a drug abuser is reported. A 25-year-old woman with a history of drug addiction was referred to our hospital complaining of high fever despite antibiotic therapy. Blood cultures showed staphylococcal septicemia, and echocardiography revealed large vegetations attached to the tricuspid annulus and massive regurgitation of the tricuspid valve. Blood studies showed renal failure and hematological abnormalities due to septicemia and right ventricular failure. Excision of the vegetation and the posterior leaflet was performed along with annuloplasty (Kay's procedure). The patient's postoperative course was uneventful and subsequent echocardiographic examination disclosed no evidence of recurrence, and insignificant tricuspid valvular regurgitation. Local excision of vegetation and leaflet repair by annuloplasty may be performed in cases with well-circumscribed vegetation and minor leaflet damage.

Adult

Surgical repair of Wolff-Parkinson-White syndrome complicated with myocardial bridging.

Myocardial bridging causes myocardial ischemia during supraventricular tachycardia. We present a case of Wolff-Parkinson-White syndrome combined with myocardial bridging. The patient complained of angina pectoris during paroxysmal supraventricular tachycardia because of severe constriction of the left anterior descending coronary artery during systole. A myocardial scintigram revealed myocardial ischemia in the anteroseptal wall during paroxysmal supraventricular tachycardia. Myotomy to prevent myocardial bridging and interruption of the accessory conduction pathway was successfully accomplished in a one-stage operation.

Adult

[Percutaneous transvenous mitral commissurotomy in managing rheumatic mitral stenosis].

From April 1987 to October 1989, 32 patients with mitral stenosis (MS) were treated, of whom percutaneous transvenous mitral commissurotomy (PTMC) was performed in 14. PTMC was indicated by the surgeons in 5 patients including 1) 2 patients who refused reoperation, 2) one with early gastric cancer, 3) one with severe hyperthyroidism and cardiac cachexia, and 4) one with acute renal failure and aortic stenosis. In the other 9 patients, PTMC was indicated by the cardiologists, because it is less invasive. Thirteen patients underwent open mitral commissurotomy (OMC) and 5 patients were treated with mitral valve replacement (MVR). PTMC group: Symptoms were alleviated in 10 of 14. The mitral valve areas (MVA) changed from 1.03 +/- 0.47 cm2 to 1.90 +/- 0.67 cm2 (p < 0.001), and the mean pressure gradient between the left atrium and left ventricle decreased from 10.2 +/- 3.6 mmHg to 4.9 +/- 1.7 mmHg (p < 0.001). No significant mitral valve regurgitation (MR) was induced by PTMC. OMC group: Symptomatic improvement was observed in all patients. The MVA changed from 1.54 +/- 0.46 cm2 to 3.06 +/- 1.34 cm2 (p < 0.001) and the mean left atrial pressures were reduced from 17.6 +/- 7.8 mmHg to 10.5 +/- 4.2 mmHg (p < 0.001). MVR group: There was one hospital death, and the other 4 patients were discharged with satisfactory results. It is concluded that although PTMC has been routinely performed for mild cases, this method is also very helpful in treating patients having various complications which impede open heart surgery.

Adult

WPW syndrome complicated by another cardiac disorder.

During the past 28 months, 16 cases of WPW syndrome were operated on at Hiroshima University Hospital. Two cases were complicated by other cardiac disorders which accelerated tachycardia, making diagnosis difficult. One of these cases showed serious mitral regurgitation, due to infective endocarditis and the patient suffered cardiac failure accompanied by paroxysmal tachycardia not responsive to medical therapy or cardioversion. A complex rhythm with atrial fibrillation and antegrade conduction rhythm through the accessory pathway made diagnosis and therapy quite difficult. The condition of the other patient was associated with myocardial bridging which caused angina pectoris during paroxysmal tachycardia. Myocardial scintigraphy showed myocardial ischemia in the antero-lateral area of the left ventricle. In the former case, mitral valve replacement and interruption of the accessory pathway were undergone simultaneously. In the latter case, myotomy of the muscle on segment 7 was conducted, following interruption of the accessory pathway.

Adult

A centrifugal pump for graft replacement of the descending thoracic or thoraco-abdominal aorta.

Between January 1987, and December 1988, 14 cases of descending thoracic or thoraco-abdominal aortic aneurysm underwent operation using a prosthetic graft replacement. In order to avoid hypoperfusion to distal organs and proximal hypertension during aortic cross-clamping, two different adjuncts were used and the effectiveness of those methods were compared according to the results of surgery. Seven patients were treated with a temporary shunt of heparin-bonded tube from the left axillary artery to left femoral artery, or else Dacron vascular prosthesis from right axillary artery to right femoral artery (Group I). In Group II (seven patients), left heart bypass was performed, using a centrifugal pump from the left atrium to the left femoral artery with minimal heparinization. In Group I, there were two hospital deaths, due to respiratory and hepatic failure respectively, and paraplegia has occurred in one case. In Group II, there was no death during a post-operative observation period of 5-15 months, and there was no case of paraplegia. We think that temporary left heart bypass with a centrifugal pump seems to be the most useful method today for graft replacement of the descending thoracic or thoraco-abdominal aorta.

Adult

[Assessment of alveolar bone changes with gamma-ray absorptiometry--on the analysis of detectability of a measuring system].

It is important to determine the changes in alveolar bone during periodontal treatments. At present, radiography is widely used to determine the changes. But small changes in alveolar bone cannot be detected on X-ray films. To detect these small changes, a direct observation system using gamma-ray from 133Ba was considered. Using a multi-channel analyzer, gamma-ray absorption through the bone was detected in this method. This method was compared with densitometric measurement on the films using sliced animal bone. The newly developed method detected the bone changes more accurately. To evaluate the influence of soft tissue, Mix-D was used in both measurements. 133Ba absorptiometry showed that soft tissue did not influence the measurement more than the densitometric method.

Absorptiometry, Photon

Pocket depth reduction by tooth types and sites after initial treatment.

Differences in pockets depth reduction rates were compared between different tooth types and sites after initial treatment in 41 adult periodontitis patients whose O'Leary plaque records were maintained at less than 10% during initial treatment. Pocket depths were significantly reduced after initial treatment. Response to treatment was good at 15, 25, 14, 24, 33, 43, 31, 41, 34 and 44; but was poor in 11, 21, 17, 27, 37 and 47. Response to treatment was poor on the mesiopalatal surfaces; midpalatal surfaces of 16 and 26; the distolingual surfaces of 17, 27, 37 and 47; and the mesiopalatal surfaces of 11 and 21; but was good on the distobuccal and midpalatal surfaces of 14 and 24, the mesio- and distal-buccal surfaces of 15 and 25; and the mesiolingual surfaces of 34 and 44. The tooth types and root surfaces that require careful attention during treatment were clarified.

Adult

[Nonischemic ventricular tachycardia with coronary arterio-venous fistula].

A 22 year-old man who suffered ventricular tachycardia (VT) during 8 years was admitted to our hospital for treatment of VT. He also had diseased, coronary arterio-venous fistula with a mild L-R shunt and coronary fistula was closed operatively 4 years ago because it was presumed to be a cause of VT, but the VT remained after the closing on the fistula. After admission in our hospital, catheter endomyocardial mapping and coronary cineangiography were undergone and revealed that the coronary artery was intact and a pre-excitation area located in the LV apico-lateral wall. Dual catheter ablations were attempted but resulted in failure. Then, surgical cryoablation was employed under the use of extracorporeal circulation, following epicardial and endocardial mapping. Cryoablation (-150 degrees C) to the postero-septal wall of LV could terminate VT completely.

Adult

[Simultaneous operation of WPW syndrome combined with mitral regurgitation caused by infective endocarditis].

A case of WPW syndrome combined with mitral regurgitation caused by infective endocarditis underwent surgical division of accessory pathway and mitral valve replacement preserving posterior leaflet simultaneously. A 56-years old woman suffered atrial fibrillation with pseudo VT and cardiac failure caused by mitral regurgitation. Electro-physiological study (EPS) revealed accessory pathway in postero-lateral wall in left atrium and atrio-fascicular pathway like James bundle in AV node. ECHO cardiography showed mitral valve prolapse and severe regurgitation. Accessory pathway was divided surgically and deep freeze coagulation was followed. Perforation of anterior leaflet and chordal rupture of posterior leaflet caused by infective endocarditis were repaired by annuloplasty (Kay and McGoon method) at first, but regurgitation retained moderately. After re-clamping of aorta, mitral valve was replaced with prosthesis (SJM 29 mm) preserving posterior leaflet. Postoperative examination revealed division of accessory pathway and no regurgitation of mitral prosthesis.

Endocarditis, Bacterial

A heterotopic cardiac transplantation model for evaluation of rejection using transvenous endomyocardial biopsy.

A model of heterotopic cardiac transplantation for diagnosis of rejection is described. Heterotopic cardiac transplantations were performed in the thorax using the left innominate artery as an arterial supply with venous return into the superior vena cava. Six pairs of mongrel dogs underwent cardiac transplantation using this technique. Two dogs died postoperatively on the 2nd and 3rd day due to respiratory failure. Another four donor hearts arrested their beats in 6 to 8 postoperative days (mean 6.3 days) resulting from acute cardiac rejection. Serial echocardiographic recordings were found to be a reliable measure of acute cardiac rejection, since the left ventricular wall thickness of the donor heart increased until the donor heart stopped by rejection. Endomyocardial biopsy was easy to perform by passage of flexible cardiac biotome into the right ventricle of the donor and the recipient heart through the right internal jugular vein. Pathological findings revealed that early changes of the donor heart were interstitial edema caused by myocardial ischemia. This was followed by lymphocyte infiltration around peripheral coronary arteries and acute rejection resulting in myocyte necrosis.

Animals

[Influence of residual plaque score during initial treatment on pocket reduction rate at individual tooth surfaces].

The purpose of this study is to examine the relation ship between residual plaque score at an individual tooth surface during initial treatment and the pocket reduction rate at the evaluation time. Thirty-nine adult periodontal patients (mean age 30.2 years) who O'Leary plaque control record (PCR) reached a level of 10% PCR, were selected for this study. A total of 5638 surfaces were monitored by recording probing pocket depths at the disto-buccal (a), mid-buccal (b), mesio-buccal (c), disto-lingual (d), mid-lingual and (e), mesio-lingual (f) regions, and by examining O'Leary plaque control records. The results were as follows: 1) The residual plaque score at all teeth surfaces was 14.74 +/- 19.21%. 2) The lowest plaque score were seen at 54/45, and 21/12. 3) The highest plaque score were seen at 7/7, and 76/67. 4) Well-responding sites that showed a high residual plaque score and a good pocket reduction rate, were 5/5 (initial probing pocket depth 3.0-3.5mm, a), and 4/4 (initial probing pocket depth 3.0-3.5 mm,f; 5.0-5.5 mm, f). 5) 7/7 (initial probing pocket depth 3.0 mm a, b, d), and 7/7 (initial probing pocket depth 3.0-3.5 mm, f) showed a high residual plaque score and a low pocket reduction rate. 6) The normal pocket response occurred at a level of residual plaque score and a low pocket reduction rate. 6) The normal pocket response occurred at a level of residual plaque score of less than 25%. In order to gain good pocket response, it is important to keep the level of residual plaque score at less than 25% rather than to keep the level of PCR at 10% or 20% (as several authors have previously stated). 7) A low residual plaque score during treatment is therefore more important than a low PCR.

Adult

[Relationship between pocket reduction and plaque control in initial treatment].

It has been suggested that plaque control is important in periodontal treatment. This study used O'Leary's plaque control record (PCR) to investigate the influence of plaque control in initial treatment. Thirty patients (18 men and 12 women, mean age 46.7 years) were selected for this study. The results were as follows: The mean pocket depth was reduced from 3.19 mm (at the first examination) to 2.11 mm (at re-evaluation). Mean pocket depth of 3 mm or more at the first examination was reduced from 4.09 mm to 2.43 mm. The mean number of times plaque control instruction was given to reduce the PCR 10% or less was 3.8. The quantity of pocket reduction was significantly greater in the group that underwent instructions to reduce the PCR 10% or less 4 times or less compared with the group that underwent instructions 5 times or more. The group whose mean PCR was 10% or less from the time 10% or less at the first time to re-evaluation, had significantly greater pocket reduction than the group with 20% or more. There was no correlation between pocket reduction and PCR at the first examination and bone loss scores obtained from X-ray films.

Dental Plaque

[Pocket reduction after initial treatment in relation to tooth type and site].

The purpose of this study was to compare differences in pocket reduction rate between different tooth types and sites after initial treatment. Forty-one adult periodontitis patients (mean age 40.8) whose O'Leary plaque records during initial treatment were maintained at a level of less than 10% (mean level 9.02 +/- 4.93%) were selected for this study. A total of 5983 surfaces were monitored by recording probing pocket depths (P.P.D.). The results obtained were as follows. 1. Significant probing pocket depth reduction was obtained following initial treatment (P less than 0.001). 2. Significantly improved teeth were 421/124 (p less than 0.001), 5/5 and 53/35 (p less than 0.05), and 32/23 (p less than 0.05). Deep residual P.P.D. were observed in 1/1, 6/6, 7/7, 6/6 and 7/7 (p less than 0.001), and 2/2 and 3/3 (p less than 0.05). 3. Response to treatment by tooth type was favorable in 54/45 and 431/134 and was poor in 71/17, 7/7. 4. Mandibular residual pocket depths were much deeper on proximal surfaces than on the mid-facial and lingual surfaces. Maxillary pockets on palatal surfaces were significant deeper than on facial ones. 5. Poor response to treatment was treatment was observed on the mesio-palatal surfaces (p less than 0.001), mid-palatal surfaces (p less than 0.01) of 6/6 (p less than 0.001), the distolingual surfaces of 7/7, and 7/7 (p less than 0.001), and the mesio-palatal surfaces of 1/1 (p less than 0.05). Favorable responses were observed on the disto-buccal and the id-palatal surface of 4/4 (p less than 0.05), mesio-distal buccal surfaces of 5/5 (p less than 0.05) and mesio-lingual surfaces of 4/4 (p less than 0.05). This results clearly indicate which tooth types and root surfaces must be paid careful attention to during treatment.

Humans