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Biomedical subjects

T Stricker

Publications and source records attributed to T Stricker.

15 recordsLinked to original sources
PubMed2001

Ingested pins causing perforation.

We report two children who underwent endoscopic removal of ingested foreign bodies which had perforated the stomach, one of which had migrated into the thorax.

Child↗
PubMed2000

Family history of atopy and clinical course of RSV infection in ambulatory and hospitalized infants.

Respiratory syncytial virus (RSV) infection can be severe in pediatric patients. Risk factors for severe disease include age less than 6 months, prematurity, preexisting heart or lung disease or malformations, gastroesophageal reflux, and immunodeficiency. The aim of the present study was to investigate the influence of family history of allergy on the clinical course of RSV infection in ambulatory and hospitalized infants. In a retrospective study, 172 patients younger than 12 months of age (99 inpatients and 73 outpatients) were enrolled. Information was obtained from hospital charts and from questionnaires sent to pediatricians. Inpatients had a significantly higher rate of atopy in their family history than outpatients, 62% and 29%, respectively (P < 0.001). Bronchiolitis was diagnosed more frequently in patients with an atopic burden than those without, 89% versus 74%, respectively (P < 0.02). Inpatients with an atopic family history had a significantly longer hospital stay than those without such a history, 7.4 +/- 3.7 days and 6.1 +/- 2.3 days, respectively (P < 0.04). Factors other than age that are considered a risk for severe infection with RSV (prematurity, preexisting heart or lung disease or malformation, and gastroesophageal reflux) were not confirmed in the present study. We conclude that infants with a family history of atopy are at increased risk for severe RSV infection as indicated by higher rates of hospitalization, longer hospital stay, and more frequent occurrence of bronchiolitis.

Bronchiolitis↗
PubMed2000

Helicobacter pylori infection in recurrent abdominal pain.

BACKGROUND: Helicobacter pylori is associated with chronic gastritis and peptic ulcer in adults and in children. The purpose of the present study was to analyze the association of recurrent abdominal pain and H. pylori infection in children and to evaluate the efficacy of antimicrobial treatment in patients with evidence of infection. METHODS: The clinical and histopathologic findings in children who underwent diagnostic upper endoscopy for recurrent abdominal pain were analyzed retrospectively. Patients with evidence of infection with H. pylori were treated with a combination of omeprazole, amoxicillin, and clarithromycin. Efficacy of treatment was assessed using the 13C-urea-breath test. RESULTS: H. pylori was found in histopathologic sections of 29 (40%) of 73 patients undergoing diagnostic endoscopy for recurrent abdominal pain. Five children (17%) were of Swiss ethnic origin, and 24 (83%) were non-Swiss. All the infected patients had chronic gastritis and 4 (14%) had ulcerations in the duodenum. Treatment with omeprazole, amoxicillin, and clarithromycin resulted in eradication of the infection in all and in resolution of the clinical symptoms in 15 (80%) of 19 patients who had a follow-up examination. CONCLUSIONS: The presented data suggest that gastritis induced by H. pylori may be associated with recurrent abdominal pain and that in Switzerland infections with H. pylori primarily involve persons who are non-Swiss. A combined therapy results in eradication of the bacterium and in improvement of the clinical symptoms in a significant majority of the patients.

Abdominal Pain↗
PubMed1998

Osteomyelitis and septic arthritis due to Citrobacter freundii and Haemophilus influenzae type b.

This report describes dual infection with Citrobacter freundii and Haemophilus influenzae type b causing septic arthritis and osteomyelitis of the elbow in a previously healthy 5-year-old boy. The patient was treated successfully with intravenous fosfomycin for 4 weeks. Infections with Citrobacter beyond the neonatal period are rare in paediatric patients. When Citrobacter spp. is isolated, coinfection with other bacterial pathogens should be considered.

Arthritis, Infectious↗
PubMed1991

MRI of two infants with tuberous sclerosis.

Two children (4 1/2 and 9 months of age) suffering from tuberous sclerosis were examined with MRI, using a 2.35-Tesla magnet. Both patients showed the typical brain lesions of tuberous sclerosis, namely, subependymal nodules projecting into the lateral ventricles and parenchymal hamartomas. However, in one child the examination revealed subcortical foci of low signal intensity on T2-weighted images and of high signal intensity on T1-weighted images, which could represent fat-containing hamartomas.

Brain↗
PubMed1990

Development of the human cerebellum observed with high-field-strength MR imaging.

A retrospective study of 160 pediatric subjects, aged 32-410 weeks after conception, was conducted to determine the normal developmental patterns of the human cerebellum by means of magnetic resonance (MR) imaging. On the basis of axial T2-weighted spin-echo images (repetition time, 3,000 msec; echo time, 120 msec), which provided the best contrast between gray matter and white matter, five distinct developmental stages were defined. At term, the medial lemnisci as well as the parasagittal cerebellum were myelinated. The appearance of myelin in the middle cerebellar peduncles and the basilar pons preceded that in the corpus medullare of the cerebellum. The normal age ranges for the different stages were defined with statistical analysis. These ranges are applicable to the daily routine of image interpretation. The sequence of myelination in the cerebellum observed at MR imaging correlates with the known patterns observed in pathologic studies but lags behind by an average of 6 months.

Cerebellum↗