Biomedical subjects
Publications and source records attributed to T Streicher.
The authors discuss some formations on the optic disk and close neighbourhood resembling tumours. They originate from various cellular elements in that area and are described as hamartomas. A progressive growth was recorded only in vascular hamartomas after unsuccessful therapeutic intervention, the remainder were stationary during observation periods of various lengths.
Based on 13 years observations of three generations of relatives with v. Hippel-Lindau's disease the authors focus attention on early stages of clinically detectable retinal angiomatosis. They supplement these findings by an angioma on the optic disc in one sporadic case. They consider the ophthalmological diagnosis of priority importance for the patients and risk relatives and recommend a concept of presymptomatic screening to detect other organ sites of the disease. Early detection and treatment of lesions on eyes and other organs improves the prognosis and reduces early mortality.
The authors investigated in a prospective investigation 27 patients of different age groups for 5 to 12 years with symmetrical, bilateral non-hereditary retinal drusen. The examination was focused on assessment of different types of drusen, on evaluation of the development and incidence of risk factors leading to complications and loss of central vision. The latter include the part of the spectrum of pathological manifestations in higher age groups which are included in the category of senile macular degeneration.
Juxta-foveolar telangiectasias were followed in 10 patients, when only in one patient the same clinical picture has been observed in both eyes. Decrease of the central vision was heavily deteriorated in nearly all patients, with only one exception. In some patients the glucose tolerance has been outside the normal limits, therefore authors suspect some etiologic connections between both diseases.
The authors describe their own observation of a very rare form of vitreoretinal degeneration in a young man classified as familial exudative Criswick-Schepens vitreoretinopathy. The disease was detected in the second clinical stage on the right eye and in the third clinical stage on the left eye. The transmission of the disease is autosomal dominant with incomplete penetration. In the paper special emphasis is laid on differential diagnostic problems and the possibility of treatment of this disease.
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The authors present five patients with dominant hereditary colloid bodies of the retinal centre from two family trees. Their fluoroangiographical pictures confirm the variable clinical manifestations and ophthalmological findings which because of the special colloid bodies arrangement show a resemblance to the Hutchinson-Tay, Holthouse-Batton, Doyne and Klaingutti cases, also within the framework of a single family tree. With the help of the angiogram the type and development stage can be followed, while this disease passes from functionally and ophthalmologically unimportant lesions into the final stage of atrophy and the fibrous conversion of the whole rear eye pole.
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