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Biomedical subjects

T Stoica

Publications and source records attributed to T Stoica.

32 records · Page 2Linked to original sources
PubMedDate not supplied

[Clinical and hormonal development of a case of malignant exophthalmus after hypophyseal myskiotomy].

A pituitary myskiotomy was performed in a 26-years old man with Graves' disease and progressive exophtalmus. At the onset of Graves' disease a high level of serum TSH, LATS and thyroid hormones was found. Following pituitary miskiotomy a stationary exophtalmus and other signs of Graves' disease have been recorded. The serum levels of LATS and thyroid hormones were high. The serum concentration of TSH decreased to a level undetectable even after the TRH stimulation test. It is discussed the pathogenesis of Graves' disease: its onset due to neuroendocrine disturbances (S. M. Milcu) and its evolution due to autoimmune mechanisms.

Adult↗
PubMedDate not supplied

[Colonic localization of Crohn's disease following a recurrent pseudotumor of the abdominal wall (problems of pathogenesis and therapy)].

A pseudo-tumours of the abdominal wall is described, in the left hypochondrum and the left flank, that, recidivating after 5 years, invaded the splenic angle of the colon. The common histological characteristics were very clear and strongly suggested the presence of Crohn disease. The cellular elements found at the first intervention performed for the extirpation of the tumour in the abdominal wall, as well as at reintervention--consisting in the block resection of the recidivating tumour and of the segment of the colon involved (segmental colectomy)--represented by abundant plasmocytic infiltrates suggest the presence of an immune process. The problem raised is the possibility that the Crohn disease could be incriminated in both instances, since the immunological disturbances can be considered as clearly manifest.

Abdominal Muscles↗
PubMedDate not supplied

Progressive "empty sella" syndrome, gonadotropins deficiency and congenital aqueductal stenosis. Case report.

A 23-year old woman had both the empty sella syndrome (ESS) and congenital stenosis of the aqueduct of Sylvius, diagnosed by fractionated pneumencephalography. A progressive increase of the pituitary fossa followed a brisk intracranial hypertension. Dynamic pituitary function tests show a secondary gonadotropin deficiency. The role of intracranial pressure in the pathogenesis of "empty sella" syndrome, as well as the necessity to investigate by pneumencephalography all the patients with progressive enlargement of sella turcica and secondary pituitary deficiency are suggested.

Adrenal Cortex Hormones↗
PubMedDate not supplied

Additional antitumoral effects of bromocriptine and radiotherapy in patients with prolactinomas or acromegaly.

Thirteen patients with prolactin-secreting and/or growth hormone secreting pituitary tumours have been treated with bromocriptine in doses of about 10 mg/day for several months. Nine of these patients were previously submitted to external or interstitial radiotherapy and one case to pituitary microsurgery. Serum prolactin concentration in patients with prolactinomas was still very high within one year after pituitary irradiation or operation, i.e. 5,125.6 +/- 974 mU/l (mean +/- SEM). It has been reduced to normal level only during bromocriptine therapy, i.e. to 329.1 +/- 88mU/l (p less than 0.001), and increased thereafter, but remained to a significantly lower concentration than before bromocriptine treatment, i.e. 2,709.0 +/- 553 mU/l (p less than 0.05). Serial pneumonecephalotomography has demonstrated the reduction of tumour size afrer bromcriptine therapy to two prolactinomas with suprasellar extension. In patients with acromegaly the effects of bromocriptine were less evident. The antitumoral effects of bromocriptine on prolactin-secreting adenomas is independent and additional to the effects of pituitary radiotherapy or microsurgery, and has therapeuticical implications.

Acromegaly↗
PubMedDate not supplied

[Hepatic hydatid cyst in minimally invasive surgery].

The hydatid cyst, especially the hepatic one has come to be considered, for some years ago, in the Mediterranean and Black Sea's countries. The distribution area of this disease has a common feature beyond the geographical area once the agricultural-economic characteristics. A disease with a therapeutic visa, especially a digestive one with highly recognized invasion can be treated using laparoscopic treatment for most of the cases, excepting cysto-digestive sutures as therapeutical solutions. That is why we inform you about some of our results, the therapeutical adapted solutions and the issued complications.

Echinococcosis, Hepatic↗