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Biomedical subjects

T Stadnik

Publications and source records attributed to T Stadnik.

At least 37 records · Page 2Linked to original sources

Easy preoperative planning of deeply located brain lesions using external skin reference and 3-dimensional surface MRI.

Open skull surgery of deeply located intracerebral lesions requires precise determination of the treatment area in 3-dimensional (3-D) space. 3-D MRI can give important additional information in presurgical determination of the surgical approach to the target, taking into account highly functional brain areas and important vascular structures. The day before surgery, a grid composed of 9 tubings intersecting at 90 degrees at 1 cm intervals and filled with a CuSO4 solution is firmly attached to the skin of the patient's head in the presumed region of the craniotomy. A 3-D turbo-FLASH sequence is then performed in the sagittal plane after intravenous Gd-DOTA injection on a 1T Magneton. 3-D surface reconstruction of the cortical gyri and sulci is performed. Once the gyri are identified, the 3-D program is then implemented in order to perform a color display of the cortical veins and of the tumor boundaries. The surgical access is then chosen by the surgeon, taking into account highly functional areas. Finally, the boundaries of the tumor are projected on the cortex reconstruction and on the external reference placed on the skin. The entry place for surgery as well as the size of craniotomy are drawn on the skin and the tubed grid is removed. The accuracy of this method tested in 9 patients with deeply located brain tumors or arteriovenous malformations was very satisfactory.(ABSTRACT TRUNCATED AT 250 WORDS)

Brain↗

Contrast behavior between microadenoma and normal pituitary gland after gadolinium injection as a function of time at 1.5 T.

The behavior of contrast enhancement between a microadenoma and the normal pituitary gland after gadolinium injection was evaluated in 12 operatively confirmed cases using a repetitive sequence of four coronal T1-weighted spin echo series (T1 SE) (continuous acquisition, TR = 400 ms), followed by conventional coronal T1 SE (TR = 600 ms) and a three-dimensional fast low-angle shot sequence. The first and second acquisitions were useful with respect to delayed scans only in 3 cases (25%). Nevertheless, in these cases confident diagnosis could also be made on pre-contrast studies, which diminishes the real advantage of this finding. For a 1.5 T MRI unit we advocate starting with coronal T1 SE 30 s after a rapid injection of gadolinium.

Adenoma↗

Spinal arachnoiditis mimicking a spinal cord tumor: a case report and review of the literature.

We report on an unusual case of idiopathic arachnoiditis mimicking a spinal cord tumor in a 50-year-old man with progressive paraparesis. The medical imaging work-up showed an enlarged terminal cone with adjacent cysts. Although there was no enhancement of the terminal cone or the surrounding structures, the diagnosis of spinal cord tumor was maintained and surgery was carried out. Exploration of the cauda equina and the tissue surrounding the terminal cone did not reveal a tumor. The patient improved dramatically after surgery but the symptoms recurred 1 year later. We review arachnoiditis, its pathology, and its treatment with special attention drawn to the primary form of spinal arachnoiditis.

Arachnoiditis↗

Treatment of macroprolactinomas with the long-acting and repeatable form of bromocriptine: a report on 29 cases.

Twenty-nine patients with macroprolactinomas were treated by monthly intramuscular injections of the long-acting and repeatable form of bromocriptine (Parlodel-LAR) in doses ranging from 50-150 mg. They were divided into two groups: group I consisted of 22 patients who received Parlodel LAR before transsphenoidal adenomectomy; group II was composed of 7 patients with earlier neurosurgery and of 2 patients from group I not cured by transsphenoidal adenomectomy. Duration of therapy varied from 1-12 months, and a total of 104 injections was given. At nadir day, serum PRL levels were situated between less than 1% and 43% of pretreatment values. At day 28 after the first injection, serum PRL levels varied between less than 1% to 139% of initial values. No difference could be detected between the two groups regarding the percent of PRL inhibition. Long-term treatment with Parlodel-LAR resulted in a sustained inhibition of PRL secretion, except for 1 case. Resumption of menstrual cycles occurred in 4 out of 15 women and correction of hypogonadism in 4 out of 14 men. Amelioration of disturbed visual fields was recorded in 3 out of 8 patients. Diminution of the adenoma volume was radiologically documented in 14 out of 22 cases. Only few and mild side effects were recorded. One patient with partial adrenal deficiency suffered from a syncope, but this was prevented by hydrocortisone supplementation during the subsequent Parlodel-LAR administration. In conclusion, Parlodel-LAR proved effective in the treatment of macroprolactinomas, achieving rapid inhibition of PRL secretion, and in some patients amelioration of hypopituitarism, reduction in tumor size, and improvement in visual fields, and caused no serious side effects. It is a valuable preparation to surgery and can also be used in long-term medical therapy.

Adult↗

CT and MR findings in ruptured dermoid cyst in the right parasellar cistern: report of a case.

A case of ruptured dermoid cyst in the right parasellar cistern imaged by MRI and CT is reported. The disseminated lipid droplets were found scattered throughout the subarachnoid spaces including the prepontine cisterns, in front of the right petrous apex as well as bilaterally in the frontal horns. The density of the lipid droplets was comprised between -80 and -100 HU. The lesions were hyperintense on T1-weighted images and hypointense on T2-weighted images.

Adult↗

Solitary dorsal intramedullary schwannoma. Case report.

A case of solitary dorsal intramedullary schwannoma diagnosed by magnetic resonance imaging and treated surgically is reported. The authors review the previously published cases. The possible etiology of the tumor as well as some difficulties encountered in the diagnostic procedure and treatment are discussed.

Female↗

Pituitary microadenomas: diagnosis with two-and three-dimensional MR imaging at 1.5 T before and after injection of gadolinium.

The usefulness of different magnetic resonance (MR) imaging sequences (coronal and sagittal spin-echo [SE] and three-dimensional fast low-angle shot [3D FLASH]) in the detection of pituitary microadenomas before and after gadolinium injection was prospectively evaluated in 28 patients with surgical confirmation. When evaluated separately, the most useful sequences in the detection of these microadenomas were coronal pregadolinium T1-weighted SE, coronal pregadolinium 3D FLASH, coronal postgadolinium T1-weighted SE, and coronal postgadolinium 3D FLASH. The combination of pre- and postgadolinium T1-weighted sequences with pre-and postgadolinium 3D FLASH sequences produced the highest number of true-positive findings (90%) and the lowest number of false-positive findings (5%). When a 1.5-T imaging unit with a high signal-to-noise ratio allowing useful three-dimensional acquisition is used, the authors advocate a coronal T1-weighted SE sequence, followed (if necessary) by a coronal 3D FLASH sequence, both without injection of gadolinium, in the diagnosis of pituitary microadenomas. When no confident diagnosis is reached, the same sequences should be performed after the injection of gadolinium. The sagittal pre- and postgadolinium T1-weighted SE and long-TR SE sequences are useful only in specific cases.

Adenoma↗

Diffusion-weighted MR imaging of an acute venous stroke: case report.

A patient with a superior sagittal sinus thrombosis had progressively worsening symptoms and signs that resolved after IV heparin therapy. MR imaging revealed abnormalities in diffusion, similar to those seen with acute arterial stroke. Abnormalities shown on a T2-weighted fast spin-echo and fluid-attenuated inversion recovery images resolved completely. The findings in this report contradict those from previous reports that suggest diffusion-weighted imaging with quantitative apparent diffusion coefficients may be used in selecting patients for dural venous sinus thrombolysis.

Adult↗

Health screening with CT: prospective assessment of radiation dose and associated detriment.

The use of computed tomography (CT) for screening of targeted diseases is gaining much interest in the international medical community. An important aspect in the justification of screening with such a high dose examination is the radiation dose to the patient. The objective of this study was to perform a prospective assessment of the radiation dose and associated risk for deleterious effects from a CT screening programme. The excess lifetime risk of fatal cancer for various screening strategies was quantified by estimating the effective dose and by using age dependent mortality risk factors. The accrued data shows that the excess mortality risk due to screening with CT could be substantial. It ranges from 0.01% up to a few percent, strongly depending on the type and method of screening. Consequently, radiation dose and associate risk should be included as fundamental parameters for outlining and deciding a screening approach with CT. Recent technical developments, such as tube current modulation, are promising tools for dose reduction within the constraint of desired image quality.

Abdomen↗

Non-traumatic subdural hygroma.

Subdural hygroma consists of a cerebrospinal fluid-like subdural fluid collection with a low oncotic pressure in comparison with venous blood. Its etiology and pathophysiology, which may be different from other subdural fluid collections, are reviewed. We report the clinical history of a 80-year-old woman with a bilateral frontal subdural hygroma. Serial CT-scanning demonstrated a rapid increase in volume after two years of slow evolution. In our patient dehydration may have been the triggering factor. The course of non-traumatic subdural hygroma is not well known. This report illustrates that subdural hygroma can have a dramatic evolution and that therapeutic decisions in these patients should be based on repeated CT-scans.

Aged↗

Spinal osteomyelitis: an unusual complication in aortic graft surgery.

The case history of a patient with vertebral osteomyelitis due to a contiguous paraprosthetic aortic abscess is reported. This unusual complication may be associated with the indolent nature of paraprosthetic aortic infections. The diagnostic as well as therapeutic value of computerised tomography in this condition is emphasized.

Abscess↗