[Use of talampicillin for the diseases of the mouth].
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Biomedical subjects
Publications and source records attributed to T Soda.
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A case of membranous glomerulonephritis with initial proliferative changes accompanied by nephrotic syndrome was followed up for seven years. With three serially obtained renal biopsy tissues, the regression of the glomerular membranous alterations was confirmed after the remission of nephrotic syndrome. The diagnosis of lupus nephritis was not conclusive but was suggestive. The resolution of the basement membrane seemed to start structurally at the outer, epithelial surface of the membrane with the formation of basement membrane material. The "microtubular structures" in the glomerular endothelial cytoplasm were continuously observed in three renal tissues obtained serially for five years, regardless of the clinical remission and of glomerularstructural resolution.
The content of IgG, IgA, IgM, transferrin, haptoglobin, alpha2 macroglobulin, alpha1 acid glycoprotein, alpha1 antitrypsin, beta1C/1A globulin and beta1E globulin in the sera of 172 female rheumatoid patients and 132 female non-rheumatoid subjects was measured by the single radial immunodiffusion method. Rheumatoid patients were classified into 3 groups according to their stage and class. Canonical discriminant analysis revealed that the alpha1 acid glycoprotein and beta1C/1A globulin was of assistance in differentiating the rheumatoid and non-rheumatoid groups. There is no significant difference in serum protein levels between rheumatoid factor positive and negative groups, whereas IgA and beta1E globulin levels exhibited certain differences between these two groups. Among the results of other clinical tests, the correlation observed between ESR and serum protein levels in rheumatoid arthritis should be mentioned.
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Based on the correlation of LM, EM and IF findings of kidney biopsy tissues with the clinical and laboratory findings as well as renal function, classification of primary GN is proposed with special reference to the smouldering and progressive forms of chronic GN. The two forms of chronic GN should be differentiated because their prognoses are different.
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