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Biomedical subjects

T Simonart

Publications and source records attributed to T Simonart.

81 records · Page 5Linked to original sources
PubMed1997

Overlap of sarcoidosis and rosacea.

Numerous descriptions have been applied to rosacea-like eruptions of the face, some of them remaining of questionable nosologic significance. A case of rosacea-like syndrome with lacrimal, ocular and salivary involvement is described. The differential diagnosis and therapeutic response of this unusual association are discussed.

Adult↗
PubMed1996

A unique clonal chromosome 2 deletion in endomyometriosis.

The cytogenetic analysis of a short-term culture from a so-called endomyometriosis revealed a unique clonal del(2)(p21). The embryologic origin of this uterine-like mass is controversial. The finding of a clonal chromosome aberration favors the proliferation hypothesis and suggests that endomyometriosis is a true neoplasm and that a somatic mutation might be involved in the etiology of this lesion.

Chromosome Banding↗
PubMed1994

Particularities of urticaria seen in the emergency department.

Acute urticaria represents the most commonly observed skin disorder (35%) presenting in an emergency department. We retrospectively analysed the records of 676 patients admitted for acute urticaria in order to know the particularities and the main aetiologies. The mean age was 28; females being more affected than males. Aetiologies varied according to age; drugs were involved in 50% of patients more than 50-years old and in only 19% of children less than 10 years old. Whilst causes are rarely known in the chronic forms, almost 60% of the acute cases were due to drugs or food. Amongst the former, antibiotics and NSAI were the most frequently met.

Adolescent↗
PubMed1993

[Streptococcus beta hemolytic necrotizing fasciitis. 5 cases in the Brussels area].

In the Brussels area five cases of necrotizing fasciitis occurred during the past two years in patients devoid of any pathology likely to lower the immune defence mechanisms. Alcoholism and the use of non-steroidal anti-inflammatory drugs seem to act as contributory factors. Necrotizing fasciitis develops alone or as complication of a pre-existent dermo-hypodermic infection. A massive use of antibiotics and a wide surgical slitting up failed to prevent a fatal issue in all five patients. Extremely early massive surgery remains vital in this disease.

Adult↗
PubMed1993

[Epidemiology and etiopathogeny of necrotizing fasciitis and streptococcal shock syndrome].

A significant increase in the frequency of necrotizing fasciitis caused by streptococci of group A has recently been noted. The disease usually appears in individuals without obvious risk factors. The initial lesion is often quite ordinary, and the evolution towards a toxic shock very swift. This evolution can be summarized as follows: 1) localized infection; 2) bacteraemia with circulating toxins and soft tissue necrosis; 3) production of cytokines by the immune cells of the host, leading to a rapidly irreversible toxic shock Serotypes 1, 3, 12 and 28 of group A streptococcus are usually involved. The virulence of some serotypes might be explained by the acquisition of a toxic gene. The sensitivity of the host is linked to the genetic expression of the V. beta. elements on the surface of lymphocytes. Antibiotics cannot save the patient when necrotizing fasciitis is installed. Surgery must be massive and performed early.

Adult↗