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Biomedical subjects

T Shiramizu

Publications and source records attributed to T Shiramizu.

26 records · Page 2Linked to original sources
PubMed1982

Complication of renal neoplasms with cystic disease: an indication for nephrectomy in potential transplant recipients.

Thirty-five (1.1%) out of a total of 3,133 autopsied cases of renal tumors were complicated by renal malignant tumors and cystic renal disease. They accounted for 1.4% of 2,417 cases of renal malignant tumors and for 4.7% of 751 cases of cystic renal disease. Among the 35 complicated cases, 10 cases or 28.6% were free of metastasis. The incidence of complicated cases and those without metastasis aged over 60 years or over was 12.2% and 29.2% respectively, while the 10-59 year-old age group displayed a lower incidence of 3.6% and the same incidence of 27.3% respectively. In 26 out of 35 cases the malignant tumors was renal adenocarcinoma with no evidence of metastasis in nine cases (34.6%). Although it is unknown whether cystic renal disease undergoes malignant changes, not all of the patients undergoing chronic hemodialysis should be indicated for nephrectomies since such patients with renal malignancies are mostly elderly and are frequently free from metastases.

Adolescent↗
PubMed1982

Experience of 26 acute renal failure cases.

Data from 26 patients in acute renal failure biopsy have been analysed to define the highest risk factors and to evaluated the reversibility of renal functions. The overall mortality rate was 38 per cent. The mortality (69%) in postsurgical and traumatic cases was significantly higher than that (8%) in cases of obstetrical and medical origin. Survivors and nonsurvivors did not differ in time of initiation of dialysis. There was an increased incidence of gastrointestinal hemorrhage in those who died. A serious underlying disease, infection and gastrointestinal hemorrhage were mainly responsible for deaths. Five of the 16 survivors were left with renal failure and two of them required chronic hemodialysis.

Acute Kidney Injury↗
PubMed1982

Renal function after nephrectomy in renal donors.

Six months to 5 years after nephrectomy in renal donors, creatinine clearances and PSP tests of 34 cases had recovered to 81.8% and 68.2% respectively of prenephrectomy performance. Blood urea nitrogen, creatinine and uric acid levels had increased to 24.9%, 36.7% and 24.3% respectively of prenephrectomy values. There was compensatory hypertrophy of the remaining kidney. The mean increase in size of the remaining kidney was 12.0% x 17.8%. There were early complications in 11 (32%) of the donors, in the form of pneumothorax in six cases, wound infection in two cases, hepatitis in two cases and urinary tract infection in one case. There was one late complication of neuralgic pain in the scar region.

Adult↗
PubMed1981

Acute irreversible rejection after withdrawal of azathioprine in renal allograft recipients.

Azathioprine was withdrawn from five recipients after renal transplantation because of hepatic damage. In three out of five cases, clinical courses were uneventful for more than 1 year after withdrawal (Group A). In the other two cases, rejection episodes occurred 3 and 5 months after withdrawal (Group B). Differences in histocompatibility, the interval between the operation and withdrawal, and the maintenance dosis of prednisolone were not practically striking in either group, but rejection episodes occurred early in group B. We evaluated the results and considered the mechanisms of tolerance after withdrawal of azathioprine because of hepatic damage in renal allograft recipients.

Adult↗
PubMed1981

Clinical considerations of renal allograft pathology.

Eleven out of 31 cases of living renal allografts lost their graft functions. Causes of graft loss were acute rejection in eight cases chronic rejection in one, graft rupture in one, and death due to meningitis with good graft function in one case. Five renal allografts and two biopsy specimens obtained after acute irreversible rejection and one renal allograft due to acute tubular necrosis an rupture were reviewed. We evaluated the correlation between these findings and the irreversibility of renal graft functions. All removed allografts and biopsies demonstrated interstitial edema and cell infiltration. Vascular pathology due to acute irreversible rejection revealed a high level of severity with fibrinoid necrosis and luminal obliteration. These findings suggested that graftectomy and cessation of immunosuppressants were indicated.

Graft Rejection↗
PubMed1981

Acceleration of lipid peroxidation in human paraquat poisoning.

A 20-year-old man ingested approximately 15 to 20 mL of a 24% solution of paraquat. Acute renal and liver failure developed. The patient began undergoing hemodialysis and receiving vitamin E, but he died of pulmonary fibrosis the 27th day after the ingestion. During a two-week period of observation, evidence of lipid peroxidation in his serum was noted by determining malondialdehyde levels. Guinea pigs exposed to paraquat showed similar patterns of malondialdehyde presence in plasma. These results indicate that increased serum or plasma levels of lipid peroxide occurring in paraquat poisoning might reflect production of highly reactive oxygen free radicals and that, possibly, levels of lipid peroxides could serve as indicators of the efficacy of therapy directed toward scavenging free radicals.

Adult↗
PubMed1981

Clinical report on hemodialysis in the Department of Transplantation, Tokai University School of Medicine.

The Department of Transplantation, Tokai University School of Medicine was opened in April 1975. There were 286 patients treated by regular hemodialysis and 30 transplantation patients in the five year period from 1975 to 1980 in our Department. The total number of patients treated by regular hemodialysis alive in June 30, 1980 was 244 (85.3%). In the regular hemodialysis group, the peak age was 30-39 years. The youngest patient was nine years old and the oldest was 85 years old. The male : female ratio of chronic renal failure patients treated by regular hemodialysis was 67 : 33%. The actual five-year survival rate for patients treated by regular hemodialysis was 82%. The most prominent cause of chronic renal failure was glomerulonephritis (86.6%). The major cause of death in regular dialysis patients was gastrointestinal hemorrhage (22.6%). We had 81 cases of acute renal failure and 20 (24.7%) of these patients were treated by hemodialysis. Six cases with no acute or chronic renal failure were treated by hemodialysis.

Acute Kidney Injury↗