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Biomedical subjects

T Shimada

Publications and source records attributed to T Shimada.

At least 1,063 records · Page 59Linked to original sources

Chromosome mutations and pH disturbances.

Chromosomal anomalies, namely hypodiploidies, hyperdiploidies, and endoreduplications, developed in nearly 25% of metaphase plates of replicating human lymphocytes exposed in vitro to either acid (6.5 to 6.9) or alkaline (8.4 to 8.8) pH equilibriums. The G group was most susceptible to aneuploid formation. Mammalian mutations may develop as the result of a pH disturbance during cleavage of the fertilized zygote.

Aneuploidy↗

Scanning electron microscopy of epididymal ducts in the Japanese monkey (Macacus fuscatus) with special reference to the architectural analysis of stereocilia.

The luminal surface of the initial segment of the epididymal duct in the Japanese monkey was observed under a field emission type scanning electron microscope. The long, slender stereocilia projecting from the apical surface of the columnar cells were found to be closely arranged in a funnel-like form opening to the lumen. The funnels formed by stereocilia were also confirmed by observation of thin sections cut from the same specimen used for scanning electron microscopy and their bottom was located in the center of the vertex of each columnar cell.

Animals↗

Ultrastructural changes of the hypothalamo-hypophysial neurosecretory system in the magnesium deficient rats.

A magnesium deficient diet caused transient but marked degenerative changes in the rat hypothalamo-hypophysial neurosecretory system which strongly resembled in many ultrastructural respects those induced by a prolonged administration of aldosterone as previously reported by us. The possible mechanism for this selective alteration in the neurosecretory neurons has been briefly discussed with regard to aldosterone secretion.

Acid Phosphatase↗