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Biomedical subjects

T Shigemitsu

Publications and source records attributed to T Shigemitsu.

11 recordsLinked to original sources
PubMed1991

Ultrastructural study of adsorbed protein on extracted intraocular lenses.

A comparative study was made of 33 explanted intraocular lenses (IOL) by stereomicroscope, light microscope, phase-contrast microscope, scanning electron microscope and transmission electron microscope. The materials of the extracted lenses were polymethylmethacrylate (PMMA), silicone, polyhydroxyethylmethacrylate (PHEMA) and coated PMMA. The implanted period varied between 3 days and 88 months. An ultrathin membrane-like structure composed of fine, granular material, 0.01 to 0.08 microns thick, that covered the entire explanted IOL surface was observed regardless of the implant period and kind of IOL. The structure was determined to be a layer of adsorbed protein since it showed a positive reaction to protein stainings such as Ponceau 3R, nigrosine or ruthenium red. No membranous structure or cellular deposit could be seen on the surface of the unused PMMA IOL which served as a control.

Adsorption↗
PubMed1989

[Fibrin deposits on the surface modified PMMA IOLs].

Fibrin reaction and fibrin deposits on the surface of intraocular lens (IOL) after implantation were studied experimentally in vitro and in vivo, using various surface-modified PMMA IOLs. PEO-coated PMMA IOLs and heparinized PEO-coated PMMA IOLs prevented deposition of fibrin. The results suggested these IOLs would be useful to prevent accumulation of fibrin deposits.

Animals↗
PubMed1977

Fundamental aspects of antimony thin film electrodes for pH measurement.

This report concerns the investigation of the sensitivity, temperature dependence, accuracy, and the standard electrode potential EO of an antimony thin film pH electrode which was prepared with electron beam evaporation techniques. The air-formed oxide film on antimony thin film electrodes has been proved by both the cathodic reduction method and electron spectroscopy for chemical analysis (ESCA). The antimony thin film electrode responded rapidly to pH changes and its sensitivity was slightly changed depending on the buffer composition. The accuracy of this electrode was compared with that of the glass electrode. Temperature had some influence on the function of this electrode. The standard electrode potential of this electrode was discussed together with that of other forms of antimony electrodes. The structure and thickness of the surface oxide on antimony thin film electrodes was confirmed by cathodic reduction and ESCA. It was clear that the surface oxide governs the electrode reactions. Possible applications of the antimony thin film electrode are discussed stating some limitations in the use.

Antimony↗