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Biomedical subjects

T Sakae

Publications and source records attributed to T Sakae.

At least 55 records · Page 3Linked to original sources
PubMed1987

Brushite in fibrous dysplasia of the jaw bone.

Crystals associated with the maxillary bone in a case of fibrous dysplasia were investigated histopathologically, crystallo-graphically and by infrared absorption spectroscopy. Light microscopically, the crystals showed a transparent and plate-like appearance, and were revealed to be piled, incomplete monoclinic structures up to 250 micron in size by scanning electron microscopy. These crystals were identified as brushite, dicalcium phosphate dihydrate CaHPO4.2H2O, by X-ray microdiffraction and infrared absorption spectroscopic analysis. From consideration of the equilibrium of brushite, it was assumed in this case that inflammation had occurred initially and that the tissue fluid conditions at the site of the lesion had deviated from normal, eventually resulting in the deposition of brushite crystals on the bone apatite. From a crystallographic view point, the mode of occurrence of brushite suggested that the bone at the lesion site would not recover through normal healing.

Adolescent↗
PubMed1987

Crystals and calcification patterns in two lymph node calcifications.

Two calcified lymph nodes from the submandibular and neck regions, were studied by micro-radiography, X-ray micro-diffraction and X-ray micro-analysis. The submandibular specimen showed a conglomerate texture of small blocks which seemed to reflect the lobular structure of the lymph node. The degree of calcification of these blocks varied from one location to another. The neck specimen was composed of several islets surrounded by soft tissues. The main islet showed a central X-ray translucent region and outer calcified layers which could be subdivided into 2 types; those with spherulitic calcification and those with smooth calcification. In the submandibular specimen, well crystallized apatite was found, sometimes together with a minor amount of whitlockite. In the neck specimen, isolated and well-crystallized whitlockite was found most frequently in the regions of spherulitic calcification. The occurrence of whitlockite in both specimens was attributed to the sporadic distribution of magnesium, as revealed by X-ray micro-analysis.

Calcinosis↗
PubMed1986

Phlebolithiasis associated with intramuscular hemangioma. X-ray diffractometric, X-ray microanalytical and scanning electron microscopic investigations.

Phlebolithiasis associated with intramuscular hemangioma is relatively rare. Combined crystallographic, microanalytical and morphological studies have not been done before. We investigated a case of phlebolithiasis by scanning electron microscopy, X-ray microdiffractometry and energy-dispersive X-ray microanalysis. The calculus revealed a lamellar structure with irregular distribution of radipaque and radiolucent portions. The radiopaque portions contained apatite which could be demonstrated in prismlike as well as globular granular structures. In contrast to other authors, brushite was not detected by us. The radiolucent protions adjacent to the stone surface contained sulfur and showed undefined diffraction peaks supposing the presence of organic crystals. The possible milieu factors govering calculus formation are discussed.

Adult↗