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Biomedical subjects

T Sándor

Publications and source records attributed to T Sándor.

At least 19 recordsLinked to original sources
PubMed1997

[Striking increase in mortality from venous diseases in Hungary].

The statistical data of the World Health Organisation were studied from 1970 to 1990 to evaluate changes in mortality caused by venous diseases in 9 European countries and in the USA. The data were analysed in process and mortality rates in Hungary and in other countries were compared. In 1970 data based on general population of Hungary indicated medium incidence of mortality due to vein pathology (10.8/100,000) compared to the economically more developed countries. Unfortunately by 1990 mortality due to venous diseases almost had doubled (19.8/100,000). During this 20 years period mortality rates caused by venous diseases gradually decreased in the USA and in most European countries, e.g. by 80% in Austria and by 70% in Finland. Even the relatively high mortality caused by venous diseases in Switzerland (10/100,000) comprises only 50% of that demonstrated in Hungary. While the significance of modern thromboprophylaxis was recognised in the Western European countries and the USA in the early seventies, a delay of the introduction of prophylaxis with low-dose heparin was observed in Hungary. Socio-economic and nutritional causes could have been contributed to the high mortality rates caused by venous diseases as well. Further epidemiologic investigations focusing on venous morbidity factors and wide scale application of organised preventive programme are suggested.

Adolescent↗
PubMed1996

Age-related changes in intracranial compartment volumes in normal adults assessed by magnetic resonance imaging.

Magnetic resonance (MR) image-based computerized segmentation was used to measure various intracranial compartments in 49 normal volunteers ranging in age from 24 to 80 years to determine age-related changes in brain, ventricular, and extraventricular cerebrospinal fluid (CSF) volumes. The total intracranial volume (sum of brain, ventricular, and extraventricular CSF) averaged 1469 +/- 102 cm3 in men and 1289 +/- 111 cm3 in women. The difference was attributable primarily to brain volume, which accounted for 88.6% of the respective intracranial volumes in both sexes, but was significantly larger in men (1302 +/- 112 cm3) than in women (1143 +/- 105 cm3). In both, the cranial CSF volume averaged 11.4%. Total intracranial volume did not change with age, although the normalized brain volume of both men and women began to decrease after the age of 40 years. This decrease was best reflected by expansion of the extraventricular CSF volume which, after the age of 50 years, was more marked in men than in women. The volume of the cranial CSF, as determined by MR image-based computerized segmentation, is considerably larger than traditionally accepted and resides mostly extraventricularly. Expansion of CSF volume with age provides a good index of brain shrinkage although evolving changes and growth of the head with age tend to confound the results.

Adult↗
PubMed1988

[Radioisotope studies of the spontaneous course of postoperative deep venous thrombosis].

Radiofibrinogen tests were applied to 88 surgical and urological patients with postoperative thrombosis of deep veins to establish point and time of thrombus origin and courses taken by thrombi. Most of the thrombi thus recorded had originated from venous bulges of the calf, the soleus sinus. These accounted for 83 per cent of all thrombi detected. Progress was in all cases in proximal direction, towards the popliteofemoral veins. The intraoperative phase was found to be the most dangerous juncture for the development of thrombi, with 36 per cent of all thrombi emerging on the day of surgery and another 22 per cent on the first and second postoperative days. Prophylaxis against thrombosis, therefore, should be initiated prior to surgical intervention in any case. Bilateral thrombosis was recorded from 22 cases. Sixty-one per cent of all thromboses were localised on the left side, and 81 per cent of all postoperative thromboses were clinically latent. There were six non-lethal outbreaks of pulmonary embolism and one lethal case. While the majority of calf vein thromboses was relatively harmless, the risk of pulmonary embolism increased considerably, as thrombi emerged at the level of the popliteal vein. Radioisotope investigation can be used to identify deep vein thrombosis and to figure out those patients in whom pulmonary embolism or chronic venous insufficiency may be expected to develop.

Fibrinogen↗
PubMed1986

Prevention of postoperative thromboembolisms in general surgery by the combination of heparin and dihydroergotamine.

The effect and the degree of safety of administering a fixed combination of 5000 IU of heparin + 0.5 mg dihydroergotamine (HDHE s.c. per every 12 hours) as opposed to 5000 IU of heparin (LDH s.c. every 8 hours) was assessed in a prospective randomized study on 86 patients having undergone major abdominal operation. Postoperatively a deep vein thrombosis was detected by the radiofibrinogen test in 10% of the 40 patients of the HDHE group and in 13% of 46 of the LDH group. Four patients died. At autopsy neither fatal nor a contributing pulmonary embolism was found. 'Non-lethal' pulmonary embolism diagnosed by lung perfusion scintigraphy and by chest X-rays, developed in 2 patients treated with LDH and in one treated with HDHE. Two-thirds of the dose of heparin were identically effective in prevention of venous thromboembolisms than the whole dose if heparin was combined with DHE. The decrease of the heparin dose significantly reduced the number of wound haematomas and of suffusion due to injection.

Adult↗
PubMed1976

[Acute traumatic infratentorial subdural hematoma].

The case of an injured man, aged 54, is reported. On the basis of the neurological symptoms, without neuro-radiological contrast examinations, in presence of negative skull osteogram, on the day of the injury suboccipital craniectomy and removal of the subdural haematoma have been performed. The diagnostical difficulties of the occipital injury are pointed out, since both the occipital and infratentorial regions are "silent" regions for the carotis-angiography. In the case of subdural haematoma the suboccipital decompression performed in due time may be exactly as much successful as the supratentorial decompression.

Accidents, Traffic↗
PubMed1976

Familial occurrence of giant cell hepatitis in infancy.

The repeated occurrence within one family or giant cell hepatitis terminating in death is reported. The familial form of giant cell hepatitis has a poorer prognosis than that occuring sporadically. In the first case, reported earlier, primary liver cancer developed within a short time. In the second case, reported here, the progression of the course of the disease which terminated in cirrhosis was followed in a series of histological examinatons made at five different points of time. Electronmicroscopic examination were also conducted.

Female↗
PubMed1975

[Primary humero-radial arthrodesis].

The surgical treatment of a severe injury in the cubital region of a bus-driver, aged 47, is reported. Because of the extended contamination and the splintered fracture radical wound excision - involving also the chondral surfaces - has been performed and hereupon humero-radial arthrodesis was carried out. The skin defect has been successfully treated secondarily by insert of a flap. After uneventful recovery the patient could resume his work 6 months after the injury again.

Accidents, Traffic↗
PubMed1975

[Injuries of the cervical spine].

In connection with 44 patients, who suffered injuries of the cervical spine, the types of the fracture and dislocation of the cervical spine are discussed. The injuries of the cervical spine--with or without injury of the spinal marrow--signify hard tast in respect of therapy. The conservative (extension) treatment of surgical intervention are even nowadays much debated themes in the neurosurgery. The introduction of Crutchfield tongs was a definite advance in the latter years. With this treatment method the restitution of the form, continuity and stability of the cervical spine is possible. In the opinion of the authors, surgical intervention (laminectomy) is necessary only in the case of progressive symptoms of compression of the cervival marrow (liquorstop). The survival of the patients depends often on the quick and proper treatment. The prevention of complications and the quick elimination are of great importance. Safeguarding of the physical and psychical conditions of the patients is the essential requirement of their rehabilitation after injuries of the cervical spine.

Accidents, Occupational↗