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Biomedical subjects

T S Parrott

Publications and source records attributed to T S Parrott.

At least 37 records · Page 2Linked to original sources

The expanded role of transureteroureterostomy in pediatric urology.

Transureteroureterostomy was used in 31 patients as a component in urinary undiversions, salvage procedures for failed reimplants/reconstructions and diversions with a sigmoid antirefluxing conduit or end cutaneous ureterostomy, as well as an adjunct to reimplantation procedures complicated by an abnormal bladder that precluded reimplantation of more than 1 ureter. Reconstruction in 29 patients involved procedures that changed the drainage of the recipient ureters for various reasons, including obstruction, reflux, undiversion and diversion. A neurogenic bladder was present in 26 patients and an additional 4 patients had a significant bladder pathological condition. Both ureters were dilated in 17 patients, while 1 was dilated in another 6. This series illustrates the versatility and confirms the success of transureteroureterostomy in high risk, complicated reconstructive urological procedures in children.

Adolescent↗

Chylous ascites following retroperitoneal lymphadenectomy for granulosa cell tumor of the testis.

We report on an infant with chylous ascites following retroperitoneal lymphadenectomy for granulosa cell tumor of the testis. Granulosa cell tumor of the testis is an extremely rare lesion, with only 8 cases reported previously, including 1 in an infant. Chylous ascites is a rare problem in children and it has been reported in only 92 cases. The options for management of this difficult problem are discussed.

Chylous Ascites↗

Urologic implications of anorectal malformations.

The urologist has assumed a major role in the management of the child with imperforate anus. Fistulas from the rectum to the urinary tract, as well as associated genitourinary anomalies such as vesicoureteral reflux, make the urologist an important member of the team managing imperforate anus. Special spheres of urologic interest occur immediately (when accurate imaging is important), during the first year (when urinary tract infections and acidosis may occur), and in later childhood and adolescence (when the management of neurogenic bladder or complications of previous repairs of the anorectal anomaly are important).

Acidosis↗

Segmental renal vein renins and partial nephrectomy for hypertension in children.

Hypertension in children often is curable surgically. In many instances the causative lesion will be segmental and either vascular or parenchymal. We report on 5 children with a segmental lesion in whom the elevated segmental renal vein renins correctly predicted cure of the hypertension following partial nephrectomy.

Adolescent↗

Unilateral multicystic renal disease in adults.

Patients with multicystic kidneys that remained undetected for many years are currently our best source of information on the long-term fate of this type of renal dysplasia. We review 24 cases with adequate data reported in the literature and add 3 personal cases. Significant problems that were encountered and were related to these retained multicystic kidneys include abdominal pain, erroneous diagnosis of renal agenesis leading to repeated unrewarding medical studies for abdominal pain, abdominal mass and renal neoplasm arising in the dysplastic kidney.

Adult↗

Electronic bladder stimulation in the management of children with myelomeningocele.

Mentor electronic bladder stimulators were implanted in 8 children with myelomeningocele who were being managed successfully with intermittent catheterization. Satisfactory clinical performance was obtained in only 3 of these children. In the 5 failures urine flow was sporadic and unreliable. In 6 patients electrode lead wires broke where they entered the anterior abdominal fascia. None of the 8 units functioned more than 29 months. Many technical problems must be resolved before bladder stimulators will have a significant role in the management of children with myelomeningocele.

Adolescent↗

Observations on the small kidney associated with vesicoureteral reflux.

Of 63 patients with reflux and renal atrophy renal dysplasia was found in 9.5 per cent. Pyelonephritis was apparent in 81 per cent of the atrophic lesions. Urinary obstruction or ectasia was apparent in each case with dysplasia and only 2 were associated with histologic evidence of pyelonephritis. Pyelonephritis appears to be a major causal factor in atrophy occurring in renal units with reflux. Early urinary tract obstruction or distension may predispose to renal dysplasia.

Adolescent↗

Importance of cystourethrography in neonates with imperforate anus.

Infants born with imperforate anus have a high incidence of genitourinary anomalies. Vesicoureteral reflux was the most common abnormality in this series. Since these patients often have bacteriuria, this is an important finding. An intravenous pyelogram and voiding cystourethrogram should be part of the evaluation of each neonate with imperforate anus. Persistent cloaca, a frequent finding in the female patients, may require special diagnostic attention.

Anus, Imperforate↗

Observations on the small kidney associated with vesicoureteral reflux.

Of 63 patients with reflux and renal atrophy renal dysplasia was found in 9.5%. Pyelonephritis was apparent in 81% of the atrophic lesions. Urinary obstruction or ectasia was apparent in each case with dysplasia and only 2 were associated with histologic evidence of pyelonephritis. Pyelonephritis appears to be a major causal factor in atrophy occurring in renal units with reflux. Early urinary tract obstruction or distension may predispose to renal dysplasia.

Adolescent↗

Reconstruction of the urinary tract in prune belly uropathy.

Ten patients with prune bell uropathy, including 7 neonates, were treated with extensive surgical tailoring of the upper urinary tracts using primarily the upper ureteral segment. Simultaneous transabdominal orchiopexy, particularly in the neonate, is described as a useful adjunct. Our early results in these patients justify this aggressive approach.

Abdominal Muscles↗

Orchiopexy in the prune belly syndrome.

It has been suggested that abdominal testes might have better ultimate function if brought to the scrotum at a very early age. In a study of 16 patients with the prune belly syndrome, 8 had reconstruction of the urinary tract together with an orchiopexy and 2 had an orchiopexy alone. The results in these patients support the view that an orchiopexy in the neonate or young infant offers the best chance of obtaining viable testes in the scrotum.

Abdominal Muscles↗

Urologic implications of imperforate anus.

Recent clinical studies have documented the high association of genitourinary and lumbosacral spine anomalies with imperforate anus. Many of these associated anomalies may go undetected unless special diagnostic studies are performed, and these genitourinary anomalies can be the cause of significant clinical morbidity in later life if not managed properly initially. All neonates with imperforate anus should therefore undergo radiographic examination with lower spine films, intravenous pyelography and voiding cystourethrography, and cystoscopy should be reserved for those with cloaca deformity or those whose x-ray films demonstrate urinary anomalies requiring further workup. Significant morbidity involving the genitourinary tract may be encountered after surgical treatment of the anorectal anomaly, particularly if total anorectal reconstructions are performed in the neonatal period.

Allantois↗

Obstructive uropathy in the neonate: the case for early definitive correction.

Recently, early temporary supravesical urinary diversions undoubtedly have saved the lives of many neonates with severe obstructive uropathy. These procedures will continue to have an important role in the management of such patients. However, the initial success of these procedures should not obscure the difficulties that they might initiate in the ultimate rehabilitation of the urinary tract. In many instances it may be safer and more reliable to carry out a primary, definitive, corrective procedure initially.

Female↗

Hypernephroma in children.

Two cases of childhood hypernephroma are presented, bringing to 88 the number of cases of this unusual tumor authenticated in the literature. Both children were black males, four and eight years old. Both had Stage II right renal lesions which were treated with radical nephrectomy and postoperative irradiation. One has been followed up for over seven years and is free of disease. A brief summary of the incidence, treatment, and prognosis of this unusual childhood malignancy is presented.

Adenocarcinoma↗