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Biomedical subjects

T Robak

Publications and source records attributed to T Robak.

At least 253 records · Page 14Linked to original sources
PubMedDate not supplied

[Proportion of B- and T-lymphocytes in lymph nodes removed from patients with Hodgkin's disease].

The proportions of T and B lymphocytes were determined in lymph nodes removed from 30 patients with Hodgkin's disease and in 18 control lymph nodes. In all lymph nodes obtained from patients with Hodgkin's disease histological examination demonstrated presence of typical granulation tissue of type Ns, Mc, Ld (changes of Lp type were not found). In the control lymph nodes no neoplastic changes or inflammatory reactions were observed. For identification of T cells the rosette test E was used and for identification of B cells --- the EAC rosette test and tests for presence of Ig on their surface by the immunofluorescent method (L Ig+). It was found that the proportions of T and B cells in the lymph nodes obtained from patients with Hodgkin's disease were not different from those in control lymph nodes. The percent values of T and B cells were similar in all three histological types of changes in Hodgkin's disease. Early radiotherapy was not connected with a change in T and B cell proportions in the irradiated lymph nodes.

B-Lymphocytes↗
PubMedDate not supplied

[Various immunological phenomena in myasthenia gravis. Preliminary report].

The proportions of subsets of T and B lymphocytes and their counts were determined in the peripheral blood in 15 patients with myasthenia. The blastic transformation of these cells was studied after stimulation with mitogens: PHA, Con A and PWM. The serum immunoglobulin level was determined as well. In five thymectomized patients these investigations were repeated during up to two years after the operation. The comparison of the results of these tests in the patients and healthy controls showed differences only in the ability to respond with blastic transformation of the lymphocytes to PHA and Con A. This ability was reduced in some patients with myasthenia. Investigations repeated after thymectomy failed to demonstrate changes in the proportions and counts of T and B lymphocytes, degree of blastic transformation and immunoglobulin levels in relation to prethymectomy values.

Adolescent↗