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Biomedical subjects

T Rivera

Publications and source records attributed to T Rivera.

26 records · Page 2Linked to original sources

[Hearing screening in children with risk factors of hearing loss in the area 3 of Madrid].

The early identification of the hearing loss is very important to begin a early rehabilitation and to get a normal development of the language. Because of reason, the newborn hearing screening started, mainly in cases with risk factors. The objective of this report is to study the incidence of hearing loss in children with risk factors in the area 3 of Madrid. We realized hearing screening in 138 children in a period of 3.5 years, by otoacoustic emissions in younger 1 year and auditory brain stem evoked response in older 1 year. The results show that the incidence of sensorineural hearing loss is 4.34% of cases in children with risk factors, and more specifically 2.8% of bilateral profound hearing loss, and too, we detected 6.5% of transmisive hearing loss. The age of identification of hearing loss decreased to 6 months with the hearing screening programs. These results support the need of realization of hearing screening programs with obligatory character, though we advocate for the universal screening to include all cases of hearing loss without risk factors.

Algorithms↗

Seroepidemiological and clinical study of Chagas' disease in Nicaragua.

With the aim of determining the prevalence, immunological profile, and knowing the electrocardiographic alterations, a clinical and seroepidemiological study of Chagas' disease was performed in three rural settlements located at the North, East and West of Nicaragua. Anti T. cruzi antibodies were searched by indirect immunofluorescence (IFI) and hemagglutination (IHA) in a total of 803 subjects. Seropositives and the same number of seronegatives, matched by age and sex, were included in a case-control design for the electrocardiographic assessment. Antibody prevalence was 13.1, 4.3 and 3.2% in the respective settlements. In the first two the immunological profile corresponds to that of an endemic zone of long standing, were transmission has decreased, and in the third the pattern is of a zone under control. Electrocardiographic changes compatible with Chagas' disease were found in seropositive individuals, but difference with control group was not statistically significant. It is concluded that the disease is endemic in the three settlements and the clinical aspect requires further evaluation, including additional cardiologic techniques.

Adolescent↗

[Sudden deafness: efficacy of a therapeutic protocol].

Sudden hearing loss is an entity of unknown cause. Different theories of its etiology and treatment have been proposed. The objective of our report is to evaluate the efficacy of the therapeutic protocol used in our department in patients with sudden hearing loss. We made a retrospective study of 24 patients who had experienced sudden hearing loss from January 1994 to March 1998. We studied the parameters of age, sex, days of hospitalization, vestibular symptoms, otoscopy, personal history, radiology study, and successive audiograms. The treatment protocol consists of low-dose steroids, pentoxyphylline, and carbogen, and a concentration of 5% CO2 and 95% O2. Treatment was effective, with a recovery rate of 83%. The factors of tinnitus or vertigo, the state of hearing in the opposite ear, and age did not influence the recovery of hearing. However, the form of the audiogram and initial hearing were important prognostic factors.

Adolescent↗

[Usefulness of laryngeal stroboscopy].

The extended use of optic fibers and TV cameras and videos make easier the stroboscopic exploration of the vocal folds. The ENT surgeons must stress the use of this unique method which allows us the study of the laryngeal voice function. This exploration is based on a fictional slow motion movement of the vocal fold that lets us see the mucosal wave. The most useful clinical implications of the laryngeal stroboscopic study are: phonatory function, differential diagnosis between benign and malignant lesions and laryngeal paresis.

Biophysical Phenomena↗

Receptivity disorders in gonadal dysgeneses. i. Klinefelter's syndrome.

Long-term variation (21-30 days) in the gonadotropic hormones level and testosterone was followed up in Klinefelter's syndrome (chromatine positive). Clinically, the authors followed up the development of the androgen-dependent target tissues before and after administration of 400 mg testosterone/month for 6 months. It was also found a fluctuation in the gonadotropic hormones secretion on a 21-30-day trial which differs from that of the normal adult male. We noticed a great variability of the androgen-dependent structures development in one and the same subject or in different subjects, and a low response to the action of big and prolonged doses of testosterone. The authors interpret these findings as a decrease in the sensitivity of the androgen-dependent target structures (hypothalamus and peripheral tissues) induced genetically and fundamenting the concept of the existence of a receptivity pathology.

Adolescent↗

[S/z ratio in glottic closure defects].

The quotient between the maximum phonation time (MPT) of the sound /s/ and a vowel sound, measures the relation of resistances to the expiratory air flow. When the sound /s/ is emitted, resistance is located at the teeth, and when a vowel is phonated, the site of resistance is the glottis. Estimating the quotient instead of measuring only the MPT, we avoid the influence of respiratory alterations in the results. We evaluated the utility of the s/z ratio as a clinical indicator of laryngeal pathology in 72 patients with organic vocal cord pathology. We compared the results of the s/z ratio to the degree of glottic closure defect, measured by videolaryngostroboscopy. S/z ratio in 22 normal-speaking subjects was also measured. S/z ratio in normal-speaking subjects was nearly 1.0. When a glottic closure defect was present, the ratio was over 1.4. Organic lesions that difficult glottic closure, produce a decrease of air flow resistance and, therefore, a shortening of the MPT of the vowel sounds.

Adolescent↗

[Pathophysiological basis of aminoglycoside-induced ototoxicity].

Recently proposed etiopathological mechanisms of aminoglycoside-induced toxicity were reviewed, including calcium, phosphatidylinositol, Na-K dependent ATPase, and neuronal sites of antibiotic action. Difficulties in evaluating the true clinical incidence of this aminoglycoside-induced ototoxicity and risk factors were analyzed. The relation between new dosing regimens (single daily dose) and ototoxicity are discussed.

Aminoglycosides↗