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T Ribeiro

Publications and source records attributed to T Ribeiro.

36 records · Page 2Linked to original sources
PubMed1998

[Hepatic schistosomiasis: diagnostic difficulties in a non endemic area].

Schistosomiasis is a major cause of liver damage and portal hypertension, especially in tropical countries, affecting about 200 million people in the world. We report the cases of two patients presenting persistent alterations of serum liver enzymes. We enhance the importance of considering the history of past travels and a liver biopsy to diagnose an infrequent parasite induced liver disease in a non endemic area such as Portugal. Some observations are made about the diagnosis and treatment of this parasitic disease.

Biopsy↗
PubMed1998

[The first assessment of hepatitis E virus seroprevalence in northern Portugal].

Hepatitis E is an enterically transmitted acute viral hepatitis, etiologically associated with a recently characterized virus, the hepatitis E virus (HEV). Outbreaks mainly occur in developing countries and as sporadic cases in endemic regions. The authors present the first serological assessment in northern Portugal to assess the presence of anti HEV IgG, using the Elisa test, the EIA and HEV Abbott, in samples from 50 blood donors and 103 chronic liver disease patients. In 2 blood donors (4%) and in 7 (6.8%) liver patients, the HEV antibody was detected with optic densities/cut off always below 2.5. Only one patient had a sojourn in an endemic region; the presence of anti-HEV was not significantly associated with other hepatotropic viruses. With this test the authors conclude that 4% of our blood donors are seropositive for anti-HEV antibody and that this percentage is not significantly higher in chronic liver disease patients (6.8%). They also think that a new generation of immunological assays, designed for serological diagnosis of HEV infection, will provide a further understanding of hepatitis E epidemiology.

Adult↗
PubMed1998

South Portuguese population data on the loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc.

Five South Portuguese Caucasian subpopulations were analyzed for the HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc loci. Genotype distributions for these loci did not deviate from Hardy-Weinberg expectations. The allele and genotype frequencies found have been compared with previously published data from North and Central Portugal. A total of 11 out of 138 chi-square comparisons of allele frequencies between different Portuguese populations showed a certain degree of divergence. Alentejo, Algarve, Madeira Island and Azores Islands populations might be considered as different groups in a database. For forensic casework, a composite South Portuguese Caucasian population database was obtained for estimating multiple locus profile frequencies using the six PCR-based loci studied.

Alleles↗
PubMed1997

[Ethics, science and utilitarianism].

We begin this article with the distinction between Deontology, Moral and Ethics. We also review the concept and the relevance of Bioethics, as the "science of survival", and as part of Ethics, a section of Philosophy. We tried to answer two further questions considering the role of Science in orienting Ethics, or the possible place of utilitarianism in controlling Ethics. The author discusses some new aspects of the doctor/patient relationship, and their evolution in the last 100 years, as well as the relations between patients and Health care institutions. Some ethical problems were also raised related to the beginning and the end of life. Finally the author reflects on the difficulties of defining ethical concepts in the near future.

Ethics, Medical↗
PubMed1994

Treatment of acute diarrhea with oral rehydration solutions containing glutamine.

OBJECTIVE: In a randomized, double-blind, controlled clinical trial we compared the efficacy of adding 90 mmol/L L-glutamine to the standard World Health Organization oral rehydration salts (WHO-ORS). SUBJECTS: One hundred twenty male infants, > 1 month and < 1 year of age, with acute non-cholera diarrhea and dehydration were randomly assigned to one of the two treatment groups. METHODS: Patients were kept in a metabolic unit where body weight, ORS, water and food intake, as well as stool, urine and vomitus output were recorded at 6-hour intervals. Laboratory evaluation, including blood gases and electrolytes, were monitored during hospitalization. RESULTS: Diarrheal stool output, duration of diarrhea and volume of ORS required to achieve and maintain hydration was not significantly different between the treatment groups. CONCLUSION: This study demonstrated that a glutamine-based ORS did not provide any additional therapeutic advantage over the standard WHO-ORS during treatment of dehydration in infants with acute non-cholera diarrhea.

Acute Disease↗
PubMed1971

[Comparison of the proteins in pancreatic juice in normal and diseased humans. Determination of serum proteins and demonstration of a particular protein in chronic calcifying pancreatitis].

For a better understanding of the molecular mechanism leading to intraductal precipitation of proteins in primary chronic calcifying pancreatitis in man, we studied the composition of normal and pathological human pancreatic juice by immunotechniques. We found an increased level of serum proteins in pathological juices: 12.47% of total proteins compared to 1.8% in normal ones; albumin is 8.16% of the total proteins, IgG 2.84%, IgA 0.83% and IgM 0.91%. Transferrin and alpha 2-macroglobulin are present, but were not estimated. The albumin/IgA and albumin/IgG ratios favour the hypothesis of a local synthesis of these immunoglobulins as was shown in normal juice. The cross adsorption of antisera against pancreatic juice showed the presence in the pathological juice of a normal molecule in much higher concentration. The role of these proteins in precipitation is discussed.

Albumins↗