Search PubMed⌕ Search

Biomedical subjects

T R Rao

Publications and source records attributed to T R Rao.

At least 37 records · Page 2Linked to original sources
PubMed1984

DNA sequences from a ligninolytic filamentous fungus Phanerochaete chrysosporium capable of autonomous replication in yeast.

Five different DNA sequences of Phanerochaete chrysosporium capable of supporting autonomous replication of yeast integration plasmid (YIp5) in Saccharomyces cerevisiae were isolated. These hybrid plasmids with the autonomous replication sequences from P. chrysosporium are maintained extra-chromosomally, are mitotically unstable and transform Ura3 deletion mutant of S. cerevisiae to Ura+ phenotype with high frequency. The autonomous replication sequence in pRR2, one of the recombinant plasmids, was further characterized and was shown to be homologous to P. chrysosporium genomic DNA. Restriction analyses showed that this plasmid has unique PvuII and SalI restriction sites for cloning.

Base Sequence↗
PubMed1982

Colorectal linitis plastica.

Primary linitis plastica of the colon is an uncommon tumor, with only 22 cases having been previously reported. Experience with two men and one woman between 17 and 55 years of age, portraying a spectrum of clinical presentations ranging from rectal bleeding to large-bowel obstruction, is reviewed. Clinical and radiologic characteristics and histologic features helpful in making the diagnosis are detailed. Though the prognosis is grim, resective surgery, including oophorectomy in women, should be undertaken. Adjuvant therapy has been disappointing.

Adenocarcinoma, Scirrhous↗
PubMed1979

Jejunoaortic fistula from ingested seamstress needle.

A 27-year-old man was evaluated for sudden onset of massive hematemesis and hematochezia. A bleeding site was not seen on esophagogastroduodenoscopy. There was little blood in the stomach, which suggested that the bleeding site was below the ligament of Treitz. Angiography demonstrated the presence of an intra-aortic metallic foreign body that resembled a sewing needle. At operation, a chronic jejunoaortic fistula that contained the sewing needle was found and repaired. The patient had no recollection of having swallowed the needle, and it is presumed that he ingested it in infancy. He had an uneventful recovery.

Adult↗
PubMed1976

Primary malignant melanoma of the hard palate.

A case of malignant melanoma of the oral cavity is presented. The very high frequency of squamous cell carcinoma of the palate in Visakhapatnam, India, is compared to the rarity of malignant melanoma, even though pigmentation of the oral cavity is quite common in this geographical region.

Humans↗
PubMed1975

Gastric acid secretion in pancreatic disease.

Gastric acid secretion studies were carried out in 48 patients with pancreatic disease and in 20 control subjects. The mean basal and maximal outputs were lower in the patients than in control subjects. The present study indicates that such patients are not likely to suffer from gastric hypersecretion and peptic ulceration.

Adolescent↗
PubMed1973

Breeding places and seasonal incidence of Aedes aegypti, as assessed by the single-larva survey method.

The single-larva survey method was employed to study the breeding places and seasonal incidence of Aedes aegypti in Dar es Salaam, Tanzania. From May 1968 to May 1969, 28 462 containers of water-located in approximately equal numbers indoors and outdoors-were investigated. The highest frequency of breeding (8.0%) of A. aegypti was observed in tires and motor parts. Drums, barrels, water-pots, and other receptacles left outdoors showed a higher frequency (3.1%) than those kept indoors (0.6%). Metal containers were infested to a greater extent than those made of mud, wood, or other materials; 2.5% of coconut shells, snail shells, etc. and 1.3% of tree holes, plant axils, and cut bamboos were infested. The seasonal prevalence, expressed as a container index, closely followed and paralleled the fluctuations in rainfall. The value of this survey method for both ecological studies and practical control purposes is discussed.

Aedes↗
PubMed1973

Diel periodicity in the landing of Aedes aegypti on man.

The dynamics of transmission of disease agents by vectors depends, in part, on the probability of host-vector contact, which can vary with fluctuations of both host and vector. As important as seasonal variations is 24-hour periodicity in activity. Periodicity in the landing of males and females of Aedes aegypti on man has been assessed by means of catches of 15 hours or longer, with several persons as a bait. The assessments were made in a suburban area of Tanzania and continued throughout one year. Activity was observed to be almost entirely diurnal and diphasic. Whereas the detailed activity pattern of males agreed closely with that found elsewhere in East Africa, that of the females was unusual on account of the symmetry of the morning and afternoon peaks. Possible causes of differences among studies are discussed.

Aedes↗
PubMed1971

Immunological surveys of arbovirus infections in South-East Asia, with special reference to dengue, chikungunya, and Kyasanur Forest disease.

Serological surveys have been widely used in South-East Asia to determine the presence and activity of arboviruses. The haemagglutination-inhibition test has been most frequently employed but complement-fixation and neutralization tests have also been used in some investigations.Although virus isolations provide the most conclusive evidence, they can be carried out in a few specialized centres only, and serological surveys are very important for studying the distribution of arboviruses.The surveys have shown that group B arboviruses (principally all four types of dengue, Japanese encephalitis, and West Nile) are widely prevalent. Dengue and Japanese encephalitis viruses are more widespread than West Nile virus, which was not known previously to extend east of India although recent survyes have shown that its range extends to Burma. Japanese encephalitis is frequent in most of South-East Asia but in India is found mainly in eastern and south-eastern parts of the country. Kyasanur Forest disease (KFD) and Langat viruses are the only tick-borne group B arboviruses definitely known to occur in the region, the former in India, the latter in Malaysia. KFD virus has been isolated only from a small focus in Mysore, although human and animal sera containing neutralizing antibodies to this virus have been found sporadically in widely scattered areas. Among the group A arboviruses, chikungunya and Sindbis have been detected in serological surveys, but the former has not yet been found in Malaysia.

Adolescent↗