[Adverse effects and interactions in therapy with psychopharmaceuticals].
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Biomedical subjects
Publications and source records attributed to T R Payk.
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As in other medical fields there also exist psychosomatic diseases in urology which appear in the form of functional disturbances. Besides alterations of the diuresis, mainly an irritable bladder, symptoms of enuresis, urinary retention and additionally symptoms of chronic prostatitis and disturbances of sexual potency. In order to explore the psychic etiology usually a psychiatric examination is necessary with the aim to start adequate treatment.
30 patients suffering from therapy-resistant chronic pain were divided into three groups according to drive and mood: I. psychomotor inhibition combined with depressive mood, II. agitation and depressive mood, III. agitation combined normal mood. The psychopharmacological treatment of pain showed sufficient results, when the drugs were directed to the target symptoms "agitation", "lack of drive", and "depression". The differentiated administration of activating or sedative antidepressants and neuroleptics caused reduction or absence of pain while the routine administration of neuroleptics (i.e. chlorpromazine) was less effective.
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Although there exists a voluminous biographic literature on Robert Schumann, there are only few informations on the last 2 years of his life, which he spent in the sanatorium Endenich near Bonn/Rh. Schumann, suffering from a recurring psychosis since 1833 at least, had been received there after a suicidal attempt on March 4th, 1854. His physical and psychical state deteriorated permanently and Schumann died on July 29th, 1856, somatically and mentally disordered. Up to now there exists no clear diagnosis, but there is every reason to believe that Schumann was suffering from a schizophrenic psychosis, combined with a cardiac and circulatory disease.
Already in the normal state of health often there are alterations of subjective time experience both as acceleration and delay of the lapse of time. These impairments of time perception are more important in the psychopathological field. Except during organic brain disease disturbances of time experience are observed especially during endogenous psychoses. Depressed men usually feel an unpleasant extension of subjective time experience. In schizophrenia there is a specific distorsion of time, characterized by troubles of the biographic orientation, by magic connexion-thinking with regard to time, or by a "collapse" of the chronological order. Somatic as well as psychological conditions seem to cause these disturbances.
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First the terms "impulse" (Antrieb) and "schizophrenic defect" (schizophrener Defekt) are explained and defined. 49 (= 12 per cent) of the 409 schizophrenic in-patients, treated 1970-1972, had the symptoms of a schizophrenic defect. All of them showed disturbances of impulse: more than half the patients a deficiency, nearly a third an unsettled surplus, and about ten percent an alternating impulse. The deficiency as the alternating impulse usually were accompanied with a negativ mood. The surplus of impulse was bound up as equal parts with positive and negative moods. At last any kind of disturbances of described is illustrated by an example.
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