Biomedical subjects
Publications and source records attributed to T R Graham.
Optimising the management of the heart-lung donor may increase the number of organs suitable for transplantation. This can be achieved by understanding the pathophysiology of brain death and implementing therapeutic measures to counteract the deleterious effect of brain death on end-organ function.
Mechanical support of the circulation using intra-aortic balloon counterpulsation has thus far largely been confined to cardiac units. With improved techniques of insertion, many critically ill patients may now benefit. This article reviews the physiology of counterpulsation, the indications and contraindications for its use, and the complications that may occur.
Sternal fractures have become more common since the introduction of seat belt legislation. However, the injury often heals well with minimal or no sternal deformity. Morbidity and mortality in patients with fractures of the sternum are usually due to other organ injuries.