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Biomedical subjects

T R Barnes

Publications and source records attributed to T R Barnes.

102 records · Page 6Linked to original sources

Sub-syndromes of tardive dyskinesia.

A reliable method for recording the site and duration of purposeless movements was devised. With this method 267 subjects were studied, 182 of whom had been exposed to neuroleptics. The results were submitted to a principal components analysis and 3 movement dimensions emerged. One group of movements resembled a parkinsonian syndrome. The other 2 groups of movements both conformed to the generally accepted criteria for tardive dyskinesia. These groups were: (1) head and neck movements and (2) trunk and limb movements. The possibility of the second and third groups representing clinically relevant sub-syndromes of tardive dyskinesia is discussed.

Dyskinesia, Drug-Induced↗

Relationship between visually based food preference and amount eaten.

29 male and 44 female undergraduates were given a rod-and-frame test and allowed free access to white and colored cookies. Rod-and-frame scores were higher for females than males but were not related to percentage overweight. The ratio of white to colored cookies chosen was related to total cookies eaten. The theoretical implications of these results are then considered.

Choice Behavior↗

Dysphoric and depressive symptoms in chronic schizophrenia.

This study suggests that depressive symptoms are less common in severe, chronic, schizophrenic inpatients than would be predicted if these symptoms were manifestations of negative symptoms or drug-induced parkinsonism. The findings further suggest that depressive symptoms in such patients are independent phenomena which conform to a depressive syndrome. This depression does not represent a misidentification of the negative symptoms affective flattening and alogia, as measured by the SANS, or parkinsonism or akathisia. The study findings fail to support the view that long-term depot antipsychotic medication plays an important role in the genesis of depression and dysphoria in chronic schizophrenic patients. Depressive symptoms were found to occur as frequently, and dysphoria more frequently, in schizophrenic patients in the year after drug withdrawal compared with patients continuing on maintenance drug treatment for the same period.

Administration, Oral↗