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Biomedical subjects

T R Anderson

Publications and source records attributed to T R Anderson.

49 records · Page 3Linked to original sources
PubMed1975

Sympatho-adrenal development in perinatally addicted rats.

Chronic morphine administration in adult rats results in neurogenic secretion of adrenal catecholamines and compensatory increases in basal catecholamine levels, in activities of catecholamine biosynthetic enzymes and in the number of storage vesicles in the tissue. Perinatally addicted developing rats demonstrated changes completely different from those seen in adults; catecholamine levels and dopamine beta-hydroxylase activity were reduced compared to controlscsnnofinduction of tyrosine hydroxylase was observed. The time course of adrenomedullary maturation was delayed throuth the first 10-20 days of age, with reduced numbers of storage vesicles and larger proportions of partially filled vesicles. On exposure to morphine, continued until weaning, perinatally addicted rats did not display any of the changes in catecholamine synthesis or uptake seen in adult rats. The differences between adults and developing rats can be partly explained by the absence of functional innervation of the neonatal adrenal medulla.

Adrenal Medulla↗
PubMedDate not supplied

Mapping genes conferring resistance to Phytophthora root rot of soybean, Rps1a and Rps7.

A linkage map was constructed for two Phytophthora sojae Kauf. +Gerd. root rot resistance genes, Rps1a and Rps7, in soybean (Glycine max (L.) Merr.) using microsatellite or simple sequence repeat (SSR) markers. An F2 population consisting of 81 individuals derived from a cross between OX281, which carries Rps7, and Mukden, which carries Rps1a, was used as the mapping population. A linkage map consisting of 10 SSR markers was first constructed using the computer software MapMaker/EXP 3.0. Rps1a and Rps7 were then placed at two different loci in the same linkage group with LOD scores of 2.88 and 9.16, respectively. Rps1a and Rps7 were linked at a distance of 13.8 cM. Rps1a was flanked by Satt159 (0.7 cM) and Satt009 (3.2 cM). Rps7 was flanked by Satt009 (10.6 cM) and Satt125 (29.1 cM).

Chromosome Mapping↗
PubMedDate not supplied

The accuracy of absolute localization judgments for speech stimuli.

Communication signals are likely to be one of the primary forms of acoustic stimulation within three-dimensional auditory displays, yet the ability to localize these signals has received relatively little study. We investigated the ability to localize single-word speech targets, spoken by one male and one female talker, as compared to the ability to localize click targets. On each trial, the targets could arise from any one of 239 speaker locations that surrounded the subject in azimuth and ranged from -45 degrees to +90 degrees in elevation. The results showed that localization accuracy relative to the median plane (the Left/Right dimension) was good for both the speech and nonspeech targets. However, with speech targets, there were more front/back reversals (inaccurate judgments relative to the frontal plane, the Front/Back dimension) and typically less accurate elevation judgments (inaccurate judgments relative to the horizontal plane, the Up/Down dimension) than were found with click targets. These results have important implications for applications of spatial hearing technology and suggest that need for caution when designing three-dimensional auditory displays in order to assure that spatial information is conveyed appropriately.

Acoustic Stimulation↗