Search PubMed⌕ Search

Biomedical subjects

T Pottecher

Publications and source records attributed to T Pottecher.

72 records · Page 4Linked to original sources
PubMed1984

Thrombogenicity of central venous catheters: prospective study of polyethylene, silicone and polyurethane catheters with phlebography or post-mortem examination.

The thrombogenicity of polyethylene, silicone and polyurethane central venous catheters was compared in a prospective clinical, phlebographic and post-mortem study in 52 patients. The incidence of central venous thrombosis was high with polyethylene catheters (70%), but much lower with silicone (20%) and with polyurethane catheters (17%).

Catheters, Indwelling↗
PubMed1981

[Haemodynamic investigation in pre-eclampsia or eclampsia. Consequences of therapy (author's transl)].

Haemodynamic function was assessed in twenty patients with severe pre-eclampsia or eclampsia. In front of the earlier well-known data hypercinetic circulatory status was found with vascular resistance almost unchanged. As some investigators found two levels placental blood flow, haemodynamic status may be different in some cases. Consequences on therapy are discussed especially beta-bloquers and potential deleterious effects of anti-hypertensive treatments.

Adolescent↗
PubMed1981

[Stress-ulcer. Prevention and therapy by cimetidine (author's transl)].

Efficiency of cimetidine in therapy and prevention of stress ulcer has been tested in a double blind study with endoscopic examination at the time of inclusion and a week later. This study concerns forty patients with severe cerebral disorders and prolonged coma. In preventive group (20 subjects) we noticed 55 p. cent of success under placebo and 37 p. cent with cimetidine. In therapy group (20 subjects) cimetidine was not different from placebo (37,5 of success v. s. 41,25 p. cent). Two patients presented hematemesis. The relative failure of cimetidine in these patients is discussed and some explanations are envisaged.

Adolescent↗
PubMed1981

[The infusion of packed red cells. Usual difficulties (author's transl)].

This infusion used instead of whole blood has become increasingly common. However in our, as in other french institutions, the volume and the hematocrit of blood contained in each unit varies often notably. In addition, because of their high viscosity packed erythrocytes cannot be transfused rapidly enough. For transfusion in emergency situations and transfusion in operating room, following suggestions could be made to blood banks: --each unit should provide information on its content (volume and hematocrit or hemoglobin content); --units with low blood content should be transfused outside the operating room, whereas units containing high volumes should be reserved for peroperative transfusion in order to reduce charge of manipulation; --packed erythrocytes units should be prepared in order to allow same transfusion rates as whole blood (i.e. an average of 100 ml per minute for one transfusion line); --packed erythrocytes units should contain about 80 ml of plasma for an average total concentrate volume of 260 ml in order to provide enough antibacterial defense components; --units of fresh whole blood should be provided when approximately 150 p. cent of recipient's blood volume has been replaced in order to maintain the critical platelet level.

Blood Sedimentation↗
PubMed1980

[Post-traumatic myocardial injuries (author's transl)].

Myocardial injuries are often misknown because of hard diagnosis. After presenting two clinical cases, this paper concerns clinical and biological criteria used to prove post-traumatic myocardial injury. Increased serum level of M.B. fractions of C.P.K. associated with typical electrocardiographic aspect is enough; other investigations are less specific and may be hasardous to attempt. Prognosis and therapy are close to acute myocardia infarction.

Aspartate Aminotransferases↗
PubMed1979

[Mortality factors in infectious diseases in a surgical intensive care unit].

Among 350 patients admitted to a surgical intensive care unit between 1.1.77 and 31.9.77, their profile and septic course being defined, two populations were studied: -- the first involved 49 patients dying of infection during their stay in the department; -- the second involved 132 patients developing a non lethal infectious syndrome. Comparative study of these two patients groups made it easier to understand why, in the same department and apparently with the same kind of care, certain patients die of infection and others do not. It was thus attempted to demonstrate certain difference between the two groups in terms of biometric data, predictable risk factors, the type of underlying pathology and the nature and course of the infectious process. Finally, the role played by the intensive care unit in the onset of these deaths of infectious cause is considered.

Adolescent↗
PubMed1977

The use of aminophylline for correction of haemodynamic repercussions of clamping of the aorta.

Occlusion of the abdominal aorta induces an increased impedance to ejection, leading to a reduction in cardiac output. The magnitude of the haemodynamic disturbances seemed important enough to justify the use of a vasodilator drug. In that respect the use of aminophylline was evaluated in twelve patients. The potentially dangerous increase in systemic resistance is prevented by aminophylline, which effectively neutralizes the increase in afterload. Moreover, a positive inotropic action can be inferred from the increase in stroke volume and ventricular systolic work. It must be stressed that this drug must be withheld in patients with cardiac irritability, for it has a beta-mimetic action.

Aged↗
PubMed1977

Haemodynamic changes due to clamping of the abdominal aorta.

Haemodynamic changes due to aortic cross-clamping were examined in 18 patients. It has been shown that the distal occlusion of the abdominal aorta induces an increased impedance to ejection. Because the mechanisms controlling the auto-regulation of cardiac output and the circulatory reflexes are damped by anaesthesia, the augmentation of resistance is not followed by any increase in contractility or vasomotor tone and thus the cardiac output falls. Patients with chronic obstructive disease (Leriche) did not differ significantly from subjects with more acute obstruction (aneurysm), though the latter have a tendency to show more important changes in their haemodynamic response.

Adult↗
PubMedDate not supplied

[Post-traumatic coma from diffuse brain lesions. A correlative study of the levels of dysfunction and the EEG nyctohemeral aspects (author's transl)].

Thirteen EEG and polygraphic recordings were performed during a 24-hour period in 11 patients with post-traumatic coma. Spontaneous fluctuations, reactivity, and the organization of electrical activity were studied throughout the nyctohemeral period. The results were compared with the data obtained from clinical examinations evaluated in terms of the level of neurological dysfunction. The level of impairment of the EEG was usually a valid indication of the level of neurological dysfunction, the EEG results being sometimes more precise than the clinical data. In regard to the prognosis, the disappearance in the EEG of any fluctuations coincided with an unfavourable evolution.

Brain↗
PubMedDate not supplied

[A comparative study of the cardiovascular effect of dobutamine. Preliminary results obtained in a surgical resuscitation unit].

Dobutamine (dobutamin hydrochloride, Lilly) is a new inotropic catecholamine; it is presented in lyophilized ampoules for I.V. use, each containing 250 mg of dobutamine to be reconstituted with 5 per cent glucose or sterile water for injection. In the first part of this study, animal pharmacology is reported as described in medical literature: inotropic activity with minimal chronotropic effects, direct action, no vasconstriction, minimal arrhythmogenic activity and minimal diversion of blood flow to skeletal muscles are the main experimental features. The authors report afterwards their own experience with dobutamine in 8 patients (cranial traumas) without cardiac failure, and in 9 patients presenting with a cardio-circulatory failure in a toxi-infectious condition. In all patients tested, hemodynamics parameters (heart rate, mean A.P., central venous pressure) and cardiac output measurement (dye dilution method) were performed. Cardiac index and systolic index, total systemic resistances, left ventricular performance were also calculated. Dobutamine dosage ranged from 2.5 to 10 mcg/kg/mn except in patients with low output syndrom (2.5 and 5 mcg/kg/mn). Dobutamine offers new possibilities by its constant and indisputable inotropic activity contrasting with its minimal chronotropic effect.

Animals↗