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Biomedical subjects

T P Ermolova

Publications and source records attributed to T P Ermolova.

14 recordsLinked to original sources

[Tuberculosis statistics by sectional data].

Analysis of sectional schedules and autopsy protocols for 1,061 persons who died of tuberculosis in Saint Petersburg in 1984-1991 has provided data on the age and sex distribution of the victims, the distribution of various types of tuberculosis as the underlying or concomitant disease, on the incidence and pattern of its complications, concurrent and competitive abnormalities and the causes of death. Comparison of previous results of the previous studies made regularly since 1981 has revealed stable and labile statistical parameters that characterize the evolution of tuberculosis as a disease, its pathomorphism in Saint Petersburg over the past century.

Adolescent↗

[The effect of prednisolone on the efficacy of the diagnosis of pulmonary cancer and tuberculosis].

The report describes a test intended to increase the efficacy and precision of cytologic diagnosis of lung cancer as well as bacterioscopic diagnosis of pulmonary tuberculosis. The test is run during examinations of sputum and pleural exudate. It uses prednisolone, per os, 30 mg daily, for 3 days, then sputum and pleural exudate are tested for cancer cells presence and/or mycobacteria of tuberculosis. A 100% diagnostic specificity of the test in diagnosing cancer and tuberculosis and unsophisticated procedures involved make the case for its application in all oncological, pulmonological and tuberculosis controlling institutions.

Bronchoalveolar Lavage Fluid↗

[Niobium powder--a new x-ray contrast medium for tracheobronchography].

In inhalation tracheobronchography with niobium powder in rabbits and a volunteer (physician), excellent contour bronchograms with detailed imaging of the structure of the mucosa were obtained. With methodically proper application the niobium particles of 20-40 microns do not penetrate into the alveoli and are quickly (within 1-5 days) eliminated from the bronchi. Investigations with mice have shown, that niobium powder is insoluble, does not irritate tissues and is not resorbed. It is also nontoxic.

Administration, Inhalation↗

[Morphological diagnosis of early cancer of the lung].

The evidence obtained at histologic study of 18 operative specimens from the middle lung involved by early cancer was compared to that obtained at cytological evaluation of the sputum, catheterization and bronchoscopy material. Combined cytologic investigation of the cells resulted in tumor identification in 15 cases, whereas bronchoscopic biopsy was efficient in only 5. The study of the tumor-adjacent bronchi revealed epithelial transformation which can be considered dysplastic. Dysplasia-typical cells recognized in the bronchial contents served the basis for entering relevant patients into the risk group.

Bronchi↗

[Potentials of the cytological method in the differential diagnosis of infiltrative processes of various etiology in the lungs].

Results of examination of 143 patients with the lung infiltrative lesions of various etiology (tuberculosis, carcinoma, acute pneumonia) are analysed. Cytological examination of the sputum, bronchial smears and lavage liquid allowed one to diagnose cytologically lung carcinoma in 67% and tuberculosis in 36% cases. Certain combinations of nonspecific cell elements in the bronchial content also helped to make the differential diagnosis between the infiltrative tuberculosis, carcinoma and acute pneumonia. The most informative is the examination of the lavage liquid.

Adolescent↗

[Cytological studies in pulmonary pathology].

Cytological investigations of the bronchial secretion and sputum in particular have acquired in recent years a great practical significance in pulmonary pathology. It is recommended to use cytodiagnosis along with prophylactic X-ray examinations of the population to detect pulmonary pathology, in particular among individuals with a higher risk of developing cancer. A substantiated opinion is put forward that cytodiagnosis should precede examinations of patients with clinico-roentgenologically confirmed changes in the lungs.

Adenoma↗

[Comparative evaluation of clinical, cytological and cell culture methods of candida vulvovaginitis diagnosis].

98 patients with Candida vulvovaginitis (CVV) were examined clinically, cytologically and culturally. Three clinical forms of CVV were distinguished: acute and subacute (26 and 23 patients, respectively)--before treatment, and remission (49 patients)--after treatment. The clinical diagnosis of CVV before the treatment was confirmed cytologically and/or in cultures (87.7%), in remission cytologically (4%), by cultures (20 patients). Candida in the phase of budding and pseudomycelium were prevalent in acute CVV (84.4%). In a subacute form Candida occurred in 30.3%, while in the remaining cases blastospores were observed. Significant correlation between the intensity of Candida colonies growth and phase of development on the mucous membrane was not found. Compared to the cultural method, the cytological technique is more cost effective, faster and simpler.

Candidiasis, Vulvovaginal↗