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Biomedical subjects

T P Bezverkhaia

Publications and source records attributed to T P Bezverkhaia.

At least 19 recordsLinked to original sources
PubMed1991

[Pathogenesis of arterial hypertension in diabetes mellitus].

To investigate pathogenesis of arterial hypertension in diabetes mellitus, the authors measured parameters of central and peripheral hemodynamics, basal renin levels, angiotensin, aldosterone, kallikrein-kinin system. The results were analysed with regard to hypertension type: essential (EH), atherosclerotic (AH) and nephrogenic (NH). Hypokinetic circulation, defected vascular elasticity, activation of renin-angiotensin-aldosterone system and hypoactivity of kallikrein-kinin system were characteristic of EH and AH. Most pronounced changes in peripheral hemodynamics and hypoactivity of depressor kallikrein-kinin system were seen in NH.

Adult↗
PubMed1991

[Androgen resistance related to receptor disorders].

It is the review of literature data on various phenotypic anomalies consequent to the absent or reduced ability of the target tissues to response to androgens (A) due to defects in receptor A structure and function. Clinical forms of resistance to A, quantitative and qualitative abnormalities in hormone-receptor interaction detectable in relevant patients are described as well as markers of target tissue sensitivity to A action suggested for use in prognosticating the response to A treatment.

Adult↗
PubMed1990

[The effect of thyroliberin on the blood level of gonadotropins and sex steroids in women suffering from Itsenko-Cushing disease].

The authors examined the level of gonadotropin (lutropin, follitropin) and sex steroids (estradiol, progesteron, testosterone) before and after administration of thyroliberin in 10 healthy women and 15 females suffering of Itsenko-Cushing disease. It was established that both the healthy and patients with Itsenko-Cushing disease did not reveal any significant changes in the level of lutropin, follitropin, estradiol, progesteron, testosteron after administration of thyroliberin within 2 hours of the examination. Data indicate absence of paradoxic response of gonadotropins and cells secreting sex steroids in Itsenko-Cushing disease.

Adult↗
PubMed1976

[State of the central regulation of glucocorticoid function of the adrenals in brain tumors].

Clinico-biochemical study of patients with tumours of the great hemispheres (75 observations) showed differences in the direction of reaction of the adrenal cortex to some actions. There was found a normal metopyron test, an inadequate activation in intensive stress action (an operation of removal of brain tumour) and a marked prolonged reaction to low stress stimulus (administration of low adrenaline doses). Several tests characterizing the function of negative reverse association mechanism and also reactions to stress actions of various intensity are necessary to assess the state of the central regulation of the glucocorticoid activity.

17-Hydroxycorticosteroids↗