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Biomedical subjects

T Oya

Publications and source records attributed to T Oya.

At least 37 records · Page 2Linked to original sources
PubMed1993

[New membrane filter (PORETEC) method for ocular diagnostic cytopathology].

We describe a new membrane filter (PORETEC) technique for processing cytopathologic fluid specimens. This procedure provides excellent cytologic preparations because there is no background staining and only a small amount of fluid specimen is necessary, as there is little cell loss. We compared the number of cells collected by the membrane filter technique with that collected by cytocentrifugation using conjunctival brush cytology specimens from 6 subjects. The number of cells obtained by the new method was significantly higher than that obtained by the cytocentrifugation technique. This method was very useful for ocular fluid specimens such as aqueous humor, vitreous specimens, and scrapings from the cornea and conjunctiva. We showed some examples of these specimens including immunocytochemical staining done by this method. We confirm that this is valuable for diagnostic cytopathologic study of various fluid specimens in ophthalmology.

Adult↗
PubMed1992

Characteristics and management of patients with fetal neuroblastoma.

At 35 weeks 6 days of gestational age, ultrasound evaluation of the fetal abdomen showed a mixed cystic mass in the superior pole of the left kidney. The mass was suspected to be an adrenal hemorrhage or neuroblastoma. The diagnosis was fetal neuroblastoma. Differential diagnosis enabled the fetal neuroblastoma to be distinguished from adrenal hemorrhage. The parameters of diagnosis of fetal neuroblastoma include no specific ultrasonographic pattern, lack of palpability, and no tumor markers. However, certain features do characterize fetal neuroblastoma, such as little metastases, complete resection at operation, and excellent prognosis. In cases of suspected neuroblastoma, a laparotomy performed as soon as possible is generally regarded as the best course of treatment. Nonetheless, biological analyses of the tumor may prove in the future to be necessary for determining whether or not laparotomy is the best treatment.

Adrenal Gland Diseases↗
PubMed1992

[Management of type A acute aortic dissection--results of the cases with thrombosed false lumen].

By reviewing the outcome, we studied the propriety of our principles for the treatment of type A acute aortic dissection in 45 patients, encountered during the 10-year period between 1981 and 1990. We conducted a comparative study of patients with a thrombosed false lumen (type T) and a patent false lumen (type P) to examine the effect of an acutely thrombosed false lumen on the prognosis of this disease. For the 25 patients treated in the first 6 years (1981-1986), operation was performed as soon as exact diagnosis was made, regardless of the presence of complications and the type or severity of the disease. Early death occurred in 9/20 operated cases and in 4/5 unoperated cases, so 13/25 patients died for a 52.0% mortality rate. For the 20 patients who received treatment in the latter period (1987-1990), we gave priority to conservative treatment for type T cases that were free from complications, and adopted a treatment method attaching greater importance to the resection of intimal tears. As a results, early deaths were observed in only 4 type P patients (20.0%) who underwent operation, a significant better result (p < 0.05). For patients in whom we were able to excise the intimal tear (30.0%, early mortality rate), the results were better than in those in whom the intimal tear were left alone (53.8%). The results were particularly good in type T patients (25.0% of them underwent intimal tear resection and 71.4% underwent no operation for the intimal tear).(ABSTRACT TRUNCATED AT 250 WORDS)

Acute Disease↗
PubMed1988

Electronmicroscopic observation of the human facial nerve.

The facial nerves of Bell's palsy, Ramsay-Hunt's syndrome and traumatic facial palsy patients were studied using a transmission electron microscope. Changes were a proliferation of the collagen fibres, the degeneration of the Schwann cell, and a loosened or deteriorated myelin sheath. These changes differ considerably between individuals. Changes also vary in one subject. The cause and severity of the lesion, the duration of the palsy and the location of biopsy are possibly responsible for this phenomenon.

Adult↗
PubMed1987

Acoustic neuroma presenting with sudden and fluctuating hearing loss--a case report.

A case of acoustic neuroma presenting with sudden and fluctuating hearing loss is reported. The patient was a 38-year-old Japanese woman who noticed a sudden onset of hearing loss and tinnitus in the right ear. With a provisional diagnosis of sudden deafness, she was subjected to conservative therapy, including steroid hormone. The hearing started to recover and reached a normal level 2 months after the treatment. Meanwhile, the results of an ABR and plain skull X-rays aroused a suspicion of acoustic neuroma. She was operated on via a middle cranial fossa approach and an acoustic neuroma occupying the internal auditory meatus was removed.

Acute Disease↗
PubMed1981

Long-term clinical effect of calcium inhibitors in hypertrophic cardiomyopathy compared to the effect of beta-blocking agents. A preliminary report with special reference to the beneficial effect of nifedipine on angina pectoris.

Long-term clinical effects of beta-blockers (propranolol in most cases) and calcium inhibitors (nifedipine in most cases) were studied in 16 patients with hypertrophic cardiomyopathy. On overall subjective symptoms, beta-blockers were effective in 50% of symptomatic patients, while calcium inhibitors were effective in only 33%. On angina pectoris, however, calcium inhibitors were superior to beta-blockers in our patients. Blood pressure decreased with each drug, and the decrease was significant with nifedipine. Otherwise there was no change in physical findings with either drug. Long-term (more than 6 months) use of beta-blockers resulted in an increase in cardiothoracic ratio on chest X-ray, a decrease in left ventricular ejection fraction on echocardiogram and more pronounced ST-T change on electrocardiogram. Prolonged use of nifedipine resulted in a slight decrease in cardiothoracic ratio, but no systematic change on echocardiogram and on electrocardiogram.

Adrenergic beta-Antagonists↗