[Present-day views on the value of seroprophylaxis and serotherapy in gas gangrene].
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Biomedical subjects
Publications and source records attributed to T Orlowski.
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The authors describe the clinical use of Polish surgical glue "Chirurcoll-Polfa" (n-butylic, n-heptylic ester of cyano-acrylic acid) in aerosol and liquid form. The glue was applied in 1441 in- and outpatients with good results. The glue was applied on skin wounds, penetrating injuries of the eyeball and parenchymal organs (lungs, liver, pancreas, kidneys), on wounds after electrocoagulation of erosions of the cervix uteri. The glue was also useful in closure of cerebrospinal liquid leaks and gastrointestinal and bile fistulas. It was applied to tighten sutures and anastomoses of the gut and used during operations of the middle-ear.
The authors present an own method of hemodilution and experiences gained from 10 patients operated for chronic gastric or duodenal ulcer. The therapuetic results of the method show that it can be applied easely and safely in everyday surgical practice. In the patients treated with it no surgical and anaesthesiological complications could be observed during the operations as well as after them. The autors believe that the method of hemodilution for planned surgical operations will contribute to a more economical use of blood transfusions and to reduction in the occurrence of virus hepatitis.
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Studies to determine selected blood electrolyte concentrations showed no disturbances in serum sodium, chloride, and copper concentrations during and after moderate hemodilution to 30 per cent of hematocrit. Sudden significant decreases in serum potassium, magnesium, and total calcium concentrations at ten minutes after hemodilution were the result of physical dilution only and did not have negative effects on organs, especially the heart. We observed a significant decrease in serum iron concentration with a gradual return to the control value; we cannot explain this phenomenon because it resulted neither from dilution nor blood loss. Our results require that caution be exercised and that the dilution fluid employed be changed when more significant hemodilution (below 30 per cent of hematocrit) is intended, so that suspected, more intensive sudden alterations in electrolyte concentration are prevented.
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