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Biomedical subjects

T Olson

Publications and source records attributed to T Olson.

34 records · Page 2Linked to original sources
PubMed1990

A sojourn with two nurses of the Virgin Islands.

The experiences shared by Ms. Mitchell and Ms. Milligan represent a combined total of more than 80 years of work in nursing. As an introduction to nursing history in a small but vital part of the world, their observations suggest exciting ideas for further research. Such research might include an in-depth exploration of the history of the islands' system of nursing education, a study of the influence of the various island cultures on nursing education and practice, or a comparison between nursing practice in the islands and the mainland. It is hoped that this article might encourage others to explore further the rich history of nursing in the U.S. Virgin Islands.

History of Nursing↗
PubMed1990

Quantitative and functional assays compared for determination of zymogen and activated human protein C.

We evaluated quantitative and functional assays for protein C, using either purified protein C samples or pooled normal plasma as assay standards. The purified protein C samples were examined as the zymogen form and after activation by thrombin. Mass concentrations of protein C were determined by amino acid analysis and confirmed by enzyme-linked immunosorbent assay (ELISA). Functional activity was assessed in both standard clot inhibition and amidolytic assays. The accuracy and precision of the ELISA was acceptable, with all three preparations of protein C having similar linear curves. The clot inhibition assay demonstrated marked variability when used according to the manufacturer's instructions; however, modifications to the protocol significantly decreased the CV, to less than 10%. Both activated protein C and the zymogen gave linear standard curves. Pooled normal human plasma gave a nonlinear curve, which contributed to inaccurate sample recoveries. We obtained the most nearly accurate recoveries when we used activated protein C as the assay standard. Amidolytic assays provided no insights into the appropriateness of the preparations for that assay format. A uniform, consistent source of protein C, e.g., recombinant activated protein C, would be useful for standardizing all assays of protein C.

Enzyme Precursors↗
PubMed1986

Cryptosporidial infections in captive wild animals.

Neonatal diarrhea was an important cause of morbidity and mortality in a hand-rearing facility for exotic ruminants at the San Diego Wild Animal Park. Studies undertaken to determine the causes of the problem revealed that oocysts of Cryptosporidium sp. were demonstrable in auramine O stained fecal smears from 52 of 183 (28.4%) animals examined. Cryptosporidial infection was identified in 21 of 40 species of exotic ruminants with diarrhea. In addition, cryptosporidia were associated with gastroenteric disease in two primates and two reptiles. It was observed also that auramine O stained coccidial oocysts of the genus Eimeria, which were present in five of 183 (2.7%) of the specimens examined.

Animals↗
PubMedDate not supplied

Optimal time-frequency projections for localized tomography.

An algorithm for recovering a function from essentially localized values of its Radon transform and sparse nonlocal values was outlined in Reference 13. That algorithm utilized the time-frequency properties of wavelets, coupled with the range theorems for the Radon transform, to localize essentially the dependence of the Radon transform. In this paper we utilize alternative time-frequency projections which were introduced by Coifman and Meyer (4). We present evidence that these bases are optimal according to our criterion for localized tomography. These bases require significantly less data than the wavelet bases that were used in Reference 13. Finally, we present numerical results supporting this work.

Algorithms↗
PubMedDate not supplied

Transcultural care.

Explore the source record for details and available documents.

Ethics, Nursing↗
PubMedDate not supplied

Severely and persistently mentally ill in Hawaii: profile and implications.

This study examines the characteristics, treatment, and care of severely and persistently mentally ill clients at Hawaii's largest public-sector psychiatric facility, Hawaii State Hospital. The implications of this information are discussed in terms of treatment and care. As was found in previous studies, the 88 participants included in this study were mostly male, less than 40 years of age, with a high school education or less, and hospitalized under a penal code. More remarkable variations were revealed, however, when clients were grouped according to ethnicity and racial origin. For example, clients from marginalized groups had a significantly higher likelihood of violence than clients from more politically, economically, and socially powerful groups in Hawaii. The findings of this research challenge nurses to combine social advocacy with clinical expertise to provide effective and complete treatment and care.

Adult↗