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Biomedical subjects

T Okasora

Publications and source records attributed to T Okasora.

21 records · Page 2Linked to original sources
PubMed1983

Serum and erythrocyte acetylcholine esterase in Hirschsprung's disease.

Determination of acetylcholine esterase in serum (S-AChE) and erythrocytes (E-AChE) was carried out in nine patients with Hirschsprung's disease and 16 normal controls. S-AChE was significantly elevated in patients with Hirschsprung's disease, while no significant difference was observed in E-AChE in these two groups. In 17 patients with Hirschsprung's disease, S-AChE and E-AChE were determined after definitive operation. Twelve of these patients underwent a Duhamel type procedure in which a small part of the aganglionic bowel segment remained unresected. Five patients were treated by Swenson's procedure performing complete resection of the aganglionic bowel segment. S-AChE in patients treated by the Duhamel type procedure remained elevated, while it was as low as that in normal controls in patients who underwent Swenson's procedure. There was no significance in E-AChE in both groups. This study suggests a close relation of the level of S-AChE to the extent of the aganglionic bowel segment in Hirschsprung's disease.

Acetylcholinesterase↗
PubMed1983

[Second-look operation for childhood solid malignancy].

Forty-four cases with childhood solid malignancy during the period from 1973 to 1982, were analysed. 11 cases underwent second-look operation, including 4 neuroblastomas, 4 hepatoblastomas, 1 malignant teratoma, 1 nephroblastoma, and 1 rhabdomyosarcoma. Two cases of hepatoblastoma in second-look operation are surviving over two years with no evidence of disease, and one case survived 5 years 8 months. For one patient of initially unresectable neuroblastoma, second-look operation was successfully performed by complete resection followed by paraortic-lymphonode dissection. In two cases of Wilms' tumor and malignant teratoma, second-look operations were performed for the purpose of treatment decision after radical operation. In the unresectable tumors or recurrent tumors or metastatic lesions, complete cure can be expected by aggressive surgical approach and combination chemotherapy followed by second-or third-look operation.

Antineoplastic Combined Chemotherapy Protocols↗