[Functional adenomatous goiter].
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Biomedical subjects
Publications and source records attributed to T Ohara.
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Immunological tolerance is induced in mice by intrathymic injection of HSA. The tolerance thus induced is mediated by suppressor T cells. Strong tolerance persists more than 56 days after the induction, and the high efficiency of the tolerance thus induced is accounted for in terms of the number or the potentiality of suppressor cells. Possible mechanisms of suppressor T cell induction by iT injection of the antigen are discussed briefly.
We have observed rotational excursion, comprising anteroposterior and right to left movement of the heart, and cardiac twist around the long axis in 2 patients with massive pericardial effusion, using a phased-array echocardiograph recently developed in this country. Sagittal real-time cross-sections showed only the anteroposterior swing motion, but horizontal cross-sections revealed a counterclockwise rotational excursion and cardiac twist during this rotational excursion. The rotational excursion consisted of a rapid and almost straight movement right and posteriorly in systole, and a slow arcing excursion left and anteriorly in diastole. The speed of this movement was not uniform. The heart disclosed dominant counterclockwise twisting motions in mid to late systole and in late diastole, synchronous with atrial contraction. These movements were described relative to an external system of co-ordinates. Controls, consisting of a normal healthy subject, and cases with mitral stenosis, mitral regurgitation, and hypertrophic cardiomyopathy, did not show any rotational excursion. In the latter 2 diseases, cardiac twists were observed, but they were less dominant than in cases with massive pericardial effusion.
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Two patients with dissecting aneurysms of the aorta of Debakey type I and II, 10 healthy subjects, and 2 patients with signs mimicking aortic-root dissection were studied by two-dimensional echoaortocardiography, standard echocardiography, and M-mode scanning. In both electrocardiographically gated and nonelectrocardiographically gated two-dimensional echoaortocardiograms of each patient, aortic-root dissections were clearly visualized. Because of the possibility of a false-positive diagnosis of an aortic-root dissection by previously reported criteria (including cases in the authors' experience and in the literature), the authors are convinced that the combination of two-dimensional and standard echoaortocardiography provides the most reliable echo diagnosis of this disease.
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