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T Odberg

Publications and source records attributed to T Odberg.

10 recordsLinked to original sources

[Primary laser trabeculoplasty in glaucoma. A resource saving treatment].

During the last ten years argon laser trabeculoplasty has been shown to be a very useful tool in the treatment of glaucoma when medical therapy has failed. In the present study laser was used as primary therapy in 27 patients with newly detected glaucoma. Pretreatment with topical timolol gave an immediate pressure drop in all eyes, and the dreaded acute pressure rise after laser treatment was avoided. Upon follow-up examination after two years, more than half the patients had an intraocular pressure below 21 mm Hg without additional therapy. Primary laser trabeculoplasty was found to be a safe and time-saving procedure. Expenses and complications associated with medical therapy are reduced. Many patients may avoid lifelong daily instillation of eye drops.

Aged

Primary argon laser trabeculoplasty after pretreatment with timolol. A safe and economic therapy of early glaucoma.

In the treatment of glaucoma there are advantages and disadvantages associated with both medical, surgical and laser therapy. Early pressure rise has been found to be the main complication after laser treatment. In the present study primary argon laser trabeculoplasty (PALT) was carried out in 180 degrees of the trabecular meshwork with an effect of 0.4-0.6 W, after instillation of one drop of timolol 0.5%. Among our 27 newly diagnosed glaucoma patients no pressure rise or iritic reaction was detected. More than 50% of the patients were still managed with an intraocular pressure below 21 mmHg without medical or surgical treatment after 2 years. In addition to being virtually without side-effects this treatment modality is time saving and cost effective, and a great part of the patients may avoid medical therapy.

Aged

Early diagnosis of glaucoma. II. The value of the initial examination in ocular hypertension.

In a group of 46 patients with moderately elevated intraocular pressure (22-30 mmHg), signs of early glaucoma were found in half of them after a follow-up of 5-7.5 years. Most of the patients showed only a small increase in optic disc cupping revealed by stereophotography. Initial IOP higher than 25 mmHg, large pressure differences between the two eyes, large diurnal pressure variation, occurrence of pseudoexfoliation, pressure drop of more than 8 mmHg after topical epinephrine, and a pressure rise of more than 4 mmHg after water loading were more frequent in the group of patients who developed signs of glaucoma. Age, a positive family history, occurrence of cardiovascular disease, and the cup/disc ratio did not differ in the two groups of patients. The pilocarpine test and steroid provocation had no predictive value. Surprisingly, there was a small drop of pressure after topical steroids in 6 of the 8 patients with pseudoexfoliation.

Adult

Early diagnosis of glaucoma. The value of successive stereophotography of the optic disc.

A group of 46 patients with ocular hypertension (initial pressure 22-30 mmHg) have been followed prospectively for 5-7.5 years, with special emphasis on optic disc changes. A stereophoto of the disc was taken at each consultation. So far, 24 patients have been put on anti-glaucoma therapy. A slight increase in disc cupping revealed by stereophoto was the first pathological finding in 19 patients. Only one patient developed a field defect without visible disc changes. Neither disc description, cup/disc ratio measurement nor disc drawing were accurate enough to disclose small changes in the cup size. Considerably more patients in the treatment group had a pressure rise of 5 mm or more and repeated intraocular pressures of 30 mm or more during the observation. Stereophotography of the optic disc was found to be a valuable method in the diagnosis of early glaucoma.

Adult

Experimental tonography on enucleated human eyes. I. The validity of Grant's tonography formula.

When newer tables for parameters in Grant's formula for tonography are used, one obtains far higher values for the outflow facility than those generally accepted. The aim of this iinvestigation has, therefore, been to test the validity of the tonography formula. The outflow facility determined by constant-rate perfusion in enucleated eyes has been compared with the results of tonography on the same eyes in the steady-state condition. Loss of intraocular fluid during tonography has been measured directly by means of a new technique. Outflow facilities determined according to the two methods show very good agreement. Thus, when the production of aqueous is held at a constant rate, and when there is no change in intraocular blood volume. Grant's tonography formula is found valid, provided absolute values for Po, Pt, and dV are used.

Aged

Experimental tonography on enucleated human eyes. II. The loss of intraocular fluid caused by tonography.

In clinical work, the loss of intraocular fluid caused by tonography (dV) is usually calculated according to the formula of Grant and Friedenwald. The validity of this formula has been tested by comparing the dV calculated from known factors in the formula with the dV measured directly on enucleated eyes. Our results show a good correlation between the two methods, especially when the rigidity coefficient at the beginning of tonography is used in the calculations. It is concluded from our experiments here and in our previous paper that the theoretical foundation of tonography in principle is valid.

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