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Biomedical subjects

T Nolan

Publications and source records attributed to T Nolan.

96 records · Page 6Linked to original sources
PubMed1983

Recurrence of a gonadal stromal cell tumor (Sertoli Leydig cell with heterologous elements) in a teenager.

An unusual case of a moderately well-differentiated, encapsulated, Sertoli Leydig cell tumor with heterologous elements recurring 3 years after a conservative unilateral oophorectomy in a 15-year-old female is reported. This is the first case report of a metastatic Sertoli Leydig cell tumor with mucinous heterologous elements. A relative lack of uniformly accepted histological criteria of these tumors makes prognosis difficult to access. The optimal therapy for recurrent Sertoli Leydig cell tumor is unknown. Initial plans of management of this rare neoplasm, follow-up, and current concepts of treatment of recurrences will be discussed.

Adolescent↗
PubMedDate not supplied

Body dimensions, exercise capacity and physical activity level of adolescent Nandi boys in western Kenya.

The aim of this study was to characterize untrained Nandi boys (mean age 16.6 years) from a town (n = 11) and from a rural area (n = 19) in western Kenya (altitude approximately 2000 m.a.s.l.) in regard to their body dimensions, oxygen uptake and physical activity level. The town boys had a mean maximal oxygen uptake (VO(2 max)) of 50 (range: 45-60) mL kg(-1) min(-1), whereas the village boys reached a value of 55 (37-63) mL kg(-1) min(-1) ( p<0.01) in VO(2 max). The running economy, determined as the oxygen cost at a given running speed, was 221 mL kg(-1) km(-1) (597 mL kg(-0.75) km(-1)) for town as well as for village boys. The body mass index (BMI) was very low for town as well as for village boys (18.6 vs 18.4 kg m(-2)). The daily mean time spent working in the field during secondary school and doing sports were significantly higher in village boys compared to town boys (working in the field: 44.2 (0-128) vs 1.3 (0-11) min, p<0.01; sports: 32.0 (11-72) vs 12.8 (0-35) min, p<0.01, respectively). A positive correlation between the daily time spent doing sports and VO(2 max) was found when pooling the data from the town and the village boys (R = 0.55, p<0.01). It is concluded that the body dimensions of adolescent Nandi town and village boys corresponds well with findings in Kenyan elite runners. They are very slender with relatively long legs. In addition, the VO(2 max) of the village boys was higher than that of the town boys, which is probably due to a higher physical activity level of the village boys during secondary school.

Adolescent↗
PubMedDate not supplied

Community-based study of mortality in children with epilepsy.

We used the records of a statewide pediatric mortality surveillance system to determine mortality rates and causes of death in children with epilepsy. Of the 1,095 children aged 1-14 years who died in the state of Victoria during the study period 1985-1989, 93 had a history of epilepsy. Six children (6%) had primary epilepsy, and 87 (94%) had secondary epilepsy. Death was (a) directly attributable to epilepsy in 20 (22%), including 11 with sudden unexplained death, (b) not directly attributable to epilepsy in 59 (63%), and (c) of undetermined cause in 14 (15%). No classifiable death occurred as a direct result of status epilepticus. The average annual mortality rates for children with epilepsy were (a) death from all causes, 30.6 in 10,000 [95% confidence interval (CI) 19.7, 47.5], and (b) death attributable to epilepsy, 6.6 in 10,000 (95% CI 3.7, 11.8). Relative to the all-cause mortality rate in children without epilepsy, the all-cause mortality rate ratios were (a) all children with epilepsy, 13.2 (95% CI 8.5, 20.7); (b) primary epilepsy, 1.1 (95% CI 0.5, 2.6); and (c) secondary epilepsy, 49.7 (95% CI 31.7, 77.9). The mortality rate ratios for secondary epilepsy relative to primary epilepsy were (a) death from all causes, 43.5 (95% CI 19.0, 99.5); and (b) death attributable to epilepsy, 9.0 (95% CI 3.3, 24.8). Epilepsy appeared on the death certificate of only 11 of 20 (55%) children whose deaths were attributable to epilepsy.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗