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Biomedical subjects

T Niemiec

Publications and source records attributed to T Niemiec.

3 recordsLinked to original sources

Psychosocial intervention in the process of empowering families with children living with HIV/AIDS-a descriptive study.

The notion of 'family empowerment' is of crucial importance in any kind of psychosocial intervention directed to families with children living with HIV/AIDS. The goal is to restore self-efficacy and self-esteem, encourage positive coping and help family members make their own choices. Two settings for psychosocial intervention are described: an outpatient clinic within a larger medical institution and a therapeutic camp for families with children. Different psychotherapeutic and counselling strategies and approaches are briefly presented. Preliminary results based on work with families with children infected and/or affected by HIV/AIDS are described. The conclusion is that interventions that involve different settings seem to be most effective, especially for the most vulnerable families. The important issue is also collaboration between different service providers and NGOs.

Adaptation, Psychological↗

Microwave radiation enhances teratogenic effect of cytosine arabinoside in mice.

Impregnated Swiss mice were irradiated 2 h daily on days 1-18 of gestation in nonthermal (1 or 10 mW/cm2) or thermogenic (40 mW/cm2) 2,450-MHz microwave (MW) fields. On the 19th day of pregnancy all dams were killed to check the number of resorptions. Living fetuses were isolated, weighed and checked for the presence of macroscopically visible malformations of skeleton and cleft palate (CP) and/or lip (CLP). Some of the pregnant mice in each group were injected intraperitoneally on the 9th day of gestation with 10 mg/kg of cytosine arabinoside (ara-C), a well-known teratogen resulting under the above conditions in the appearance of about 15% (42 of 354) of resorbed implantation points and the development of CP or CLP in about 30% (96 of 312) of fetuses. Exposure to nonthermal MW fields during pregnancy did not lead to resorptions or detectable malformations; however, the body mass of 19-day fetuses was significantly lower than in sham-irradiated controls. MW hyperthermia (40 mW/cm2) applied during pregnancy led to an increased number of resorptions - about 25% (37 of 157) compared to 2% (6 of 306) in controls. Significant enhancement of the teratogenic potency of ara-C was observed after combined exposure to both ara-C and MWs during pregnancy. In dams treated with ara-C alone about 20% (62 of 358) resorptions and about 30% (91 of 296) fetuses with CL or CLP were found; additional exposure in MW fields (10 mW/cm2), not resulting per se in resorptions or detectable malformations, increased the numbers to 45% (213 of 448) of resorptions and to 70% (167 of 235) fetuses with CL or CLP.+

Abnormalities, Drug-Induced↗